咨询与建议

限定检索结果

文献类型

  • 1,048 篇 期刊文献
  • 80 篇 资讯
  • 13 篇 会议
  • 6 篇 学位论文

馆藏范围

  • 1,147 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 717 篇 理学
    • 631 篇 生物学
    • 32 篇 化学
    • 8 篇 数学
    • 6 篇 统计学(可授理学、...
    • 5 篇 生态学
    • 3 篇 物理学
  • 470 篇 医学
    • 281 篇 临床医学
    • 215 篇 基础医学(可授医学...
    • 78 篇 药学(可授医学、理...
    • 18 篇 公共卫生与预防医...
    • 16 篇 中西医结合
    • 13 篇 医学技术(可授医学...
    • 7 篇 口腔医学
  • 251 篇 工学
    • 72 篇 生物工程
    • 61 篇 化学工程与技术
    • 18 篇 计算机科学与技术...
    • 15 篇 生物医学工程(可授...
    • 12 篇 材料科学与工程(可...
    • 10 篇 环境科学与工程(可...
    • 5 篇 食品科学与工程(可...
    • 4 篇 电气工程
    • 2 篇 冶金工程
    • 2 篇 水利工程
  • 228 篇 农学
    • 110 篇 作物学
    • 3 篇 畜牧学
  • 9 篇 管理学
    • 8 篇 公共管理
  • 4 篇 教育学
    • 2 篇 心理学(可授教育学...
    • 1 篇 教育学
  • 2 篇 法学
    • 2 篇 社会学
  • 1 篇 经济学
    • 1 篇 应用经济学
  • 1 篇 艺术学

主题

  • 1,147 篇 noncoding rna
  • 134 篇 microrna
  • 88 篇 epigenetics
  • 77 篇 mirna
  • 72 篇 dna methylation
  • 71 篇 lncrna
  • 55 篇 cancer
  • 48 篇 biomarker
  • 46 篇 long noncoding r...
  • 42 篇 circular rna
  • 37 篇 gene regulation
  • 37 篇 histone modifica...
  • 34 篇 rna-seq
  • 33 篇 chromatin
  • 32 篇 circrna
  • 30 篇 pcr
  • 30 篇 transcription
  • 29 篇 gene expression
  • 26 篇 ncrna
  • 24 篇 small rna

机构

  • 10 篇 yale univ dept m...
  • 9 篇 yale univ dept m...
  • 8 篇 yale univ howard...
  • 6 篇 massachusetts ge...
  • 5 篇 russian acad sci...
  • 5 篇 royal coll surge...
  • 5 篇 shahid beheshti ...
  • 5 篇 univ texas md an...
  • 4 篇 collaborat innov...
  • 4 篇 univ leipzig int...
  • 4 篇 shahid beheshti ...
  • 4 篇 shahid beheshti ...
  • 4 篇 univ colorado de...
  • 4 篇 univ toronto dep...
  • 4 篇 univ zurich swis...
  • 4 篇 yale univ dept m...
  • 4 篇 inst hlth carlos...
  • 4 篇 yale univ howard...
  • 3 篇 univ leipzig int...
  • 3 篇 univ wisconsin d...

作者

  • 14 篇 breaker ronald r...
  • 12 篇 henshall david c...
  • 11 篇 vogel joerg
  • 8 篇 harris kimberly ...
  • 8 篇 nakagawa shinich...
  • 7 篇 stadler peter f.
  • 7 篇 ghafouri-fard so...
  • 7 篇 lee jeannie t.
  • 6 篇 de gonzalo-calvo...
  • 6 篇 hirose tetsuro
  • 6 篇 kanduri chandras...
  • 6 篇 zhuang shi-mei
  • 5 篇 steitz joan a.
  • 5 篇 mattick john s.
  • 5 篇 rosenow felix
  • 5 篇 bauer sebastian
  • 5 篇 morris gareth
  • 5 篇 khalilian sheyda
  • 5 篇 gruber andreas r...
  • 5 篇 brennan gary p.

