检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

500 篇 资讯
285 篇 期刊文献
235 篇 会议
67 册 图书
45 篇 学位论文

馆藏范围

1,132 篇 电子文献
1 种 纸本馆藏

日期分布

学科分类号

460 篇 工学
- 360 篇 计算机科学与技术...
- 192 篇 软件工程
- 117 篇 电气工程
- 52 篇 信息与通信工程
- 44 篇 控制科学与工程
- 13 篇 电子科学与技术（可...
- 11 篇 机械工程
- 8 篇 石油与天然气工程
- 6 篇 材料科学与工程（可...
- 5 篇 仪器科学与技术
- 4 篇 建筑学
- 4 篇 化学工程与技术
- 4 篇 网络空间安全
- 3 篇 力学（可授工学、理...
- 3 篇 动力工程及工程热...
- 3 篇 土木工程
- 3 篇 核科学与技术
- 3 篇 环境科学与工程（可...
59 篇 理学
- 22 篇 数学
- 17 篇 生物学
- 9 篇 物理学
- 5 篇 科学技术史(分学科...
- 4 篇 地球物理学
- 4 篇 系统科学
43 篇 教育学
- 40 篇 教育学
- 4 篇 心理学(可授教育学...
30 篇 管理学
- 24 篇 管理科学与工程(可...
- 5 篇 图书情报与档案管...
7 篇 农学
7 篇 医学
- 4 篇 基础医学(可授医学...
4 篇 法学
- 4 篇 社会学
3 篇 哲学
3 篇 经济学
3 篇 文学
2 篇 历史学

主题

1,132 篇 programming lang...
184 篇 python
180 篇 statistical calc...
168 篇 data analysis
78 篇 homo sapiens
72 篇 cell and tissue ...
68 篇 microarray
66 篇 machine learning
60 篇 pcr
58 篇 matlab
58 篇 rna-seq
58 篇 genomics
49 篇 image analysis
47 篇 programming
47 篇 mass spectrometr...
44 篇 principal compon...
43 篇 compiler
40 篇 proteomics
39 篇 genome visualiza...
39 篇 mus musculus

机构

16 篇 brno university ...
7 篇 charles universi...
6 篇 united states na...
3 篇 univ kebangsaan ...
2 篇 army engn univ p...
2 篇 hebei univ engn ...
2 篇 natl taipei univ...
2 篇 gannon univ dept...
2 篇 nanjing univ sta...
2 篇 college of compu...
2 篇 swiss fed inst t...
2 篇 texas a&m univer...
2 篇 data processing ...
2 篇 verivue
2 篇 univ new mexico ...
2 篇 aalto university
2 篇 politehn univ ti...
2 篇 institut für inf...
2 篇 univ glasgow gla...
2 篇 univ utah salt l...

作者

5 篇 rune matthiesen
4 篇 sharanya manohar...
4 篇 oviya ramalakshm...
4 篇 phillips andrew
3 篇 tshukudu ethel
3 篇 cedric gondro
3 篇 vijaykumar yoges...
3 篇 batmaz firat
3 篇 ana sofia carval...
3 篇 francesca grison...
3 篇 wu di
3 篇 junghyun namkung
3 篇 j. b. brown
3 篇 xu baowen
3 篇 chen lin
3 篇 roeland m. merks
3 篇 laercio r. porto...
3 篇 seung hwan lee
3 篇 christoph bock
3 篇 javier martínez-...

语言

1,089 篇 英文
35 篇 其他
6 篇 中文
1 篇 日文
1 篇 葡萄牙文

检索条件"主题词=Programming language"

共 1132 条记录，以下是791-800 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

ARIA for Solution and Solid-State NMR

ARIA for Solution and Solid-State NMR

引用

作者： Benjamin Bardiaux Thérèse Malliavin Michael Nilges

In solution or solid-state, determining the three-dimensional structure of biomolecules by Nuclear Magnetic Resonance (NMR) normally requires the collection of distance information. The interpretation of the spectra containing this distance information is a critical step in an NMR structure determination. In this chapter, we present the Ambiguous Restraints for Iterative Assignment (ARIA) program for automated cross-peak assignment and determination of macromolecular structure from solution and solid-state NMR experiments. While the program was initially designed for the assignment of nuclear Overhauser effect (NOE) resonances, it has been extended to the interpretation of magic-angle spinning (MAS) solid-state NMR data. This chapter first details the concepts and procedures carried out by the program. Then, we describe both the general strategy for structure determination with ARIA 2.3 and practical aspects of the technique. ARIA 2.3 includes all recent developments. such as an extended integration of the Collaborative Computing Project for the NMR community (CCPN), the incorporation of the log-harmonic distance restraint potential and an automated treatment of symmetric *** solution or solid-state, determining the three-dimensional structure of biomolecules by Nuclear Magnetic Resonance (NMR) normally requires the collection of distance information. The interpretation of the spectra containing this distance information is a critical step in an NMR structure determination. In this chapter, we present the Ambiguous Restraints for Iterative Assignment (ARIA) program for automated cross-peak assignment and determination of macromolecular structure from solution and solid-state NMR experiments. While the program was initially designed for the assignment of nuclear Overhauser effect (NOE) resonances, it has been extended to the interpretation of magic-angle spinning (MAS) solid-state NMR data. This chapter first details the concepts and procedures carried out

关键词： Solid-state NMR Structure Determination Magic Angle Spinning NMR Molecular Dynamics Simulation Simulated Annealing Python programming language NOE Automated assignment CCPN Structure calculation ARIA MAS Ambiguous distance restraint PDSD CHHC

来源：评论

学校读者我要写书评

暂无评论

Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy

Resolution doubling in live, multicellular organisms via mul...

