To reduce emissions, shipping companies are deploying eco-friendly ships, like those powered by LNG or methanol. Unlike traditional fuels, LNG bunkering is available at a limited number of ports. At the same time, tra...
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To reduce emissions, shipping companies are deploying eco-friendly ships, like those powered by LNG or methanol. Unlike traditional fuels, LNG bunkering is available at a limited number of ports. At the same time, tramp or bulk ships have fewer ports of call on their shipping lines, which may necessitate LNGfueled ships sailing to alternative bunkering ports for refueling. The selection of bunkering ports impacts the operating costs of shipping lines due to differences in fuel prices and geographical locations. Moreover, it must factor in ship speed limits to meet loading and unloading schedules. To optimize the shipping route, speeds, and bunkering plan for LNG-fueled tramp ships, we develop an arc-based mixed-integer linear programming model with the objective of minimizing total operation costs. Subsequently, we propose a leg -based formulation based on the predetermined port call orders. Finally, case studies are conducted to demonstrate the effectiveness and efficiency of the models. Experimental results indicate that the bunkering mode with alternative bunkering ports effectively reduces total operating costs without altering the total voyage time, particularly with substantial differences in fuel prices between ports.
A new flexibility index algorithm for systems under uncertainty and represented by quadratic inequalities is presented. Inspired by the outer-approximation algorithm for convex mixed-integer nonlinear programming, a s...
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A new flexibility index algorithm for systems under uncertainty and represented by quadratic inequalities is presented. Inspired by the outer-approximation algorithm for convex mixed-integer nonlinear programming, a similar iterative strategy is developed. The subproblem, which is a nonlinear program, is constructed by fixing the vertex directions since this class of systems is proved to have a vertex solution if the entries on the diagonal of the Hessian matrix are non-negative. By overestimating the nonlinear constraints, a linear min-max problem is formulated. By dualizing the inner maximization problem, and introducing new variables and constraints, the master problem is reformulated as a mixed-integer linear program. By iteratively solving the subproblem and master problem, the algorithm can be guaranteed to converge to the flexibility index. Numerical examples including a heat exchanger network, a process network, and a unit commitment problem are presented to illustrate the computational efficiency of the algorithm. (c) 2018 American Institute of Chemical Engineers AIChE J, 64: 2486-2499, 2018
A path planning problem for a heterogeneous vehicle is considered. Such a vehicle consists of two parts which have the ability to move individually, but one of them has a shorter range and is therefore required to kee...
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A path planning problem for a heterogeneous vehicle is considered. Such a vehicle consists of two parts which have the ability to move individually, but one of them has a shorter range and is therefore required to keep in a close distance to the main vehicle. The objective is to devise an optimal path of minimal length under the condition that at least one part of the heterogeneous system visits all desired waypoints exactly once. Two versions of the problem are considered. One assumes that the order in which the waypoints are visited is known a priori. In such a case we show that the optimal path can be found by solving a mixed-integer second-order cone problem. The second version assumes that the order in which the waypoints are visited is not known a priori, but can be optimized so as to shorten the length of the path. Two approaches to solve this problem are presented and evaluated with respect to computational complexity.
Hospitals continue to face the challenge of providing high-quality patient care in an environment of rising healthcare costs. In response, a great deal of attention has been given to advance planning decisions such as...
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Hospitals continue to face the challenge of providing high-quality patient care in an environment of rising healthcare costs. In response, a great deal of attention has been given to advance planning decisions such as nurse staffing, bed mix, scheduling, and patient flow. However, less attention has been given to incorporating quick-response methods in the nurse scheduling process by both anticipating and responding to patient demand fluctuations. Therefore, in this paper, we present a model that incorporates two classes of quick-response decisions in hospitals' nurse scheduling: (i) adjustments to the unit assignments of cross-trained float nurses and (ii) transfers of patients between units and off-unit admissions. Analyzing three hospitals that are subject to different regulations with respect to patient-to-nurse ratios allows us to draw conclusions on how these hotly debated ratios impact hospital performance, nurse workload, and patient experience. We find that quick-response via cross-trained nurses may lead to higher total costs in settings where an upper limit on patient-to-nurse ratios is enforced. This result has significant managerial and political relevance in locations such as California. Another takeaway is that only a small number of patient transfers or off-unit admissions provides close to the full potential benefit, thus minimizing the negative impact on patient satisfaction and quality of care. Moreover, our proposed scheduling approach reduces the number of undesired assigned shifts. Finally, bed and nurse capacity utilization are shown to be important considerations when determining how and whether to use quick-response methods. (C) 2019 Elsevier B.V. All rights reserved.
In this paper, we study a mixed-integer programming model of the single-level multi-item capacitated lot-sizing problem (MCLSP), which incorporates shared capacity on the production of items for each period throughout...