语言

  • 1,078 篇 英文
  • 51 篇 其他
  • 11 篇 荷兰文
  • 4 篇 中文
  • 3 篇 德文
  • 3 篇 俄文
  • 2 篇 法文
  • 1 篇 意大利文
检索条件"主题词=Noncoding RNA"
1147 条 记 录,以下是91-100 订阅
排序:
Epigenetic modulations of noncoding rna: a novel dimension of Cancer biology
收藏 引用
MOLECULAR CANCER 2020年 第1期19卷 64-64页
作者: Yang, Xiao Liu, Ming Li, Mengmeng Zhang, Sen Hiju, Hong Sun, Jing Mao, Zhihai Zheng, Minhua Feng, Bo Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Gen SurgDiv Gastrointestinal & Colorectal S Shanghai 200205 Peoples R China Shanghai Jiao Tong Univ Sch Med Tongren Hosp Dept Genecol & Obstet Shanghai 200205 Peoples R China Tongji Univ Sch Med Shanghai Peoples Hosp 10 Shanghai 200205 Peoples R China
Empowered by recent advances of sequencing techniques, transcriptome-wide studies have characterized over 150 different types of post-transcriptional chemical modifications of rna, ranging from methylations of single ... 详细信息
来源: 评论
Photoperiod-and thermo-sensitive genic male sterility in rice are caused by a point mutation in a novel noncoding rna that produces a small rna
收藏 引用
细胞研究(英文版) 2012年 第4期22卷 649-660页
作者: Hai Zhou Qinjian Liu Jing Li Dagang Jiang Lingyan Zhou Ping Wu Sen Lu Feng Li Liya Zhu Zhenlan Liu Letian Chen Yao-Guang Liu Chuxiong Zhuang State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life Sciences South China Agricultural University Guangzhou Guangdong 510642 China Zhongkai University of Agriculture and Engineering Guangzhou Guangdong 510225 China
Photoperiod- and thermo-sensitive genic male sterility (PGMS and TGMS) are the core components for hybrid breeding in crops. Hybrid rice based on the two-line system using PGMS and TGMS lines has been successfully dev... 详细信息
来源: 评论
Structure of noncoding rna is a determinant of function of rna binding proteins in transcriptional regulation
收藏 引用
CELL AND BIOSCIENCE 2012年 第1期2卷 1-1页
作者: Oyoshi, Takanori Kurokawa, Riki Saitama Med Univ Div Gene Struct Hidaka Saitama 3501241 Japan Saitama Med Univ Funct Res Ctr Genom Med Hidaka Saitama 3501241 Japan Shizuoka Univ Grad Sch Sci Fac Sci Dept Chem Shizuoka 4228529 Japan
The majority of the noncoding regions of mammalian genomes have been found to be transcribed to generate noncoding rnas (ncrnas), resulting in intense interest in their biological roles. During the past decade, numero... 详细信息
来源: 评论
CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding rna
收藏 引用
JOUrnaL OF BIOLOGICAL CHEMISTRY 2021年 第4期297卷 101213-101213页
作者: Ishikura, Shuhei Yoshida, Kazumasa Hashimoto, Sayuri Nakabayashi, Kazuhiko Tsunoda, Toshiyuki Shirasawa, Senji Fukuoka Univ Dept Cell Biol Fac Med Fukuoka Japan Fukuoka Univ Ctr Adv Mol Med Fukuoka Japan Natl Res Inst Child Hlth & Dev Dept Maternal Fetal Biol Tokyo Japan
The centromere is a chromosomal locus that is essential for the accurate segregation of chromosomes during cell division. Transcription of noncoding rna (ncrna) at the centromere plays a crucial role in centromere fun... 详细信息
来源: 评论
Death domain-associated protein DAXX regulates noncoding rna transcription at the centromere through the transcription regulator ZFAT
收藏 引用
JOUrnaL OF BIOLOGICAL CHEMISTRY 2022年 第11期298卷 102528页
