fusarium, a genus of Pezizomycotina, consists of approximately 300 species. Some species like f. graminearum, f. oxysporum, f. proliferatum, f. solani and f. verticillioides are phytopathogenic and cause fusarium head...
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fusarium, a genus of Pezizomycotina, consists of approximately 300 species. Some species like f. graminearum, f. oxysporum, f. proliferatum, f. solani and f. verticillioides are phytopathogenic and cause fusarium head blight or fusarium wilt. fusarium species produce mycotoxins, which are of particular relevance in wheat, barley and maize. One of the latest and effective control strategies to combat these pathogens is based on silencing of essential genes by host-induced gene silencing (HIGS). Recently, several researchers have successfully silenced important genes encoding cytochrome P450, chitin synthase, protein kinases and others in f. graminearum, f. oxysporum, f. culmorum and f. verticillioides, leading to reduced mycotoxin production. In this review we will cover reports indicating HIGS as a powerful tool for the control offusarium spp. infections in plants.
The capability of individuals to manage their finances is essential to the outcomes of their entrepreneurial activities. Using panel data from the China Household finance Survey (C.H.f.S.) in 2013, 2015 and 2017, this...
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The capability of individuals to manage their finances is essential to the outcomes of their entrepreneurial activities. Using panel data from the China Household finance Survey (C.H.f.S.) in 2013, 2015 and 2017, this article examines how financial capability affects entrepreneurial performance in rural China. The results demonstrate that financial capability is positively correlated with the scale, profitability and sustainability of entrepreneurship, which is robust in consideration of endogeneity. The effects offinancial capability are heterogeneous for different entrepreneurs. furthermore, technology, labour and land act as the mediating variables through which financial capability improves entrepreneurial performance. Therefore, to facilitate entrepreneurial success, it is important to provide entrepreneurs with financial education. Meanwhile, improvements to the financial environment should also be considered. Additionally, financial institutions should combine financial services with factors, such as technology, land and labour, to improve entrepreneurial performance.
Prior studies suggest autism-specific and general developmental screens are complementary for identifying both autism and developmental delay (DD). Parents completed autism and developmental screens before 18-month vi...
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Prior studies suggest autism-specific and general developmental screens are complementary for identifying both autism and developmental delay (DD). Parents completed autism and developmental screens before 18-month visits. Children with failed screens for autism (n = 167) and age, gender, and practice-matched children passing screens (n = 241) completed diagnostic evaluations for autism and developmental delay. When referral for autism and/or DD was considered, overall false positives from the autism screens were less frequent than for referral for autism alone. Presence of a failed communication subscale in the developmental screen was a red flag for autism and/or DD. An ordinally-scored autism screen had more favorable characteristics when considering autism and/or DD, yet none of the screens achieved recommended standards at 18 months, reinforcing the need for recurrent screening as autism emerges in early development.
In this study, we investigated the dynamics of microbial community and flavor metabolites during the traditional fermentation of Hongqu aromatic vinegar (HAV) and subsequently explored the potential relationship betwe...
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In this study, we investigated the dynamics of microbial community and flavor metabolites during the traditional fermentation of Hongqu aromatic vinegar (HAV) and subsequently explored the potential relationship between microbiota and flavor metabolites. The microbiome analysis based on high-throughput sequencing (HTS) of amplicons demonstrated that Lactobacillus, Acetobacter and Clostridium were the dominant bacterial genera, while Alternaria, Candida, Aspergillus and Issatchenkia were the dominant fungal genera during the acetic acid fermentation (AAf) of HAV. A total of 101 volatile flavor compounds were identified through gas chromatography-mass spectrometry (GC-MS) during HAV fermentation, including esters (35), alcohols (17), aldehydes (11), acids (11), ketones (7), phenols (10), and others (10). Redundancy analysis (RDA) was used to reveal the correlation between microbiota and volatile flavor compounds. Lactobacillus and Acetobacter were the two bacterial genera that have the great influence on the production of volatile flavor components in HAV. Among them, Lactobacillus was positively correlated with a variety of ethyl esters, while Acetobacter positively contributed to the formation of several organic acids. furthermore, the non-volatile metabolites were detected by ultra-high-performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-QTOf/ MS). A total of 41 dipeptides were identified during HAV fermentation, and most of them may have sensory characteristics and biological activities. RDA showed that Aspergillus, Epicoccum, Issatchenkia, Candida and Malassezia were the most influential fungal genera on non-volatile metabolites. In particular, Epicoccum was first reported in Hongqu vinegar and showed a positive correlation with the production of various organic acids. In conclusion, this study provides a scientific basis for understanding the flavor generation mechanism of HAV, and may be valuable for developing effective tec
In model-based inference of population structure from individual-level genetic data, individuals are assigned membership coefficients in a series of statistical clusters generated by clustering algorithms. Distinct pa...
