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检索条件"主题词=Programming Language"
1132 条 记 录,以下是1111-1120 订阅
The SQUAD Method for the Qualitative Modeling of Regulatory Networks
The SQUAD Method for the Qualitative Modeling of Regulatory ...
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作者: Akram Méndez Carlos Ramírez Mauricio Pérez Martínez Luis Mendoza
The wealth of molecular information provided by high-throughput technologies has enhanced the efforts dedicated to the reconstruction of regulatory networks in diverse biological systems. This information, however, ha... 详细信息
来源: 评论
CRISPR/Cas9-Based Chemogenomic Profiling in Mammalian Cells
CRISPR/Cas9-Based Chemogenomic Profiling in Mammalian Cells
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作者: Dominic Hoepfner Gregory McAllister Gregory R. Hoffman
Chemogenomic profiling is a powerful and unbiased approach to elucidate pharmacological targets and the mechanism of bioactive compounds. It is based on identifying cellular hypersensitivity and resistance caused by i... 详细信息
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RNA Sequencing and Quantitation Using the Helicos Genetic Analysis System
RNA Sequencing and Quantitation Using the Helicos Genetic An...
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作者: Tal Raz Marie Causey Daniel R. Jones Alix Kieu Stan Letovsky Doron Lipson Edward Thayer John F. Thompson Patrice M. Milos
The recent transition in gene expression analysis technology to ultra high-throughput cDNA sequencing provides a means for higher quantitation sensitivity across a wider dynamic range than previously possible. Sensiti... 详细信息
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Constructing Computational Pipelines
Constructing Computational Pipelines
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作者: Mark Halling-Brown Adrian J. Shepherd
Many bioinformatics tasks involve creating a computational pipeline from existing software components and algorithms. The traditional approach is to glue components together using scripts written in a programming lang... 详细信息
来源: 评论
Using Deep Sequencing Data for Identification of Editing Sites in Mature miRNAs
Using Deep Sequencing Data for Identification of Editing Sit...
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作者: Shahar Alon Eli Eisenberg
Deep sequencing has many possible applications; one of them is the identification and quantification of RNA editing sites. The most common type of RNA editing is adenosine to inosine (A-to-I) editing. A prerequisite f... 详细信息
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Array-Based Multiplex and High-Throughput Serology Assays
Array-Based Multiplex and High-Throughput Serology Assays
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作者: Jennie Olofsson Ceke Hellström Eni Andersson Jamil Yousef Lovisa Skoglund Ronald Sjöberg Anna Månberg Peter Nilsson Elisa Pin
The detection of antibody responses using serological tests provides means to diagnose infections, follow disease transmission, and monitor vaccination responses. The coronavirus disease 2019 (COVID-19) pandemic, caus... 详细信息
来源: 评论
Gene Regulatory Networks from Single Cell Data for Exploring Cell Fate Decisions
Gene Regulatory Networks from Single Cell Data for Exploring...
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作者: Thalia E. Chan Michael P. Stumpf Ann C. Babtie
Single cell experimental techniques now allow us to quantify gene expression in up to thousands of individual cells. These data reveal the changes in transcriptional state that occur as cells progress through developm... 详细信息
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Insights into Global Mechanisms and Disease by Gene Expression Profiling
Insights into Global Mechanisms and Disease by Gene Expressi...
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作者: Fátima Sánchez-Cabo Johannes Rainer Ana Dopazo Zlatko Trajanoski Hubert Hackl
Transcriptomics has played an essential role as proof of concept in the development of experimental and bioinformatics approaches for the generation and analysis of Omics data. We are giving an introduction on how lar... 详细信息
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Genome-Wide Quantitative Fitness Analysis (QFA) of Yeast Cultures
Genome-Wide Quantitative Fitness Analysis (QFA) of Yeast Cul...
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作者: Eva-Maria Holstein Conor Lawless Peter Banks David Lydall
We provide a detailed protocol for robot-assisted, genome-wide measurement of fitness in the model yeast Saccharomyces cerevisiae using Quantitative Fitness Analysis (QFA). We first describe how we construct thousands... 详细信息
来源: 评论
Inferring Gene Regulatory Networks in the
Inferring Gene Regulatory Networks in the
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作者: Maria Angels Luis Balaguer Rosangela Sozzani
Gene regulatory network (GRN) models have been shown to predict and represent interactions among sets of genes. Here, we first show the basic steps to implement a simple but computationally efficient algorithm to infe... 详细信息
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