作者: Ishikura, Shuhei Yoshida, Kazumasa Tsunoda, Toshiyuki Shirasawa, Senji Fukuoka Univ Fac Med Dept Cell Biol Fukuoka Japan Fukuoka Univ Res Inst Adv Mol Med Fukuoka Japan
The centromere is an essential chromosomal structure for faithful chromosome segregation during cell division. No protein-coding genes exist at the centromeres, but centromeric DNA is actively transcribed into noncodi... 详细信息
来源: 评论
Towards a comprehensive pipeline to identify and functionally annotate long noncoding rna (lncrna)
收藏 引用
COMPUTERS IN BIOLOGY AND MEDICINE 2020年 127卷 104028-104028页
作者: Ramakrishnaiah, Yashpal Kuhlmann, Levin Tyagi, Sonika Monash Univ Fac Informat Technol Clayton Vic 3800 Australia Monash Univ Sch Biol Sci Clayton Vic 3800 Australia Monash Univ Monash eRes Ctr Clayton Vic 3800 Australia
Long noncoding rnas (lncrnas) are implicated in various genetic diseases and cancer, attributed to their critical role in gene regulation. They are a divergent group of rnas and are easily differentiated from other ty... 详细信息
来源: 评论
Advances and challenges in studying noncoding rna regulation of drug metabolism and development of rna therapeutics
收藏 引用
BIOCHEMICAL PHARMACOLOGY 2019年 169卷 113638-000页
作者: Ning, Baitang Yu, Dianke Yu, Ai-Ming US FDA Natl Ctr Toxicol Res Jefferson AR 72079 USA Qingdao Univ Sch Publ Hlth Qingdao Peoples R China Univ Calif Davis Dept Biochem & Mol Med Sch Med 2700 Stockton BlvdSuite 2132 Sacramento CA 95817 USA
Accumulating evidence has demonstrated that genome-derived noncoding rnas (ncrnas) play important roles in modulating inter-individual variations observed in drug metabolism and disposition by controlling the expressi... 详细信息
来源: 评论
The striatal long noncoding rna Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo
收藏 引用
NEUROBIOLOGY OF AGING 2015年 第3期36卷 1601.e7-1601.e16页
作者: Francelle, Laetitia Galvan, Laurie Gaillard, Marie-Claude Petit, Fanny Bernay, Benoit Guillermier, Martine Bonvento, Gilles Dufour, Noelle Elalouf, Jean-Marc Hantraye, Philippe Deglon, Nicole de Chaldee, Michel Brouillet, Emmanuel CEA DSV I2BM Mol Imaging Res Ctr MIRCen F-92265 Fontenay Aux Roses France Univ Paris 11 UMR 9199 Neurodegenerat Dis Lab CEACNRS Fontenay Aux Roses France CEA iBiTecS Gif Sur Yvette France CNRS FRE 3377 Gif Sur Yvette France Univ Paris 11 FRE 3377 Gif Sur Yvette France
A large number of gene products that are enriched in the striatum have ill-defined functions, although they may have key roles in age-dependent neurodegenerative diseases affecting the striatum, especially Huntington ... 详细信息
来源: 评论
The Long noncoding rna CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
收藏 引用
GASTROENTEROLOGY 2020年 第6期159卷 2146-2195页
作者: Chen, Baoqing Dragomir, Mihnea P. Fabris, Linda Bayraktar, Recep Knutsen, Erik Liu, Xu Tang, Changyan Li, Yongfeng Shimura, Tadanobu Ivkovic, Tina Catela De los Santos, Mireia Cruz Anfossi, Simone Shimizu, Masayoshi Shah, Maitri Y. Ling, Hui Shen, Peng Multani, Asha S. Pardini, Barbara Burks, Jared K. Katayama, Hiroyuki Reineke, Lucas C. Huo, Longfei Syed, Muddassir Song, Shumei Ferracin, Manuela Oki, Eiji Fromm, Bastian Ivan, Cristina Bhuvaneshwar, Krithika Gusev, Yuriy Mimori, Koshi Menter, David Sen, Subrata Matsuyama, Takatoshi