We used gaussianmodeling to depict the changes in finger photoplethysmographic (PPG) pulse during pregnancy in healthy women. We enrolled 70 healthy pregnant women and recorded their PPG pulses in 11-13 gestational w...
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We used gaussianmodeling to depict the changes in finger photoplethysmographic (PPG) pulse during pregnancy in healthy women. We enrolled 70 healthy pregnant women and recorded their PPG pulses in 11-13 gestational weeks, 20-22 gestational weeks, and 37-39 gestational weeks. Three independent positive gaussian functions were utilized to decompose the pulses, and each gaussian function extracted three key parameters: the peak amplitude (H), the peak position (T), and the half-width (W). The method of ANOVA and post-hoc multiple comparisons of mathematical statistics were utilized to study the differences of these parameters between the three trimesters. We found that in the first trimester H-1 increased significantly (H-1 : 49.7 +/- 10.3 versus 52.9 +/- 6.9, p < 0.05). T-2 and T-3 increased in the first trimester (T-2 : 28.1 +/- 2.8 versus 28.4 +/- 2.2, p > 0.05;T-3: 54.3 +/- 4.2 versus 56.3 +/- 4.3, p < 0.01), then decreased significantly (T-2 : 28.4 +/- 2.2 versus 27.3 +/- 2.2, T-3: 56.3 +/- 4.3 versus 54.7 +/- 5.2, p < 0.05). H-1 is associated with cardiac output, and T-2 and T-3 are associated with peripheral vascular resistance. The results of this study were consistent with the conclusion that healthy pregnant women exhibited high flow state of the cardiovascular system and their peripheral vascular resistance decreased first and then gradually recovered during pregnancy. This study indicated that PPG pulse could also reflect the changes in the maternal cardiovascular system during pregnancy.
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