检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

500 篇 资讯
286 篇 期刊文献
235 篇 会议
67 册 图书
45 篇 学位论文

馆藏范围

1,133 篇 电子文献
1 种 纸本馆藏

日期分布

学科分类号

460 篇 工学
- 359 篇 计算机科学与技术...
- 191 篇 软件工程
- 118 篇 电气工程
- 52 篇 信息与通信工程
- 43 篇 控制科学与工程
- 13 篇 电子科学与技术（可...
- 11 篇 机械工程
- 8 篇 石油与天然气工程
- 6 篇 材料科学与工程（可...
- 5 篇 仪器科学与技术
- 4 篇 建筑学
- 4 篇 化学工程与技术
- 4 篇 网络空间安全
- 3 篇 力学（可授工学、理...
- 3 篇 动力工程及工程热...
- 3 篇 土木工程
- 3 篇 核科学与技术
- 3 篇 环境科学与工程（可...
59 篇 理学
- 22 篇 数学
- 17 篇 生物学
- 9 篇 物理学
- 5 篇 科学技术史(分学科...
- 4 篇 地球物理学
- 4 篇 系统科学
43 篇 教育学
- 40 篇 教育学
- 4 篇 心理学(可授教育学...
30 篇 管理学
- 24 篇 管理科学与工程(可...
- 5 篇 图书情报与档案管...
7 篇 农学
7 篇 医学
- 4 篇 基础医学(可授医学...
4 篇 法学
- 4 篇 社会学
3 篇 哲学
3 篇 经济学
3 篇 文学
2 篇 历史学

主题

1,133 篇 programming lang...
184 篇 python
180 篇 statistical calc...
168 篇 data analysis
78 篇 homo sapiens
72 篇 cell and tissue ...
68 篇 microarray
66 篇 machine learning
60 篇 pcr
58 篇 matlab
58 篇 rna-seq
58 篇 genomics
49 篇 image analysis
47 篇 programming
47 篇 mass spectrometr...
43 篇 compiler
43 篇 principal compon...
40 篇 proteomics
39 篇 genome visualiza...
39 篇 mus musculus

机构

16 篇 brno university ...
7 篇 charles universi...
6 篇 united states na...
3 篇 univ kebangsaan ...
2 篇 army engn univ p...
2 篇 hebei univ engn ...
2 篇 natl taipei univ...
2 篇 gannon univ dept...
2 篇 nanjing univ sta...
2 篇 college of compu...
2 篇 swiss fed inst t...
2 篇 texas a&m univer...
2 篇 data processing ...
2 篇 verivue
2 篇 univ new mexico ...
2 篇 aalto university
2 篇 politehn univ ti...
2 篇 institut für inf...
2 篇 univ glasgow gla...
2 篇 univ utah salt l...

作者

5 篇 rune matthiesen
4 篇 sharanya manohar...
4 篇 oviya ramalakshm...
4 篇 phillips andrew
3 篇 tshukudu ethel
3 篇 cedric gondro
3 篇 vijaykumar yoges...
3 篇 batmaz firat
3 篇 ana sofia carval...
3 篇 francesca grison...
3 篇 wu di
3 篇 junghyun namkung
3 篇 j. b. brown
3 篇 xu baowen
3 篇 chen lin
3 篇 roeland m. merks
3 篇 laercio r. porto...
3 篇 seung hwan lee
3 篇 christoph bock
3 篇 javier martínez-...

语言

1,092 篇 英文
34 篇 其他
5 篇 中文
1 篇 日文
1 篇 葡萄牙文

检索条件"主题词=Programming Language"

共 1133 条记录，以下是621-630 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

Rapid identification of causal mutations in tomato EMS populations via mapping-by-sequencing

Rapid identification of causal mutations in tomato EMS popul...

引用

作者： Virginie Garcia Cécile Bres Daniel Just Lucie Fernandez Fabienne Wong Jun Tai Jean-Philippe Mauxion Marie-Christine Le Paslier Aurélie Bérard Dominique Brunel Koh Aoki Saleh Alseekh Alisdair R Fernie Paul D Fraser Christophe Rothan

