BackgroundOutbreaks of infectious diseases are a complex phenomenon with many interacting factors. Regional health authorities need prognostic modeling of the epidemic *** these purposes, various mathematical algorith...
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BackgroundOutbreaks of infectious diseases are a complex phenomenon with many interacting factors. Regional health authorities need prognostic modeling of the epidemic *** these purposes, various mathematical algorithms can be used, which are a useful tool for studying the infections spread dynamics. Epidemiological models act as evaluation and prognosis models. The authors outlined the experience of developing a short-term predictive algorithm for the spread of the COVID-19 in the region of the Russian Federation based on the SIR model: Susceptible (vulnerable), Infected (infected), Recovered (recovered). The article describes in detail the methodology of a short-term predictive algorithm, including an assessment of the possibility of building a predictive model and the mathematical aspects of creating such forecast *** show that the predicted results (the mean square of the relative error of the number of infected and those who had recovered) were in agreement with the real-life situation: sigma(I) = 0.0129 and sigma(R) = 0.0058, *** present study shows that despite a large number of sophisticated modifications, each of which finds its scope, it is advisable to use a simple SIR model to quickly predict the spread of coronavirus infection. Its lower accuracy is fully compensated by the adaptive calibration of parameters based on monitoring the current situation with updating indicators in real-time.
Objective This study aimed to develop and validate a predictive algorithm for unsatisfactory response to initial pulmonary arterial hypertension (PAH) therapy using health insurance claims. Methods Adult patients with...
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Objective This study aimed to develop and validate a predictive algorithm for unsatisfactory response to initial pulmonary arterial hypertension (PAH) therapy using health insurance claims. Methods Adult patients with PAH initiated on a first PAH therapy (index date) were identified from Optum's de-identified Clinformatics Data Mart Database (1/1/2010-12/31/2019). A random survival forest algorithm was developed using patient-month data and predicted the "survival function" (i.e. risk of not having unsatisfactory response) over time. For each patient-month observation, risk factors were assessed in the 12 months prior. Unsatisfactory response was defined as the first instance of (1) new PAH therapy, (2) PAH-related hospitalization or emergency room visit, (3) lung transplant or atrial septostomy, (4) PAH-related death or (5) chronic oxygen therapy initiation. To facilitate use in clinical practice, a simplified risk score was also developed based on a linear combination of the most important risk factors identified in the algorithm. Results In total, 4781 patients were included (median age = 69.0 years;58.6% female). Over a median follow-up of 14.0 months, 3169 (66.3%) had an unsatisfactory response. The most important risk factors included in the algorithm were healthcare resource use (i.e. PAH-related outpatient visits, pulmonologist visits, cardiologist visits, all-cause hospitalizations), time since first PAH diagnosis, time since index date, Charlson Comorbidity Index, dyspnea, and age. predictive accuracy was good for the full algorithm (C-statistic: 0.732) but was slightly lower for the simplified risk score (C-statistic: 0.668). Conclusion The present claims-based algorithm performed well in predicting time to unsatisfactory response following initial PAH therapy.
Water scarcity is a pressing global issue that needs to be faced. The United Nations highlights that only about 31 percent of the population is not characterized by water stress, meaning that the world's freshwate...
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Water scarcity is a pressing global issue that needs to be faced. The United Nations highlights that only about 31 percent of the population is not characterized by water stress, meaning that the world's freshwater resources are unevenly distributed and unsustainably managed. This phenomenon is both natural and man-made, as the human footprint is linked to many disciplines, with the largest impact coming from the agricultural sector. Scientific literature highlights how 4.0 technologies are the key drivers to reduce this sector's impact on valuable resources, such as water and soil. Based on these premises, the proposed work aims at improving the irrigation management in agriculture by implementing a three-layer architecture system to optimize water consumption and prevent soil percolation, by avoiding situations where the soil moisture exceeds its capacity point. To achieve this, experimental activities allow the evaluation of the soil capacity point and thus the definition of a confidence interval to guide watering decisions. The latter interval, soil and environmental data, and three-day weather forecasts are aggregate to create a consistent dataset for training and testing three different machine learning algorithms based on a classification problem to predict the state of the irrigation network. As a result, the implemented multi-layer perceptron neural network, support vector machine, and k-neighbors classifier achieved an accuracy of nearly 99%. Despite this, the neural network produced superior decision region boundaries, resulting in fewer false predictions. A Monte Carlo simulation was then applied to evaluate the water and energy savings, which were up to 27 % and 57 %, respectively. In summary, the predictive algorithm-based irrigation management system is a cost-effective solution for optimizing water management in agriculture that it is truly scalable to any crop by assessing the appropriate soil capacity level.
