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Comparing the mapping between EQ-5D-5L, EQ-5D-3L and the EORTC-QLQ-C30 in non-small cell lung cancer patients

HEALTH AND QUALITY OF LIFE OUTCOMES 2016年第1期14卷 1-15页

作者： Khan, Iftekhar Morris, Steve Pashayan, Nora Matata, Bashir Bashir, Zahid Maguirre, Joe Univ Surrey Clin Trials Unit Guildford England Univ Surrey Dept Hlth Econ Guildford England UCL Dept Appl Hlth Res London England Liverpool Heart & Chest Hosp Liverpool Merseyside England Univ Birmingham Canc Sch Birmingham W Midlands England

Background: Several mapping algorithms have been published with the EORTC-QLQ-C30 for estimating EQ-5D-3L utilities. However, none are available with EQ-5D-5L. Moreover, a comparison between mapping algorithms in the same set of patients has not been performed for these two instruments simultaneously. In this prospective data set of 100 non-small cell lung cancer (NSCLC) patients, we investigate three mapping algorithms using the EQ-5D-3L and EQ-5D-5L and compare their performance. Methods: A prospective non-interventional cohort of 100 NSCLC patients were followed up for 12 months. EQ-5D-3L, EQ-5D-5L and EORTC-QLQ-C30 were assessed monthly. EQ-5D-5L was completed at least 1 week after EQ-5D-3L. A random effects linear regression model, a beta-binomial (BB) and a Limited Variable Dependent Mixture (LVDM) model were used to determine a mapping algorithm between EQ-5D-3L, EQ-5D-5L and QLQ-C30. Simulation and cross validation and other statistical measures were used to compare the performances of the algorithms. Results: mapping from the EQ-5D-5L was better: lower AIC, RMSE, MAE and higher R-2 were reported with the EQ-5D-5L than with EQ-5D-3L regardless of the functional form of the algorithm. The BB model proved to be more useful for both instruments: for the EQ-5D-5L, AIC was -485, R-2 of 75 %, MAE of 0.075 and RMSE was 0.092. This was -385, 69 %, 0.099 and 0.113 for EQ-5D-3L respectively. The mean observed vs. predicted utilities were 0.572 vs. 0.577 and 0.515 vs. 0.523 for EQ-5D-5L and EQ-5D-3L respectively, for OLS;for BB, these were 0.572 vs. 0.575 and 0.515 vs. 0.518 respectively and for LVDMM 0.532 vs 0.515 and 0.569 vs 0.572 respectively. Less over-prediction at poorer health states was observed with EQ-5D-5L. Conclusions: The BB mapping algorithm is confirmed to offer a better fit for both EQ-5D-3L and EQ-5D-5L. The results confirm previous and more recent results on the use of BB type modelling approaches for mapping. It is recommended that in studies where

关键词： Root Mean Square Error NSCLC Patient mapping algorithm Poor Health State Mean Absolute Error

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Review on remote sensing data-based stream mapping algorithms

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FOREST SCIENCE AND TECHNOLOGY 2013年第2期9卷 87-96页

作者： Park, Joowon Kyungpook Natl Univ Dept Forestry 80 Daehak Ro Daegu 702701 South Korea

With the recognition of climate change effects on water resources, the demand for better stream management has increased in an effort to enhance overall water resources management. While various efforts have been carried out for better stream management, the role of small upper streams in forests becomes more and more highlighted due to its significant importance in modeling hydrological processes as well as controlling non-point source pollution. One of the problems in managing small streams in forests is the lack of reliable small stream maps or small stream mapping methods, particularly applicable for dense forest areas. In order to improve small stream mapping methods, many researchers have given their attention to the development of an automatic stream-mapping method by utilizing remote sensing data. Thus, this paper reviews the characteristics and effectiveness of various automatic remotely sensed data-based stream mapping methods that have been introduced up to now, and tries to draw implications for future studies. From the review, existing remote sensing data-based stream mapping approaches are found to be in one of three major categories: spectral data-based, digital elevation model (DEM)-based, and multiple-data-based approach. The spectral data-based approach was the initial method of utilizing satellite images, and became less popular due to its inherent weakness in that light cannot transmit through dense canopy. Its alternative, the DEM data-based approach, has become more and more centered in recent studies on the development of stream mapping methods, but the approach also has a disadvantage in that the DEM does not carry any information on the water itself, which is the core part of stream identification. Most recently, utilizing multiple data is suggested as a prominent approach in stream mapping research. Therefore, researchers developing stream mapping algorithms are recommended to focus on utilizing spectral data in addition to DEM data.

