Many patients face difficulties when accessing medical facilities, particularly in rural areas. To alleviate these concerns, medical centers may offer transportation to eligible patients. However, the operation of suc...
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Many patients face difficulties when accessing medical facilities, particularly in rural areas. To alleviate these concerns, medical centers may offer transportation to eligible patients. However, the operation of such services is typically not tightly coordinated with the scheduling of medical appointments. Motivated by our collaborations with the U.S. Veterans Health Administration, we propose an integrated approach that simultaneously considers patient routing and operating room scheduling decisions. We model this problem as a mixed-integer program. Unfortunately, realistically sized instances of this problem are intractable, so we focus on a special case of the problem that captures the needs of low-volume (e.g., rural) hospitals. We establish structural properties that are exploited to develop a branch-and-price algorithm, which greatly outperforms a commercial solver on the original formulation. We discuss several algorithmic strategies to improve the overall solution efficiency. We evaluate the performance of the proposed approach through an extensive computational study calibrated with clinical data. Our results demonstrate that there exist opportunities for healthcare providers to significantly improve the quality of their services by integrating scheduling and routing decisions.
Reindeer husbandry and commercial forestry seek to co-exist in the forests of Northern Sweden. As interwoven as the two industries are, conflicts have arisen. Forest practices have reduced the distribution of lichen, ...
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Reindeer husbandry and commercial forestry seek to co-exist in the forests of Northern Sweden. As interwoven as the two industries are, conflicts have arisen. Forest practices have reduced the distribution of lichen, the main winter diet for reindeer. Forest practices have also increased forest density, compromising the animals' ability to pass through forested areas on their migration routes. In an attempt to reduce impacts on reindeer husbandry, we present a spatially explicit harvest scheduling model that includes reindeer corridors with user-defined spatial characteristics. We illustrate the model in a case study and explore the relationship between timber revenues and the selection and maintenance of reindeer corridors. The corridors are not only to include sufficient lichen habitat, but they are also supposed to ensure access for reindeer by connecting lichen areas with linkages that allow unobstructed travel. Since harvest scheduling occurs over a planning horizon, the spatial configuration of corridors can change from one time period to the next in order to accommodate harvesting activities. Our results suggest that maintaining reindeer corridors in harvest scheduling can be done at minimal cost. Also, we conclude that including corridor constraints in the harvest scheduling model is critical to guarantee connectivity of reindeer pastures.
This study focuses on the optimization of a refinery scheduling process with the help of an adiabatic quantum computer, and more concretely one of the quantum annealers developed by D-Wave Systems. We present an algor...
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This study focuses on the optimization of a refinery scheduling process with the help of an adiabatic quantum computer, and more concretely one of the quantum annealers developed by D-Wave Systems. We present an algorithm for finding a global optimal solution of a MILP that leans on a solver for QUBO problems, and apply it to various possible cases of refinery scheduling optimization. We analyze the inconveniences found during the whole process, whether due to the heuristic nature of D-Wave or the implications of reducing a MILP to QUBO, and present some experimental results.
The inventory-routing problem (IRP) is a typical logistics optimisation problem that supply chains, implementing vendor managed inventory (VMI), are confronted with. It combines inventory control and vehicle routing. ...
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The inventory-routing problem (IRP) is a typical logistics optimisation problem that supply chains, implementing vendor managed inventory (VMI), are confronted with. It combines inventory control and vehicle routing. The main objective of the IRP is to jointly determine optimal quantities of the product to be delivered to the retailers, delivery periods and optimal vehicle routes for the shipment of these quantities. This paper considers a multiperiod inventory-routing problem with stochastic stationary demand rates (MP-SIRP). The problem is first formulated as a linear mixed-integer stochastic program for which we propose a deterministic equivalent approximation model (MP-DAIRP(alpha)). This latter model can be decomposed into two well-know subproblems: an inventory allocation subproblem and a vehicle routing subproblem. The stochastic aspect of the demand is accounted for in the inventory allocation subproblem. The vehicle routing subproblem is solved as a deterministic mixed-integer problem. Lagrangian relaxation is used to determine close to optimal feasible solutions for the MP-DAIRP(alpha). Results of the proposed Lagrangian relaxation approach on some numerical examples are reported and thoroughly discussed.
In this article we address the production planning of parallel multiproduct batch reactors with sequence-dependent changeovers, a challenging problem that has been motivated by a real-world application of a specialty ...
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In this article we address the production planning of parallel multiproduct batch reactors with sequence-dependent changeovers, a challenging problem that has been motivated by a real-world application of a specialty chemicals business. We propose two production planning models that anticipate the impact of the changeovers in this batch processing problem. The first model is based on underestimating the effects of the changeovers that leads to an MILP problem of moderate size. The second model incorporates sequencing constraints that yield very accurate predictions, but at the expense of a larger MILP problem. To solve large scale problems in terms of number of products and reactors, or length of the time horizon, we propose a decomposition technique based on rolling horizon scheme and also a relaxation of the detailed planning model. Several examples are presented to illustrate the performance of the proposed models. (C) 2007 American Institute of Chemical Engineers.
Many practical optimal control problems include discrete decisions. These may be either time-independent parameters or time-dependent control functions as gears or valves that can only take discrete values at any give...
