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检索条件"主题词=Programming Language"
1151 条 记 录,以下是1041-1050 订阅
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RNA Sequencing in B-Cell Lymphomas
RNA Sequencing in B-Cell Lymphomas
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作者: Da Wei Huang Moez Dawood Calvin A. Johnson Roland Schmitz
High-throughput mRNA sequencing (RNA-Seq) provides both qualitative and quantitative evaluation of the transcriptome. This method uses complementary DNA (cDNA) to generate several millions of short sequence reads that... 详细信息
来源: 评论
From RNA-seq to Biological Inference: Using Compositional Data Analysis in Meta-Transcriptomics
From RNA-seq to Biological Inference: Using Compositional Da...
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作者: Jean M. Macklaim Gregory B. Gloor
The proper analysis of high-throughput sequencing datasets of mixed microbial communities (meta-transcriptomics) is substantially more complex than for datasets composed of single organisms. Adapting commonly used RNA... 详细信息
来源: 评论
SCENIC: single-cell regulatory network inference and clustering
SCENIC: single-cell regulatory network inference and cluster...
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作者: Sara Aibar Carmen Bravo González-Blas Thomas Moerman Vân Anh Huynh-Thu Hana Imrichova Gert Hulselmans Florian Rambow Jean-Christophe Marine Pierre Geurts Jan Aerts Joost van den Oord Zeynep Kalender Atak Jasper Wouters Stein Aerts
We present SCENIC, a computational method for simultaneous gene regulatory network reconstruction and cell-state identification from single-cell RNA-seq data (http://*** ). On a compendium of single-cel... 详细信息
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Statistical Analysis of Post-Translational Modifications Quantified by Label-Free Proteomics Across Multiple Biological Conditions with R: Illustration from SARS-CoV-2 Infected Cells
Statistical Analysis of Post-Translational Modifications Qua...
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作者: Quentin Giai Gianetto
Protein post-translational modifications (PTMs) are essential elements of cellular communication. Their variations in abundance can affect cellular pathways, leading to cellular disorders and diseases. A widely used m... 详细信息
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A Method to Discover Phased siRNA Loci
A Method to Discover Phased siRNA Loci
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作者: Michael J. Axtell
Short, interfering RNAs (siRNAs) arise from the processing of long double-stranded RNA (dsRNA) by Dicer enzymes. Dicers generate siRNA duplexes by successive hydrolysis of both strands of the dsRNA phosphodiester back... 详细信息
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Estimating Global Methylation and Erasure Using Low-Coverage Whole-Genome Bisulfite SequencingBisulfite sequencing (BS-Seq) (WGBS Whole-genome bisulfite sequencing (WGBS) )
Estimating Global Methylation and Erasure Using Low-Coverage...
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作者: Oscar Ortega-Recalde Julian R. Peat Donna M. Bond Timothy A. Hore
Whole-genome bisulfite sequencing (WGBS) is a popular method for characterizing cytosine methylation because it is fully quantitative and has base-pair resolution. While WGBS is prohibitively expensive for experiments... 详细信息
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Annotation of Glycomics MS and MS/MS Spectra Using the GlycoWorkbench Software Tool
Annotation of Glycomics MS and MS/MS Spectra Using the Glyco...
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作者: David Damerell Alessio Ceroni Kai Maass René Ranzinger Anne Dell Stuart M. Haslam
The GlycoWorkbench software tool allows users to semiautomatically annotate glycomics MS and MS/MS spectra and MS glycoproteomics spectra. The GlycanBuilder software tool is embedded within GlycoWorkbench allowing use... 详细信息
来源: 评论
A Practical Guide to Using Structural Variants for Genome-Wide Association Studies
A Practical Guide to Using Structural Variants for Genome-Wi...
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作者: Marc-André Lemay Sidiki Malle
Structural variants (SVs) are known to have large functional impacts on phenotypes of agricultural interest, but they have yet to be routinely used for GWAS. Apart from the difficulty in obtaining high-quality SV geno... 详细信息
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Atomistic Molecular Dynamics Simulations of DNA in Complex 3D Arrangements for Comparison with Lower Resolution Structural Experiments
Atomistic Molecular Dynamics Simulations of DNA in Complex 3...
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作者: George Watson Victor Velasco-Berrelleza Agnes Noy
Atomic-level computer simulations are a very useful tool for describing the structure and dynamics of complex biomolecules such as DNA and for providing detail at a resolution where experimental techniques cannot arri... 详细信息
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Bioinformatic Analysis of Nucleosome and Histone Variant Positioning
Bioinformatic Analysis of Nucleosome and Histone Variant Pos...
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作者: Jakub Mieczkowski Michael Y. Tolstorukov
Assays profiling nucleosome positioning and occupancy are often coupled with high-throughput sequencing, which results in generation of large data sets. These data sets require processing in specialized computational ... 详细信息
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