关键词： remote sensing stream mapping algorithm water resources

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Dynamic Resource Allocation algorithm based on Service Component 5

Dynamic Resource Allocation Algorithm based on Service Compo...

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5th International Conference on Computer Science and Network Technology (ICCSNT)

作者： Niu Yuanyuan Hu Hongchao Cheng Guozhen Henan Agr Broadcasting & Televis Sch Zhengzhou Henan Peoples R China Natl Digital Switching Syst Engn Technol R&D Ctr Zhengzhou Henan Peoples R China

ISBN: (纸本)9781509021291

Current network architecture suffers overloading due to extensive resource utility. This paper proposes a resource mapping algorithm upon service layer of service-based network: the unit of service component requests resource as well as limits;an agent is embedded in the component to surveil the utility of network resource. If network resource violates the limits, agent will punish the component. Our validation shows that mapping algorithms upon nodes and links can layout resource efficiently;when the resource is used by a component which exceeds its authority, punishment will be executed rapidly for impartiality.

关键词： service-based network resource allocation mapping algorithm utility function

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Multiprocessor Task Programming and Flexible Load Balancing for Time-stepping Methods on Heterogeneous Cloud Infrastructures

Multiprocessor Task Programming and Flexible Load Balancing ...

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IEEE Conference on SmartWorld, Ubiquitous Intelligence and Computing, Advanced and Trusted Computing, Scalable Computing and Communications, Cloud and Big Data Computing, Internet of People and Smart City Innovation

作者： Rauber, Thomas Ruenger, Gudula Univ Bayreuth Bayreuth Germany Tech Univ Chemnitz Chemnitz Germany

ISBN: (纸本)9781728140346

This article considers the execution of CSE applications on cloud infrastructures with heterogeneous hardware elements. For an efficient and reliable execution of long-running, time-consuming CSE applications, we pursue a programming model of multiprocessor-tasks (M-Tasks) which can be flexibly mapped onto the resources of the heterogeneous cloud infrastructure, thus supporting scalability. To capture the heterogeneity, we introduce variants of M-tasks and types for M-task as well as for hardware resources. Especially, we propose a two-stage procedure consisting of an offline mapping algorithm for typed M-tasks variants onto the typed hardware resources and an online execution protocol. The online execution protocol accompanies the actual execution by a monitoring of the execution time and the execution success as well as a bookkeeping for the successful and efficient execution of M-tasks. The approach is especially suited for time-stepping methods, since an adaptation of the execution strategy can be performed between time steps in case of failure or inefficient execution.

关键词： multiprocessor-task heterogeneous hardware Cloud infrastructure mapping algorithm execution protocol

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Conversion of the Seattle Angina Questionnaire into EQ-5D utilities for ischemic heart disease: a systematic review and catalog of the literature

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CLINICOECONOMICS AND OUTCOMES RESEARCH 2014年第1期6卷 253-268页

作者： Wijeysundera, Harindra C. Farshchi-Zarabi, Sara Witteman, William Bennell, Maria C. Sunnybrook Hlth Sci Ctr Div Cardiol Schulich Heart Ctr Toronto ON Canada Univ Toronto Inst Hlth Policy Management & Evaluat Toronto ON Canada St Michaels Hosp Inst Clin Evaluat Sci Toronto ON Canada St Michaels Hosp Li Ka Shing Knowledge Inst Toronto ON Canada Ctr Hosp Univ Quebec Charlesbourg PQ Canada

