Control theoretic measures are proposed to assess motor performance in Parkinson's disease (PD), a neurodegenerative disorder that impairs motor skills, speech, and aspects of cognition. Ten normal and 14 PD subje...
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Control theoretic measures are proposed to assess motor performance in Parkinson's disease (PD), a neurodegenerative disorder that impairs motor skills, speech, and aspects of cognition. Ten normal and 14 PD subjects performed a series of manual pursuit tracking tasks: three tasks were first performed separately, then as a merged sequence with sudden, unenunciated task changes. The tasks differed in whether the tracking errors appeared amplified, attenuated or unaltered. From the discrete block experiments, subject- and task-specific second-order, linear time invariant models were derived, with the trajectory subjects are asked to track as input and the subject's motor response as output. Multiple model adaptive estimation was employed on the merged sequences to determine whether, and with what delay, each subject modified their performance after a task change. Although all normal subjects detected the task change, less than one-third of PD subjects did (and with longer delay). Further, those PD subjects who detected the task change had estimators with higher damping ratio than those PD subjects who did not. Since cerebellar structures may affect damping ratio, and the basal ganglia are often associated with switching behaviour, the proposed method provides a comprehensive assessment of motor structures that may be affected in PD.
Manual control cybernetics aims to understand and describe how humans control vehicles and devices, such that more effective human-machine interfaces can be designed. Current cybernetics theory is primarily based on t...
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This paper addresses the problem of state estimation in the presence of unknown inputs if the system is dependent on an uncertain parameter. Multiple model Adaptive Estimation is applied to state and unknown input obs...
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作者:
Zhang, QinghuaInria
IFSTTAR Université de Rennes Campus de Beaulieu Rennes Cedex35042 France
The local approach to linear parameter varying (LPV) system identification consists in interpolating a collection of lineartimeinvariant (LTI) models, which have been estimated from data acquired at different workin...
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The effects of uncertainties on the performance of a Certainty Equivalent Open Loop Feedback Control approach is investigated throughout simulations of the Quebec Urban Community Sewer Network. The optimization algori...
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The effects of uncertainties on the performance of a Certainty Equivalent Open Loop Feedback Control approach is investigated throughout simulations of the Quebec Urban Community Sewer Network. The optimization algorithm is based on nonlinear programming with the peculiarity that all the constraints are linear. The hydraulic routine is a lineartimeinvariant (LTI) model associated to a Kalman filter. Preliminary results show the benefit of adding a filtering action to guarantee robust performance in the presence of measurement errors and model mismatch. The selected control scheme seems to be a good compromise between the short computational time required for Real time Control applications and the high performance expected in the presence of uncertainties. (C) 1997 IAWQ. Published by Elsevier Science Ltd.
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