This paper deals with research on the magnetic bearing control systems for a high-speed rotating machine. Theoretical and experimental characteristics of the control systems with the model algorithmic control ( MAC) a...
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This paper deals with research on the magnetic bearing control systems for a high-speed rotating machine. Theoretical and experimental characteristics of the control systems with the model algorithmic control ( MAC) algorithm and the proportional-derivative (PD) algorithm are presented. The MAC algorithm is the non-parametric predictive control method that uses an impulse response model. A laboratory model of the rotor-bearing unit under study consists of two active radial magnetic bearings and one active axial (thrust) magnetic bearing. The control system of the rotor position in air gaps consists of the fast prototyping control unit with a signal processor, the input and output modules, power amplifiers, contactless eddy current sensors and the host PC with dedicated software. Rotor displacement and control current signals were registered during investigations using a data acquisition (DAQ) system. In addition, measurements were performed for various rotor speeds, control algorithms and disturbance signals generated by the control system. Finally, the obtained time histories were presented, analyzed and discussed in this paper.
The temporal error is the main problem for adaptive optical systems operating in the atmosphere. One way to solve this problem is to optimize the adaptive optics system by predictive control algorithms. In study the a...
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ISBN:
(纸本)9781510639423
The temporal error is the main problem for adaptive optical systems operating in the atmosphere. One way to solve this problem is to optimize the adaptive optics system by predictive control algorithms. In study the adaptive optical system installed on the small-aperture telescope with the predictive algorithm are developed. The predictive algorithm uses measurement of center gravity of light intensity at subapertures of the Shack-Hartmann wavefront sensor has been developed. In results it not depends on the type and design of the adaptive mirror. For implementation the Shack-Hartmann wavefront sensor measuring phase distortion, atmospheric turbulence, and transverse wind velocity are created. The design of the wavefront sensor allows replacement of the microlens array with different sizes, focal lengths and operated in wide range of phase aberrations. As a result, the adaptive optics system measure the level of optical atmospheric turbulence for replace the microlens array and it to operated in different turbulent atmospheric conditions.
Objectives: Older veterans prefer to remain in their homes and communities as long as possible. Although targeted delivery of home- and community-based services for veterans might delay long-term care placement, often...
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Objectives: Older veterans prefer to remain in their homes and communities as long as possible. Although targeted delivery of home- and community-based services for veterans might delay long-term care placement, often, access to these services is inconsistently organized or delayed. To aid in early recognition of veterans at high risk for long-term care placement or death, we developed and validated a predictive algorithm, "Choose Home." Design: A retrospective observational cohort analysis was used. Setting and Participants: Two cohorts of Veterans Health Administration (VHA;a large integrated health care system) users were assembled: Derivation (4.6 million) and Confirmation (4.7 million). The Derivation Cohort included Veterans Administration users from fiscal year 2013;the Confirmation Cohort included Veterans Administration users from fiscal year 2014. Methods: A total of 148 predictor variables, including demographics, comorbidities, and utilizations were selected using logistic regression to predict placement in a long-term care facility for >90 days or death within 2 years. Results: Veterans were predominantly male [92.8% (Derivation), 92.5% (Confirmation)] and older [61.7 +/- 15.5 (Derivation), 61.5 +/- 15.6 years (Confirmation)], with a high prevalence of comorbid conditions. Between the Derivation and Confirmation Cohorts, the areas under the receiver operating characteristic curves were found to be 0.80 [95% confidence interval (CI) 0.799, 0.802] and 0.80 (95% CI 0.800, 0.802), respectively, indicating good discrimination for determining at-risk veterans. Conclusions and Implications: We created a predictive algorithm that identifies veterans at highest risk for long-term institutionalization or death. This algorithm provides clinicians with information that can proactively inform clinical decision making and care coordination. This study provides the groundwork for future investigations on how home- and community-based services can target older adults a
Background: Opioid abuse in chronic pain patients is a major public health issue, with rapidly increasing addiction rates and deaths from unintentional overdose more than quadrupling since 1999. Purpose: This study se...