The tomato is the model species of choice for fleshy fruit development and for the Solanaceae family. Ethyl methanesulfonate (EMS) mutants of tomato have already proven their utility for analysis of gene function in plants, leading to improved breeding stocks and superior tomato varieties. However, until recently, the identification of causal mutations that underlie particular phenotypes has been a very lengthy task that many laboratories could not afford because of spatial and technical limitations. Here, we describe a simple protocol for identifying causal mutations in tomato using a mapping-by-sequencing strategy. Plants displaying phenotypes of interest are first isolated by screening an EMS mutant collection generated in the miniature cultivar Micro-Tom. A recombinant F2 population is then produced by crossing the mutant with a wild-type (WT; non-mutagenized) genotype, and F2 segregants displaying the same phenotype are subsequently pooled. Finally, whole-genome sequencing and analysis of allele distributions in the pools allow for the identification of the causal mutation. The whole process, from the isolation of the tomato mutant to the identification of the causal mutation, takes 6–12 months. This strategy overcomes many previous limitations, is simple to use and can be applied in most laboratories with limited facilities for plant culture and genotyping. less

关键词： Genetic Mapping Library Preparation Whole-genome Sequencing Genotyping Agarose Gel Electrophoresis Illumina Sequencing Variant Calling Genome Annotation Mutagenesis DNA Sequencing TruSeq DNA Ligation SAMtools Python programming language Solanum lycopersicum Homo sapiens Next-generation sequencing Plant genetics Plant breeding

来源：评论

学校读者我要写书评

暂无评论

Computational Biology Methods for Characterization of Pluripotent Cells

Computational Biology Methods for Characterization of Plurip...

引用

作者： Marcos J. Araúzo-Bravo

Pluripotent cells are a powerful tool for regenerative medicine and drug discovery. Several techniques have been developed to induce pluripotency, or to extract pluripotent cells from different tissues and biological fluids. However, the characterization of pluripotency requires tedious, expensive, time-consuming, and not always reliable wet-lab experiments; thus, an easy, standard quality-control protocol of pluripotency assessment remains to be established. Here to help comes the use of high-throughput techniques, and in particular, the employment of gene expression microarrays, which has become a complementary technique for cellular characterization. Research has shown that the transcriptomics comparison with an Embryonic Stem Cell (ESC) of reference is a good approach to assess the pluripotency. Under the premise that the best protocol is a computer software source code, here I propose and explain line by line a software protocol coded in R-Bioconductor for pluripotency assessment based on the comparison of transcriptomics data of pluripotent cells with an ESC of reference. I provide advice for experimental design, warning about possible pitfalls, and guides for results interpretation. less

关键词： Transcriptomics Principal Component Analysis Statistical Calculation Next Generation Sequencing MATLAB Microarray programming language Data analysis Mus musculus R iPSC Cellular reprogramming Computational biology Bioconductor Hierarchical clustering Scatterplots

来源：评论

学校读者我要写书评

暂无评论

Ensembl Plants: Integrating Tools for Visualizing, Mining, and Analyzing Plant Genomics Data

Ensembl Plants: Integrating Tools for Visualizing, Mining, a...

引用

作者： Dan Bolser Daniel M. Staines Emily Pritchard Paul Kersey

Ensembl Plants (http://*** ) is an integrative resource presenting genome-scale information for a growing number of sequenced plant species (currently 33). Data provided includes genome sequence, gene models, functional annotation, and polymorphic loci. Various additional information are provided for variation data, including population structure, individual genotypes, linkage, and phenotype data. In each release, comparative analyses are performed on whole genome and protein sequences, and genome alignments and gene trees are made available that show the implied evolutionary history of each gene family. Access to the data is provided through a genome browser incorporating many specialist interfaces for different data types, and through a variety of additional methods for programmatic access and data mining. These access routes are consistent with those offered through the Ensembl interface for the genomes of non-plant species, including those of plant pathogens, pests, and pollinators. Ensembl Plants is updated 4–5 times a year and is developed in collaboration with our international partners in the Gramene (http://*** ) and transPLANT projects (http://*** ). less

关键词： Genomics Transcriptomics Data Mining Genome Visualization RNA-seq Multiple Sequence Alignment Genome Assembly Genome Alignment Ensembl Gramene Database Management System programming language Arabidopsis lyrata Arabidopsis thaliana Chlamydomonas reinhardtii Zea mays Medicago truncatula Setaria italica Physcomitrella patens Populus trichocarpa Populus (cottonwood) Oryza brachyantha Oryza glaberrima Oryza sativa Indica Group Oryza sativa Japonica Group Selaginella moellendorffii Solanum lycopersicum Oryza barthii Oryza punctata Oryza nivara Oryza rufipogon Brassica rapa Solanum tuberosum Prunus Rosaceae Glycine max Triticum aestivum Databases Genome Cereals Phenotype Genetic Crops Comparative genomic Functional genomic

来源：评论

学校读者我要写书评

暂无评论

Introduction to Computer-Assisted Analysis in Hydrocarbon and Lipid Microbiology

Introduction to Computer-Assisted Analysis in Hydrocarbon an...

