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检索条件"主题词=Noncoding RNA"
1148 条 记 录,以下是431-440 订阅
排序:
Analysis of estrogen-regulated enhancer rnas identifies a functional motif required for enhancer assembly and gene expression
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CELL REPORTS 2022年 第11期39卷 000-000页
作者: Hou, Tim Y. Kraus, W. Lee Univ Texas Southwestern Med Ctr Dallas Cecil H & Ida Green Ctr Reprod Biol Sci Lab Signaling & Gene Regulat 5323 Harry Hines Blvd Dallas TX 75390 USA Univ Texas Southwestern Med Ctr Dallas Dept Obstet & Gynecol Div Basic Res 5323 Harry Hines Blvd Dallas TX 75390 USA
To better understand the functions of non-coding enhancer rnas (ernas), we annotated the estrogen-regulated erna transcriptome in estrogen receptor alpha (ER alpha)-positive breast cancer cells using PRO-cap and rna s... 详细信息
来源: 评论
The whole transcriptome analysis and the circrna-lncrna network construction in arsenic trioxide-treated mice myocardium
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BIOMEDICINE & PHARMACOTHERAPY 2022年 151卷 113183-113183页
作者: Jiang, Yanan Shen, Xiuyun Dong, Chaorun Zhi, Fengnan Gao, Yang Shi, Chunpeng Chao, Yuqiu Xu, Jincheng Shang, Desi Xu, Juan Yang, Baofeng Li, Xia Bai, Yunlong Harbin Med Univ Coll Pharm Dept Pharmacol State Prov Key Labs Biomed Harbin Peoples R China Heilongjiang Acad Med Sci Translat Med Res & Cooperat Ctr Northern China Harbin Peoples R China Harbin Med Univ Coll Bioinformat Sci & Technol Harbin Peoples R China Harbin Med Univ Affiliated Hosp 2 Dept Gastroenterol & Hepatol Harbin Peoples R China Univ South China Affiliated Hosp 1 Hengyang Med Sch Hengyang Hunan Peoples R China
Background/Aims: Arsenic trioxide (ATO) is an effective anti-cancer drug. Nonetheless, it possesses cardiotoxic effects which limit its clinical application. The present study aims to elucidate the molecular basis of ... 详细信息
来源: 评论
C-value paradox: Genesis in misconception that natural selection follows anthropocentric parameters of 'economy' and 'optimum'
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BBA ADVANCES 2023年 4卷 100107页
作者: Lakhotia, Subhash C. Banaras Hindu Univ Inst Sci Dept Zool Cytogenet Lab Varanasi 221005 India
C-value paradox refers to the lack of correlation between biological complexity and the intuitively expected protein-coding genomic information or DNA content. Here I discuss five questions about this paradox: i) Do b... 详细信息
来源: 评论
noncoding rnas: Potential players in the self-renewal of mammalian spermatogonial stem cells
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MOLECULAR REPRODUCTION AND DEVELOPMENT 2018年 第8-9期85卷 720-728页
作者: Bie, Beibei Wang, Ya Li, Liang Fang, Huanle Liu, Libing Sun, Jin Xian Peihua Univ Med Sch Dept Pharm Xian Shaanxi Peoples R China Xi An Jiao Tong Univ Affiliated Hosp 2 Natl & Local Joint Engn Res Ctr Biodiag & Biother 157 West 5th Rd Xian 710004 Shaanxi Peoples R China
Spermatogonial stem cells (SSCs), a unique population of male germ cells with self-renewal ability, are the foundation for maintenance of spermatogenesis throughout the life of the male. Although many regulatory molec... 详细信息
来源: 评论
The epigenetic regulatory mechanisms of ferroptosis and its implications for biological processes and diseases
MEDCOMM
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MEDCOMM 2023年 第3期4卷 e267页
作者: Yang, Molin Luo, Hanshen Yi, Xin Wei, Xiang Jiang, Ding-Sheng Huazhong Univ Sci & Technol Tongji Hosp Tongji Med Coll Div Cardiothorac & Vasc Surg 1095 Jiefang Ave Wuhan 430030 Hubei Peoples R China Wuhan Univ Dept Cardiol Renmin Hosp Wuhan Hubei Peoples R China Minist Educ Key Lab Organ Transplantat Wuhan Hubei Peoples R China NHC Key Lab Organ Transplantat Wuhan Hubei Peoples R China Chinese Acad Med Sci Key Lab Organ Transplantat Wuhan Hubei Peoples R China
Ferroptosis is a form of regulated cell death triggered by the iron-dependent peroxidation of phospholipids. Interactions of iron and lipid metabolism factors jointly promote ferroptosis. Ferroptosis has been demonstr... 详细信息