Background: There is a paucity of preference-based (utility) measures of health-related quality of life for patients with ischemic heart disease (IHD);in contrast, the Seattle Angina Questionnaire (SAQ) is a widely used descriptive measure. Our objective was to perform a systematic review of the literature to identify IHD studies reporting SAQ scores in order to apply a mapping algorithm to convert these to preference-based scores for secondary use in economic evaluations. Methods: Relevant articles were identified in MEDLINE (Ovid), EMBASE (Ovid), Cochrane Library (Wiley), HealthStar (Ovid), and PubMed from inception to 2012. We previously-developed and validated a mapping algorithm that converts SAQ descriptive scores to-European-Quality of Life-5 Dimensions (EQ-5D) utility scores. In the current study, this mapping algorithm was used to estimate EQ-5D utility scores from SAQ scores. Results: Thirty-six studies met the inclusion criteria. The studies were categorized into three groups, ie, general IHD (n=13), acute coronary syndromes (n= 4), and revascularization (n=19). EQ-5D scores for patients with general IHD were in the range of 0.605-0.843 at baseline, and increased to 0.649-0.877 post follow-up. EQ-5D scores for studies of patients with recent acute coronary syndromes increased from 0.706-0.796 at baseline to 0.795-0.942 post follow-up. The revascularization studies had EQ-5D scores in the range of 0.616-0.790 at baseline, and increased to 0.653-0.928 after treatment;studies that focused only on coronary artery bypass grafting increased from 0.643-0.788 at baseline to 0.653-0.928 after grafting, and studies that focused only on percutaneous coronary intervention increased in score from 0.616-0.790 at baseline to 0.668-0.897 after treatment. Conclusion: In this review, we provide a catalog of estimated health utility scores across a wide range of disease severity and following various interventions in patients with IHD. Our catalog of EQ-5D scores can be use

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Generation of OWL Ontologies from Confinement Models 1st

Generation of OWL Ontologies from Confinement Models

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1st Conference on Creativity in Intelligent Technologies and Data Science (CIT and DS)

作者： Zhukova, Irina Kultsova, Marina Litovkin, Dmitry Kozlov, Dmitry Volgograd State Tech Univ Volgograd Russia

ISBN: (纸本)9783319237664;9783319237657

This paper presents an approach to integration between conceptual model, such as confinement model (CM), and ontology encoded in OWL language. A new method for generation of OWL-ontology from confinement models was developed on the basis of mapping the components of CM into basic components of OWL-ontology. The proposed method and mapping algorithm were implemented in form of software tool and applied for generation of ontology from CM in the domain of human resource management. It is planned to integrate it with CBR-based intelligent decision support system in human resource management.

关键词： confinement system confinement model OWL-ontology conceptual modeling mapping algorithm human resource management

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A Visual Tool for DNA Repeats Screening 37

A Visual Tool for DNA Repeats Screening

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37th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC)

作者： Pop, Petre G. Vaida, Mircea F. Tech Univ Cluj Napoca Cluj Napoca Romania

ISBN: (纸本)9781424492701

DNA sequence analysis has been developing to reveal some hidden structure, to distinguish coding from noncoding regions in DNA sequence, and to explore structural similarity among DNA sequences. DNA repeats are associated with human disease, seems to play a role in genome organization and evolution and are important in regulatory processes. A lot of the methods for finding repeated sequences use signal processing techniques which implies distances, similarities and consensus sequences to generate candidate sequences. This paper presents results obtained using a mapping algorithm and a custom dot-plot analysis combined with image processing techniques, to isolate the position of DNA patterns with different lengths.

关键词： DNA diseases genomics image processing molecular biophysics DNA patterns DNA repeats screening DNA sequence analysis consensus sequences custom dot-plot analysis genome organization hidden structure image processing techniques mapping algorithm noncoding regions signal processing techniques visual tool algorithm design and analysis Bioinformatics Feature extraction Genomics Hamming distance Signal processing algorithms

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Multi-Operator Cell Tower Locations Prediction from Crowdsourced Data 30

Multi-Operator Cell Tower Locations Prediction from Crowdsou...