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In model-based inference of population structure from individual-level genetic data, individuals are assigned membership coefficients in a series of statistical clusters generated by clustering algorithms. Distinct patterns of variability in membership coefficients can be produced for different groups of individuals, for example, representing different predefined populations, sampling sites or time periods. Such variability can be difficult to capture in a single numerical value;membership coefficient vectors are multivariate and potentially incommensurable across predefined groups, as the number of clusters over which individuals are distributed can vary among groups of interest. further, two groups might share few clusters in common, so that membership coefficient vectors are concentrated on different clusters. We introduce a method for measuring the variability of membership coefficients of individuals in a predefined group, making use of an analogy between variability across individuals in membership coefficient vectors and variation across populations in allele frequency vectors. We show that in a model in which membership coefficient vectors in a population follow a Dirichlet distribution, the measure increases linearly with a parameter describing the variance of a specified component of the membership vector and does not depend on its mean. We apply the approach, which makes use of a normalized f-ST statistic, to data on inferred population structure in three example scenarios. We also introduce a bootstrap test for equivalence of two or more predefined groups in their level of membership coefficient variability. Our methods are implemented in the r package fSTruct.
This essay re-examines the origins of Herman Bavinck's organic motif. Contending with a central claim of the new interpretative paradigm in Bavinck studies, this article problematises the claim that Bavinck's ...
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This essay re-examines the origins of Herman Bavinck's organic motif. Contending with a central claim of the new interpretative paradigm in Bavinck studies, this article problematises the claim that Bavinck's organic motif does not draw on German idealism but derives solely from a classical western doctrine of the Trinity. This essay argues that the denial of Schelling's influence on Bavinck's organicism misconstrues the terms on which Bavinck forges his synthesis of orthodoxy and modernity, and cloaks the degree to which Bavinck allows philosophical constructs to determine the material content of his theology.
Technological advances associated with computing power and the prospect of artificial in-telligence have renewed interest on the economic feasibility of socialism. The question of such feasibility turns on whether the...
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Technological advances associated with computing power and the prospect of artificial in-telligence have renewed interest on the economic feasibility of socialism. The question of such feasibility turns on whether the problem of economic calculation has fundamentally changed. In spite of the prospect of what King and Petty (2021) refer to as "technosocial-ism," we argue that technological advances in computation cannot replace the competitive discovery process that takes place within the context of the market. We do so by situating the case for technosocialism in the context of the socialist calculation debate. Understood in these terms, technosocialism represents a restatement of the case for market socialism, which incorrectly framed the "solution" to economic calculation under socialism as one of computing data, rather than the discovery of context-specific knowledge that only emerges through the exchange of property rights. Therefore, the arguments put forth by Ludwig von Mises and f.A. Hayek, and later Israel Kirzner and Don Lavoie, regarding the impossibility of economic calculation under socialism remains just as relevant today. (c) 2022 Elsevier B.V. All rights reserved.
The issue of climate change and environmental degradation has been prevailing for the last few decades. Yet economies are further expanding due to free trade agreement which accelerates the trade of energy and carbon ...