引用

作者： Wilfred F. Röling

The large datasets generated in the immense complex field of hydrocarbon and lipid microbiology cannot be addressed and understood without computer-assisted analysis. Key components in computer-assisted analysis are bioinformatics, databases, statistics, and mathematical modeling. Computer-assisted analysis contributes to the entire scientific process: experimental design, data analysis, data storage, and utilization of these stored data. A wide range of relevant protocols are presented in this volume: protocols dealing with subjects that are also popular in other research areas and protocols addressing important topics specific for hydrocarbon and lipid microbiology. The basics of a major open-source programming language, Python, will be introduced. less

关键词： Statistical Calculation Mathematical Modeling Data analysis programming language Python Bioinformatics Systems biology Computational biology Mathematical biology

来源：评论

学校读者我要写书评

暂无评论

Analysis of bacterial-surface-specific antibodies in body fluids using bacterial flow cytometry

Analysis of bacterial-surface-specific antibodies in body fl...

引用

作者： Kathrin Moor Jehane Fadlallah Albulena Toska Delphine Sterlin Maria L Balmer Andrew J Macpherson Guy Gorochov Martin Larsen Emma Slack

Antibacterial antibody responses that target surfaces of live bacteria or secreted toxins are likely to be relevant in controlling bacterial pathogenesis. The ability to specifically quantify bacterial-surface-binding antibodies is therefore highly attractive as a quantitative correlate of immune protection. Here, binding of antibodies from various body fluids to pure-cultured live bacteria is made visible with fluorophore-conjugated secondary antibodies and measured by flow cytometry. We indicate the necessary controls for excluding nonspecific binding and also demonstrate a cross-adsorption technique for determining the extent of cross-reactivity. This technique has numerous advantages over standard ELISA and western blotting techniques because of its independence from scaffold binding, exclusion of cross-reactive elements from lysed bacteria and ability to visualize bacterial subpopulations. In addition, less than 105 bacteria and less than 10 μg of antibody are required per sample. The technique requires 3–4 h of hands-on experimentation and analysis. Moreover, it can be combined with automation and mutliplexing for high-throughput applications. less

关键词： Flow Cytometry ELISA Western Blot Microbial Culture Anaerobic Culture Titration Lavage FACS Statistical Calculation PCR Data analysis GraphPad Prism programming language Homo sapiens Ovis aries Mus musculus Equus asinus Capra hircus Saccharomyces cerevisiae Glycine max Immunological techniques Antibodies Bacterial pathogenesis Anti-human Anti-mouse Anti-mouse IgM Anti-mouse IgA

来源：评论

学校读者我要写书评

暂无评论

Agent-Based Modeling of Cancer Stem Cell Driven Solid Tumor Growth

Agent-Based Modeling of Cancer Stem Cell Driven Solid Tumor ...

引用

作者： Jan Poleszczuk Paul Macklin Heiko Enderling

Computational modeling of tumor growth has become an invaluable tool to simulate complex cell–cell interactions and emerging population-level dynamics. Agent-based models are commonly used to describe the behavior and interaction of individual cells in different environments. Behavioral rules can be informed and calibrated by in vitro assays, and emerging population-level dynamics may be validated with both in vitro and in vivo experiments. Here, we describe the design and implementation of a lattice-based agent-based model of cancer stem cell driven tumor growth. less

关键词： Microscopy programming language Python Calibration Cancer stem cell Agent-based model Tumor growth Domain Search order High performance Digital cell line

来源：评论

学校读者我要写书评

暂无评论

Review and Literature Mining on Proteostasis Factors and Cancer

Review and Literature Mining on Proteostasis Factors and Can...

引用

作者： Ana Sofia Carvalho Manuel S. Rodríguez Rune Matthiesen

Automatic analysis of increasingly growing literature repositories including data integration to other databases is a powerful tool to propose hypothesis that can be used to plan experiments to validate or disprove the hypothesis. Furthermore, it provides means to evaluate the redundancy of research line in comparison to the published literature. This is potentially beneficial for those developing research in a specific disease which are interested in exploring a particular pathway or set of genes/proteins. In the scope of the integrating book a case will be made addressing proteostasis factors in cancer. The maintenance of proteome homeostasis, known as proteostasis, is a process by which cells regulate protein translation, degradation, subcellular localization, and protein folding and consists of an integrated network of proteins. The ubiquitin-proteasome system plays a key role in essential biological processes such as cell cycle, DNA damage repair, membrane trafficking, and maintaining protein homeostasis. Cells maintain proteostasis by regulating protein translation, degradation, subcellular localization, and protein folding. Aberrant proteostasis leads to loss-of-function diseases (cystic fibrosis) and gain-of-toxic-function diseases (Alzheimer’s, Parkinson’s, and Huntington’s disease). Cancer therapy on the other hand explores inhibition of proteostasis factors to trigger endoplasmic reticulum stress with subsequent apoptosis. Alternatively therapies target deubiquitinases and thereby regulate tumor promoters or suppressors. Furthermore, mutations in specific proteostasis factors are associated with higher risk for specific cancers, e.g., BRCA mutations in breast cancer. This chapter discusses proteostasis protein factors’ association with cancer from a literature mining perspective. less