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30th International Conference on Computer Communications and Networks (ICCCN)

作者： Rahman, Mostafizur Hossain, Mohammad Arif Yuksel, Murat Univ Texas Rio Grande Valley Dept Elect & Comp Engn Edinburg TX 78539 USA New Jersey Inst Technol Dept Elect & Comp Engn Newark NJ 07102 USA Univ Cent Florida Dept Elect & Comp Engn Orlando FL 32816 USA

ISBN: (纸本)9780738113302

Cell tower locations are not publicly available due to business interests of wireless providers. Very often wireless providers provide exaggerated coverage maps that may mislead the public. In addition to providing a neutral check on the coverage maps, prediction of cell tower locations hosting multiple operators' access nodes could also be helpful in disaster communications and public safety in general. The localization of the disaster-affected towers can be very conducive to respond and reach to the victims. Further, victims' devices could utilize this knowledge to initiate device-to-device (D2D) or unmanned aerial vehicular (UAV) communications as alternatives to the damaged cellular infrastructure. Publicly available crowdsourced cell (base station) locations and FCC's sites can be used to predict the cell tower/site locations in the United States. In this work, we utilized a weighted k-means algorithm to predict cell tower locations from OpenCellid crowdsourced dataset and implemented a mapping algorithm to locate nearest physical towers. We map the predicted towers to two different sources of physical towers. Our comparison shows a significant accuracy in predicting tower locations regardless of sources of physical towers. The technique can be used to predict the tower locations in other countries as well.

关键词： Cell Sites Disaster Management Clustering algorithm mapping algorithm

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VisualNoC: A Visualization and Evaluation Environment for Simulation and mapping 16

VisualNoC: A Visualization and Evaluation Environment for Si...

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3rd ACM International Workshop on Many-Core Embedded Systems (MES)

作者： Wang, Junshi Huang, Yang Ebrahimi, Masoumeh Huang, Letian Li, Qiang Jantsch, Axel Li, Guangjun Univ Elect Sci & Technol China Chengdu 611731 Sichuan Peoples R China TU Wien A-1040 Vienna Austria Royal Inst Technol Stockholm Sweden Univ Turku Turku Finland

ISBN: (纸本)9781450342629

Simulation is the most common approach to evaluate Network on Chip (NoC) designs and many simulators at different abstraction levels have been developed so far. However, researchers have to spend a considerable amount of time and effort to debug, analyze, and extract meaningful information from the simulator reports. In this work, we propose a full-system visualization framework, called VisualNoC, that support both network simulation and task mapping. VisualNoC operates in a cycle-accurate mode and is based on an event-based trace model which can record the behaviors of routers, processing elements and packets. The visualization interface can provide efficient debugging and analysis platform by representing the simulation process and results in a variety of ways. One of the main features of VisualNoC is providing an intuitive way of analyzing the efficiency of different mapping algorithms that helps in finding bottlenecks and optimizing the design.

关键词： Visualization Simulator Many-Core System Network-onChip mapping algorithm Debug Statistics

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A Dynamic mapping Method to Keep Region Connectedness in DVE Systems

A Dynamic Mapping Method to Keep Region Connectedness in DVE...

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IEEE Information Technology, Networking, Electronic and Automation Control Conference (ITNEC)

作者： Zhang, Wei Zhou, Hangjun Natl Univ Def Technol Coll Comp Changsha Hunan Peoples R China Hunan Coll Finance & Econ Dept Informat Management Changsha Hunan Peoples R China

ISBN: (纸本)9781467391948

Multi-server infrastructure is often used to enhance the scalability of Distributed Virtual Environment (DYE) systems. Under this infrastructure, assigning all clients to proper servers, also referred to as the mapping problem, is a key issue as it affects the overall system performance and the interactive experience of the participants. Most traditional mapping methods consider the load balancing problem or the communication delay between clients and servers, but ignore the influence of the virtual world integrity in the mapping process. In this study, we propose a novel dynamic mapping algorithm which can keep the connectedness of all regions in the virtual world and effectively maintain its integrity. Simulation results show that our algorithm greatly decreases the costs of DVE systems for migration of clients and improves the users' degree of satisfaction.

关键词： DVE systems mapping algorithm virtual world integrity region connectedness

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