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In this paper, we study a mixed-integer programming model of the single-level multi-item capacitated lot-sizing problem (MCLSP), which incorporates shared capacity on the production of items for each period throughout a planning horizon. We derive valid bounds on the partial objective function of the MCLSP formulation by solving the first t periods of the problem over a subset of all items, using dynamic programming and integerprogramming techniques. We also develop algorithms for strengthening these valid inequalities by back-lifting techniques. These inequalities can be utilized within a cutting-plane algorithm, in which we perturb the partial objective function coefficients to identify violated inequalities to the MCLSP polytope. Our computational results show that the envelope inequalities are very effective for the MCLSP instances with different capacity and cost characteristics, when compared to the (l, S) inequalities. (C) 2017 Elsevier Ltd. All rights reserved.
Focusing on the HIV-1 subtype B epidemic, the most frequent HIV variant in Brazil, we extend our work on HIV modeling and propose a practical decision-making framework for the design of individualized HIV-1 drug chemo...
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Focusing on the HIV-1 subtype B epidemic, the most frequent HIV variant in Brazil, we extend our work on HIV modeling and propose a practical decision-making framework for the design of individualized HIV-1 drug chemotherapy strategies relying on patient-specific genotyping test data. The methodology is applied to 9 real-world problem instances regarding a set of 15 antiretroviral drugs and a set of 62 amino acid mutations along 45 positions of the HIV-1 pol gene. Optimized strategies are compared with current guidelines from the Brazilian standard HIV/AIDS treatment protocol. Computational results show that distinct optimal treatment strategies are produced for different patients and we conclude that relevant opportunities are to be promptly exploited on an individual basis through a better management of HIV-1 mutations in the long-term, which can be achieved by frequently changing the HAART scheme over time in response to and in anticipation of the emergence of drug-resistant strains. (C) 2013 Elsevier Ltd. All rights reserved.
Existing studies on the permutation flow shop problem (PFSP) commonly assume that jobs are produced on a single line. However, manufacturers may speed up their production by employing multiple lines, where each line p...
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Existing studies on the permutation flow shop problem (PFSP) commonly assume that jobs are produced on a single line. However, manufacturers may speed up their production by employing multiple lines, where each line produces sub-parts of the final product;which must be assembled by a synchronization machine. This study presents a novel reinforcement learning (RL) approach for the PFSP with multiple lines and demand plans. Our approach differs from existing RL-based scheduling methods as we train the policy to directly generate the sequence in an iterative way, where actions denote the job type to be sequenced next. During cutoff time, we follow a multistart approach that generates sequences with the trained policy, which are subsequently optimized by local search. Our numerical evaluation based on 1050 problem instances with up to three production lines shows that our approach outperforms existing methods on the multi-line problems for short cutoff times, while there is a tie with existing methods for medium and long cutoff times. A further analysis suggests that our approach can also be applied to problems with imbalanced demand plans. (c) 2021 Elsevier B.V. All rights reserved.
We give a new mixedintegerprogramming (MIP) formulation for the quadratic cost partition problem that is derived from a MIP formulation for maximizing a submodular function, Several classes of valid inequalities for...
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We give a new mixedintegerprogramming (MIP) formulation for the quadratic cost partition problem that is derived from a MIP formulation for maximizing a submodular function, Several classes of valid inequalities for the convex hull of the feasible solutions are derived using the valid inequalities for the node packing polyhedron. Facet defining conditions and separation algorithms are discussed and computational results are reported.
The Master Surgery Scheduling problem consists of finding a suitable allocation of operating resources to surgical groups. A myriad of variants of the problem has been addressed in literature. Here we focus on two maj...
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The Master Surgery Scheduling problem consists of finding a suitable allocation of operating resources to surgical groups. A myriad of variants of the problem has been addressed in literature. Here we focus on two major variants, arising during a cooperation with Sykehuset Asker og B'rum HF, a large hospital in the city of Oslo. The first variant asks for balancing patient queue lengths among different specialties, whereas the second for minimizing resort to overtime. To cope with these problems we introduce a new mixedinteger linear formulation and show its beneficial properties. Both problems require the estimation of demand levels. As such estimation is affected by uncertainty, we also develop a light robustness approach to the second variant. Finally we present computational results on a number of real-world instances provided by our reference hospital.
This article presents a novel algorithm for the generation of multiple shortterm production schedules for an open-pit mine, in which several objectives, of varying priority, characterize the quality of each solution. ...
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This article presents a novel algorithm for the generation of multiple shortterm production schedules for an open-pit mine, in which several objectives, of varying priority, characterize the quality of each solution. A shortterm schedule selects regions of a mine site, known as 'blocks', to be extracted in each week of a planning horizon (typically spanning 13 weeks). Existing tools for constructing these schedules use greedy heuristics, with little optimization. To construct a single schedule in which infrastructure is sufficiently utilized, with production grades consistently close to a desired target, a planner must often run these heuristics many times, adjusting parameters after each iteration. A planner's intuition and experience can evaluate the relative quality and mineability of different schedules in a way that is difficult to automate. Of interest to a short-term planner is the generation of multiple schedules, extracting available ore and waste in varying sequences, which can then be manually compared. This article presents a tool in which multiple, diverse, short-term schedules are constructed, meeting a range of common objectives without the need for iterative parameter adjustment.
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