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The issue of climate change and environmental degradation has been prevailing for the last few decades. Yet economies are further expanding due to free trade agreement which accelerates the trade of energy and carbon intensive commodities across the regions. A prominent example of such free trade is the Regional Comprehensive Economic Partnership (R.C.E.P.), which mostly remains ignored. The current research study explores the influence offinancial development (f.D.) and energy efficiency (E.N.E.f.) on carbon emissions in the R.C.E.P. economies. Also, this study analyses the role of economic growth and renewable energy on environmental quality during the period from 1990 to 2020. Panel data approaches such as slope heterogeneity, cross-section dependence, and the second-generation panel unit root test are used. The non-normally distributed variables are found cointegrated. Therefore, a novel method of moments quantile regression is used. The results demonstrate that f.D. and economic growth are positively associated with CO2 emissions. At the same time, E.N.E.f. and renewable energy consumption (R.E.C.) significantly reduce the emissions level and promote a green environment in all quantiles. The environmental Kuznets curve is found valid in the R.C.E.P. economies. These results are robust as validated by fully-Modified Ordinary Least Square - a parametric approach. A two-way significant causal association exists between carbon-economic growth, carbon-f.D., carbon-R.E.C., and carbon-E.N.E.f.. The findings suggest an enhancement in R.E.C., improvement in the E.N.E.f. approaches, and implications for green f.D. in the region.
Sexual reproduction is almost universal in vertebrates;therefore, each animal species which uses it must have a mechanism for designating sex as male or female. fish, especially, have a wide range of sex determining s...
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Sexual reproduction is almost universal in vertebrates;therefore, each animal species which uses it must have a mechanism for designating sex as male or female. fish, especially, have a wide range of sex determining systems. In the present study, we aimed to identify a genetic basis for sex determination in the common creek chub (Semotilus atromaculatus) using genotyping-by-sequencing data. No sex-associated markers were found by RADSex or a GWAS using GEMMA;however, Weir and Cockerham locus-specific f-ST analysis and discriminant analysis of principal components revealed genetic differentiation between the sexes at several loci. While no explicit sex determination mechanism has been yet discovered in creek chub, these loci are potential candidates for future studies. Incompatible systems are thought to increase reproductive isolation but interspecific hybridization is common among groups such as cyprinid minnows;thus, studies such as ours can provide insight into hybridization and evolutionary diversification of this clade. We also highlight technical challenges involved in studying sex determination in evolutionary groups with extremely variable mechanisms and without heteromorphic sex chromosomes.
Previously, rainbow trout fed deoxynivalenol (DON) or partially fed (pair-fed) for 4 weeks before and during experimental infection with flavobacterium psychrophilum had significantly decreased mortality rates. Simila...
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Previously, rainbow trout fed deoxynivalenol (DON) or partially fed (pair-fed) for 4 weeks before and during experimental infection with flavobacterium psychrophilum had significantly decreased mortality rates. Similar results were obtained in the present study after 12 days, but not after 6 days, feeding 5 ppm DON or pair-fed before infection. furthermore, feeding 250 ppm chloroquine (CQ) also reduced mortality (p = .052) compared with controls and may have promise for treatment of some fish disease. Parallel groups offish were maintained on the respective treatments for 15 days, with an additional group that was fasted, but were not infected to monitor autophagy. fish that were fasted or fed DON had significantly increased LC3II in the liver and fasted fish had significantly decreased LC3II in muscle compared with controls using western blot. There was no difference in LC3II signal in the spleen of any treatment group. fish that were fasted or pair-fed had significant up-regulation of the Atg genes atg4, atg7, lc3, gabarap and atg12 in muscle using quantitative PCR. Less alteration of Atg expression was seen in liver. fish treated with CQ had significantly increased expression of atg4, becn1, lc3 and atg12 in the liver. fish fed DON for 15 days had few alterations of Atg genes in either the liver or muscle. It is still not clear if autophagy is responsible for the resistance of rainbow trout fed DON, CQ or pair-fed before f. psychrophilum infection.
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