This study investigates the computer-regulated propofol administration in anesthesia during medical interventions considering output feedback and robust PID control. The paper applies the Affine Tensor Product Model T...
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This study investigates the computer-regulated propofol administration in anesthesia during medical interventions considering output feedback and robust PID control. The paper applies the Affine Tensor Product Model Transformation to derive the appropriate polytopic quasi-LPV representation of the closed-loop dynamics. This model form enables the use of LMI-based optimisation techniques to evaluate the closed loop performance. Despite the highly non-convex nature of this output feedback problem, the PID gains can be locally tuned through simplex optimisation. The proposed method provides a systematic way of tuning PIDcontrolled propofol administration for individual patients with theoretically established worst case performance measures. (C) 2018, IFAC (International Federation of Automatic control) Hosting by Elsevier Ltd. All rights reserved.
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