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Dynamic rna Fitness Landscapes of a Group I Ribozyme during Changes to the Experimental Environment
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MOLECULAR BIOLOGY AND EVOLUTION 2022年 第3期39卷 msab373-msab373页
作者: Peri, Gianluca Gibard, Clementine Shults, Nicholas H. Crossin, Kent Hayden, Eric J. Boise State Univ Biomol Sci Grad Programs Boise ID 83725 USA Boise State Univ Dept Biol Sci Boise ID 83725 USA FACible Biodiagnost 366 SW 5th AveSuite 104 Meridian ID USA
Fitness landscapes of protein and rna molecules can be studied experimentally using high-throughput techniques to measure the functional effects of numerous combinations of mutations. The rugged topography of these mo... 详细信息
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H19 may regulate the immune cell infiltration in carcinogenesis of gastric cancer through miR-378a-5p/SERPINH1 signaling
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WORLD JOUrnaL OF SURGICAL ONCOLOGY 2022年 第1期20卷 295-295页
作者: Li, Jianxin Han, Ting Wang, Xin Wang, Yinchun Chen, Xuan Chen, Wangsheng Yang, Qingqiang Southwest Med Univ Dept Gen Surg Gastrointestinal Surg Affiliated Hosp Luzhou 646000 Sichuan Peoples R China
Background Increasing studies have indicated that noncoding rna (ncrna)-mediated competing endogenous rna (cerna) network serves as a significant role in cancer progression, but the underlying regulatory mechanisms of... 详细信息
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Biogenesis and Regulatory Roles of Circular rnas
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ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY 2022年 第1期38卷 263-289页
作者: Yang, Li Wilusz, Jeremy E. Chen, Ling-Ling Fudan Univ Childrens Hosp Ctr Mol Med Shanghai Peoples R China Fudan Univ Shanghai Key Lab Med Epigenet Int Lab Med Epigenet & Metab Minist Sci & TechnolInst Biomed Sci Shanghai Peoples R China Baylor Coll Med Verna & Marrs McLean Dept Biochem & Mol Biol Therapeut Innovat Ctr Houston TX 77030 USA Chinese Acad Sci Univ Chinese Acad Sci CAS Ctr Excellence Mol Cell SciShanghai Key Lab Shanghai Inst Biochem & Cell BiolState Key Lab M Shanghai Peoples R China ShanghaiTech Univ Sch Life Sci & Technol Shanghai Peoples R China Univ Chinese Acad Sci Sch Life Sci Hangzhou Inst Adv Study Hangzhou Peoples R China
Covalently closed, single-stranded circular rnas can be produced from viral rna genomes as well as from the processing of cellular housekeeping noncoding rnas and precursor messenger rnas. Recent transcriptomic studie... 详细信息
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Whole-transcriptome analysis of periodontal tissue and construction of immune-related competitive endogenous rna network
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BMC ORAL HEALTH 2022年 第1期22卷 370-370页
作者: Zhao, Quanquan Wen, Jing Ouyang, Xiangying Liu, Jianru Liu, Wenyi Zhang, Shengnan Lv, Peiying Lou, Xinzhe Peking Univ Sch & Hosp Stomatol Beijing Key Lab Digital Stomatol Dept PeriodontolNatl Clin Res Ctr Oral DisNatl 22 Zhongguancun South Ave Beijing 100081 Peoples R China
Background In periodontitis, noncoding rnas may play a regulatory role in the immune microenvironment through competitive endogenous rna. We aimed to profile noncoding rna expression and construct immune-related cerna... 详细信息
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Early termination of the Shiga toxin transcript generates a regulatory small rna
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2020年 第40期117卷 25055-25065页
作者: Sy, Brandon M. Lan, Ruiting Tree, Jai J. Univ New South Wales Sch Biotechnol & Biomol Sci Sydney NSW 2052 Australia
Enterohemorrhagic Escherichia coli is a significant human pathogen that causes disease ranging from hemorrhagic colitis to hemolytic uremic syndrome. The latter can lead to potentially fatal renal failure and is cause... 详细信息
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