Uetake, Hiroyuki Vasilescu, Catalin Kopetz, Scott Parker-Thornburg, Jan Taguchi, Ayumu Hanash, Samir M. Girnita, Leonard Slaby, Ondrej Goel, Ajay Varani, Gabriele Gagea, Mihai Li, Chunlai Ajani, Jaffer A. Calin, George A. Univ Texas MD Anderson Canc Ctr Dept Expt Therapeut Houston TX 77030 USA Sun Yat Sen Univ State Key Lab Oncol South China Collaborat Innovat Ctr Canc Med Dept Radiat OncolCanc Ctr Guangzhou Guangdong Peoples R China Sichuan Univ West China Hosp Dept Thorac Oncol Canc Ctr Chengdu Sichuan Peoples R China Sichuan Univ West China Hosp State Key Lab Biotherapy Chengdu Sichuan Peoples R China Carol Davila Univ Med & Pharm Dept Gen Surg Fundeni Clin Hosp Bucharest Romania Arctic Univ Norway Dept Med Biol Fac Hlth Sci Tromso Norway Xi An Jiao Tong Univ Affiliated Hosp 1 Dept Thorac Surg Xian Peoples R China Univ Washington Dept Chem Seattle WA 98195 USA Ctr Gastrointestinal Res Dallas TX USA Baylor Univ Med Ctr Baylor Scott & White Res Inst Ctr Translat Genom & OncolCharles Sammons Canc C Dallas TX USA Masaryk Univ Cent European Inst Technol Brno Czech Republic Southern Med Univ Nanfang Hosp Dept Oncol Guangzhou Peoples R China Univ Texas MD Anderson Canc Ctr Dept Genet Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Leukemia Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Clin Canc Prevent Houston TX 77030 USA Baylor Coll Med Dept Neurosci Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Gastrointestinal Med Oncol Houston TX 77030 USA Univ Bologna Dept Expt Diagnost & Specialty Med Bologna Italy Kyushu Univ Grad Sch Med Sci Dept Surg & Sci Fukuoka Japan Stockholm Univ Wenner Gren Inst Dept Mol Biosci Sci Life Lab Stockholm Sweden Oslo Univ Hosp Norwegian Radium Hosp Inst Canc Res Dept Tumor Biol Oslo Norway Univ Texas MD Anderson Canc Ctr Ctr RNA Interference & Noncoding RNAs Houston TX 77030 USA Georgetown Univ Innovat Ctr Biomed Informat Washington DC USA Kyushu Univ Beppu Hosp Dept Surg Beppu Oita Japan Univ Texas MD Anderson Canc Ctr Dept Translat Mol Pathol Houston TX 77030 USA Tokyo Med & Dent Univ Grad Sch Med Dept Gastroenterol Surg Tokyo Japan Tokyo Med & Dent Univ Grad Sch Dept Sp
BACKGROUND & AIMS: Chromosomal instability (CIN) is a carcinogenesis event that promotes metastasis and resistance to therapy by unclear mechanisms. Expression of the colon cancer-associated transcript 2 gene (CCA... 详细信息
来源: 评论
Long noncoding rna expression in acute lymphoblastic leukemia: A systematic review
收藏 引用
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 2024年 196卷 104290-104290页
作者: Lobo-Alves, Sara Cristina de Oliveira, Liana Alves Kretzschmar, Gabriela Canalli Valengo, Andressa Eloisa Rosati, Roberto Inst Pesquisa Pele Pequeno Principe Av Silva Jardim 1632 BR-80250060 Curitiba PR Brazil Fac Pequeno Principe Av Iguacu 333 BR-80230020 Curitiba PR Brazil Natl Sci & Technol Inst Childrens Canc Biol & Pedi BR-90035003 Porto Alegre RS Brazil Av Silva Jardim 1632 BR-80250060 Curitiba PR Brazil
Long noncoding rnas (lncrnas), as gene expression modulators, are potential players in Acute Lymphoblastic Leukemia (ALL) pathogenesis. We systematically explored current literature on lncrna expression in ALL to iden... 详细信息
来源: 评论