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Many practical optimal control problems include discrete decisions. These may be either time-independent parameters or time-dependent control functions as gears or valves that can only take discrete values at any given time. While great progress has been achieved in the solution of optimization problems involving integer variables, in particular mixed-integer linear programs, as well as in continuous optimal control problems, the combination of the two is yet an open field of research. We consider the question of lower bounds that can be obtained by a relaxation of the integer requirements. For general nonlinear mixed-integer programs such lower bounds typically suffer from a huge integer gap. We convexify (with respect to binary controls) and relax the original problem and prove that the optimal solution of this continuous control problem yields the best lower bound for the nonlinear integer problem. Building on this theoretical result we present a novel algorithm to solve mixed-integer optimal control problems, with a focus on discrete-valued control functions. Our algorithm is based on the direct multiple shooting method, an adaptive refinement of the underlying control discretization grid and tailored heuristic integer methods. Its applicability is shown by a challenging application, the energy optimal control of a subway train with discrete gears and velocity limits.
We study the mixing inequalities that were introduced by Gunluk and Pochet [ Math. Program., 90 (2001), pp. 429-457]. We show that a mixing inequality which mixes n MIR inequalities has MIR rank at most n if it is a t...
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We study the mixing inequalities that were introduced by Gunluk and Pochet [ Math. Program., 90 (2001), pp. 429-457]. We show that a mixing inequality which mixes n MIR inequalities has MIR rank at most n if it is a type I mixing inequality and at most n - 1 if it is a type II mixing inequality. We also show that these bounds are tight for n = 2. Given a mixed-integer set P(I) = P boolean AND Z(I), where P is a polyhedron and Z(I) = {x is an element of R(n) : x(i) is an element of Z for all(i) is an element of I}, we define mixing inequalities for PI. We show that the elementary mixing closure of P with respect to I can be described using a bounded number of mixing inequalities, each of which has a bounded number of terms. This implies that the elementary mixing closure of P is a polyhedron. Finally, we show that any mixing inequality can be derived via a polynomial length MIR cutting-plane proof. Combined with results of Dash [On the complexity of cutting plane proofs using split cuts, IBM Research Report RC 24082, Oct. 2006] and Pudlak [J. Symbolic Logic, 62 (1997), pp. 981-998], this implies that there are valid inequalities for a certain mixed-integer set that cannot be obtained via a polynomial-size mixing cutting-plane proof.
This article develops an experimental platform to select production planning policy in demand-driven wood remanufacturing industry. This industry is characterised by divergent co-production, alternative processes, a m...
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This article develops an experimental platform to select production planning policy in demand-driven wood remanufacturing industry. This industry is characterised by divergent co-production, alternative processes, a make-to-order philosophy and short order cycle times. Under such complex characteristics, the selection of an efficient production plan is a complex task. Previous work has failed to address all the industrial characteristics encountered in wood remanufacturing mills. After defining key performance indicators (KPIs) to measure the production plan efficiency, our methodology uses a periodic re-planning strategy based on a rolling horizon. Then, mixed-integer programming models are formulated leading to different planning approaches. Finally, the resulting decision framework is experimented to prescribe the best planning policy based on the selected KPI. Each production planning is characterised by its planning approach and factors related to the re-planning interval and the planning horizon length. Simulations are conducted using multiple best subset selections combined with an experimental design approach. Using industrial data from a wood remanufacturing mill in Eastern Canada, results indicate that the manufacturing mill should use a planning approach that minimises cost, while utilising the full system capacity. Results also quantify the benefit of using lower re-planning intervals and higher planning horizons.
One of the key fundamentals for organizations to remain competitive in the present economic climate is to effectively manage their supply chains under uncertainty. The notion of supply chain flexibility attempts to ch...
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One of the key fundamentals for organizations to remain competitive in the present economic climate is to effectively manage their supply chains under uncertainty. The notion of supply chain flexibility attempts to characterize the ability of a supply chain to perform satisfactorily in the face of uncertainty. However, limited quantitative analysis is available. In this work, we utilize a flexibility analysis framework developed within the context of process operations and design to characterize supply chain flexibility. This framework also provides a quantitative mapping to various types of flexibility discussed in the operations research and management science literature. Two case studies are included to illustrate the application of this framework for analyzing the flexibility of existing supply chain processes, as well as utilizing it in supply chain design. (C) 2015 Elsevier Ltd. All rights reserved.
In this work we propose two formulations based on Support Vector Machines for simultaneous classification and feature selection that explicitly incorporate attribute acquisition costs. This is a challenging task for t...
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In this work we propose two formulations based on Support Vector Machines for simultaneous classification and feature selection that explicitly incorporate attribute acquisition costs. This is a challenging task for two main reasons: the estimation of the acquisition costs is not straightforward and may depend on multivariate factors, and the inter-dependence between variables must be taken into account for the modelling process since companies usually acquire groups of related variables rather than acquiring them individually. mixed-integer linear programming models are proposed for constructing classifiers that constrain acquisition costs while classifying adequately. Experimental results using credit scoring datasets demonstrate the effectiveness of our methods in terms of predictive performance at a low cost compared to well-known feature selection approaches. (C) 2017 Elsevier B.V. All rights reserved.
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