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Background: Opioid abuse in chronic pain patients is a major public health issue, with rapidly increasing addiction rates and deaths from unintentional overdose more than quadrupling since 1999. Purpose: This study seeks to determine the predictability of aberrant behavior to opioids using a comprehensive scoring algorithm incorporating phenotypic risk factors and neuroscience-associated single-nucleotide polymorphisms (SNPs). Patients and methods: The Proove Opioid Risk (POR) algorithm determines the predictability of aberrant behavior to opioids using a comprehensive scoring algorithm incorporating phenotypic risk factors and neuroscience-associated SNPs. In a validation study with 258 subjects with diagnosed opioid use disorder (OUD) and 650 controls who reported using opioids, the POR successfully categorized patients at high and moderate risks of opioid misuse or abuse with 95.7% sensitivity. Regardless of changes in the prevalence of opioid misuse or abuse, the sensitivity of POR remained >95%. Conclusion: The POR correctly stratifies patients into low-, moderate-, and high-risk categories to appropriately identify patients at need for additional guidance, monitoring, or treatment changes.
Background: Opioid abuse in chronic pain patients is a major public health issue. Primary care providers are frequently the first to prescribe opioids to patients suffering from pain, yet do not always have the time o...
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Background: Opioid abuse in chronic pain patients is a major public health issue. Primary care providers are frequently the first to prescribe opioids to patients suffering from pain, yet do not always have the time or resources to adequately evaluate the risk of opioid use disorder (OUD). Purpose: This study seeks to determine the predictability of aberrant behavior to opioids using a comprehensive scoring algorithm ("profile") incorporating phenotypic and, more uniquely, genotypic risk factors. Methods and Results: In a validation study with 452 participants diagnosed with OUD and 1237 controls, the algorithm successfully categorized patients at high and moderate risk of OUD with 91.8% sensitivity. Regardless of changes in the prevalence of OUD, sensitivity of the algorithm remained >90%. Conclusion: The algorithm correctly stratifies primary care patients into low-, moderate-, and high-risk categories to appropriately identify patients in need for additional guidance, monitoring, or treatment changes.
In this paper we propose a predictive alarm ranking algorithm for prevention of nocturnal hypoglycemia (NH) in patients with insulin-treated diabetes. We adapt collaborative filtering method for prognosis of risk of N...
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ISBN:
(纸本)9781538606971
In this paper we propose a predictive alarm ranking algorithm for prevention of nocturnal hypoglycemia (NH) in patients with insulin-treated diabetes. We adapt collaborative filtering method for prognosis of risk of NH occurrence in diabetic patients. We illustrate the proposed algorithm and test it to quantify its accuracy with medical records obtained within the framework of the European FP7-funded project DIAdvisor. Results show that the algorithm with proper ranking and preprocessed data outperforms well-known NH-prediction approaches in terms of sensitivity, specificity and F1-score.
Many robotic applications that are critical for robot performance require immediate feedback, hence execution time is a critical concern. Furthermore, it is common that robots come with a fixed quantity of hardware re...
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ISBN:
(纸本)9781665442077
Many robotic applications that are critical for robot performance require immediate feedback, hence execution time is a critical concern. Furthermore, it is common that robots come with a fixed quantity of hardware resources;if an application requires more computational resources than the robot can accommodate, its onboard execution might be extended to a degree that degrades the robot's performance. Cloud computing, on the other hand, features on-demand computational resources;by enabling robots to leverage those resources, application execution time can be reduced. The key to enabling robot use of cloud computing is designing an efficient offloading algorithm that makes optimum use of the robot's onboard capabilities and also forms a quick consensus on when to offload without any prior knowledge or information about the application. In this paper, we propose a predictive algorithm to anticipate the time needed to execute an application for a given application data input size with the help of a small number of previous observations. To validate the algorithm, we train it on the previous N observations, which include independent (input data size) and dependent (execution time) variables. To understand how algorithm performance varies in terms of prediction accuracy and error, we tested various N values using linear regression and a mobile robot path planning application. From our experiments and analysis, we determined the algorithm to have acceptable error and prediction accuracy when N > 40.
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