关键词： Text Mining Recombinant Protein Expression Data Mining programming language Cancer Proteostasis Wordcloud

来源：评论

学校读者我要写书评

暂无评论

TUBEs-Mass Spectrometry for Identification and Analysis of the Ubiquitin-Proteome

TUBEs-Mass Spectrometry for Identification and Analysis of t...

引用

作者： Mikel Azkargorta Iraide Escobes Felix Elortza Rune Matthiesen Manuel S. Rodríguez

Mass spectrometry (MS) has become the method of choice for the large-scale analysis of protein ubiquitylation. There exist a number of proposed methods for mapping ubiquitin sites, each with different pros and cons. We present here a protocol for the MS analysis of the ubiquitin-proteome captured by TUBEs and subsequent data analysis. Using dedicated software and algorithms, specific information on the presence of ubiquitylated peptides can be obtained from the MS search results. In addition, a quantitative and functional analysis of the ubiquitylated proteins and their interacting partners helps to unravel the biological and molecular processes they are involved in. less

关键词： Collision-induced Dissociation Mass Spectrometry Statistical Calculation Spectroscopy Gel Staining Database Search Spectral Counting Proteomics Liquid Chromatography-mass Spectrometry Functional Enrichment Data analysis programming language Escherichia coli Ubiquitin Posttranslational modification (PTM) Tandem Ubiquitin Binding Entities (TUBEs) Gene Ontology (GO) Iodoacetamide (IAA) Chloroacetamide (CAA)

来源：评论

学校读者我要写书评

暂无评论

A scored human protein–protein interaction network to catalyze genomic interpretation

A scored human protein–protein interaction network to catal...

引用

作者： Taibo Li Rasmus Wernersson Rasmus B Hansen Heiko Horn Johnathan Mercer Greg Slodkowicz Christopher T Workman Olga Rigina Kristoffer Rapacki Hans H Stærfeldt Søren Brunak Thomas S Jensen Kasper Lage

Genome-scale human protein–protein interaction networks are critical to understanding cell biology and interpreting genomic data, but challenging to produce experimentally. Through data integration and quality control, we provide a scored human protein–protein interaction network (InWeb_InBioMap, or InWeb_IM) with severalfold more interactions (>500,000) and better functional biological relevance than comparable resources. We illustrate that InWeb_InBioMap enables functional interpretation of >4,700 cancer genomes and genes involved in autism. less

关键词： Functional Genomics Statistical Calculation Proteomics Immunoprecipitation Ensembl programming language Pull-down Assay Homo sapiens Protein–protein interaction networks Systems biology Literature mining Protein databases

来源：评论

学校读者我要写书评

暂无评论

In Vitro and In Vivo Imaging of Fluorescent Aptamers

In Vitro and In Vivo Imaging of Fluorescent Aptamers

引用

作者： Ioanna Théodorou Nam Nguyen Quang Karine Gombert Benoit Thézé Benoit Lelandais Frédéric Ducongé

Fluorescence imaging techniques could be used in different ways to study the interaction of aptamers with biological systems from cell culture to animal models. Here, we present the methods developed in our laboratory for fluorescently labeled aptamers, study their internalization inside living cells using time-lapse microscopy, and monitor their biodistribution in mice bearing subcutaneous xenograft tumors using planar fluorescence imaging and fluorescence diffuse optical tomography (fDOT). less

关键词： Time Lapse Microscopy Optical Tomography In Vivo Imaging Fluorescence Labeling Fluorescence Microscopy Cell And Tissue Culture Titration Spectroscopy Freeze-thaw Method Transillumination ImageJ Image Analysis Computed Tomography MRI Nucleic Acid Labeling Subcutaneous Injection 3D Imaging DNA hybridization programming language Rattus norvegicus Mus musculus MCF-7 Oligonucleotide Fluorescence Aptamer

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共114页 << < 59 60 61 62 63 64 65 66 67 68 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：