引用

作者： Andrew G York Sapun H Parekh Damian Dalle Nogare Robert S Fischer Kelsey Temprine Marina Mione Ajay B Chitnis Christian A Combs Hari Shroff

We demonstrate three-dimensional (3D) super-resolution in live multicellular organisms using structured illumination microscopy (SIM). Sparse multifocal illumination patterns generated by a digital micromirror device (DMD) allowed us to physically reject out-of-focus light, enabling 3D subdiffractive imaging in samples eightfold thicker than had been previously imaged with SIM. We imaged samples at one 2D image per second, at resolutions as low as 145 nm laterally and 400 nm axially. In addition to dual-labeled, whole fixed cells, we imaged GFP-labeled microtubules in live transgenic zebrafish embryos at depths >45 μm. We captured dynamic changes in the zebrafish lateral line primordium and observed interactions between myosin IIA and F-actin in cells encapsulated in collagen gels, obtaining two-color 4D super-resolution data sets spanning tens of time points and minutes without apparent phototoxicity. Our method uses commercially available parts and open-source software and is simpler than existing SIM implementations, allowing easy integration with wide-field microscopes. less

关键词： Cellular Imaging Microscopy Structured Illumination Microscopy Chiral Separation Electroporation Live Cell Imaging ImageJ Python programming language

来源：评论

学校读者我要写书评

暂无评论

Analyzing Biological Data Using R: Methods for Graphs and Networks

Analyzing Biological Data Using R: Methods for Graphs and Ne...

引用

作者： Nolwenn Le Meur Robert Gentleman

R is a powerful language and widely used software tool for the analysis and visualization of data. Its core capabilities can be extended through many different add-on packages. Among the many packages are some which offer a broad range of facilities for analyzing statistical properties of graphs. This chapter provides a practical tutorial covering the use of R methods for graphs and networks to examine biological data and analyze their topological and statistical properties. less

关键词： Genotyping High-Throughput Sequencing Nucleic Acid Microarray Gene Expression Analysis DNA Sequencing programming language Microarray Escherichia coli Systems biology Network Graph Statistic Random graph

来源：评论

学校读者我要写书评

暂无评论

The Use of Open Source Bioinformatics Tools to Dissect Transcriptomic Data

The Use of Open Source Bioinformatics Tools to Dissect Trans...

引用

作者： Benjamin M. Nitsche Arthur F. Ram Vera Meyer

Microarrays are a valuable technology to study fungal physiology on a transcriptomic level. Various microarray platforms are available comprising both single and two channel arrays. Despite different technologies, preprocessing of microarray data generally includes quality control, background correction, normalization, and summarization of probe level data. Subsequently, depending on the experimental design, diverse statistical analysis can be performed, including the identification of differentially expressed genes and the construction of gene coexpression networks. We describe how Bioconductor, a collection of open source and open development packages for the statistical programming language R, can be used for dissecting microarray data. We provide fundamental details that facilitate the process of getting started with R and Bioconductor. Using two publicly available microarray datasets from Aspergillus niger, we give detailed protocols on how to identify differentially expressed genes and how to construct gene coexpression networks. less

关键词： Microarray Transcriptomics Gene Expression Profiling Statistical Calculation Principal Component Analysis Cytoscape programming language Data analysis Aspergillus niger Filamentous fungi Bioconductor Gene coexpression networks

来源：评论

学校读者我要写书评

暂无评论

Data Mining as a Discovery Tool for Imprinted Genes

Data Mining as a Discovery Tool for Imprinted Genes

引用

作者： Chelsea Brideau Paul Soloway

This chapter serves as an introduction to the collection of genome-wide sequence and epigenomic data, as well as the use of these data in training generalized linear models (glm) to predicted imprinted status. This is meant to be an introduction to the method, so only the most straightforward examples will be covered. For instance, the examples given below refer to 11 classes of genomic regions (the entire gene body, introns, exons, 5′ UTR, 3′ UTR, and 1, 10, and 100 kb upstream and downstream of each gene). One could also build models based on combinations of these regions. Likewise, models could be built on combinations of epigenetic features, or on combinations of both genomic regions and epigenetic features. This chapter relies heavily on computational methods, including basic programming. However, this chapter is not meant to be an introduction to programming. Throughout the chapter, the reader will be provided with example code in the Perl programming language. less

关键词： Data Mining Genome Visualization Gene Prediction Genome Assembly ChIP-seq Data analysis programming language Bioinformatics Epigenomics Epigenetics Imprinting Generalized linear model

来源：评论

学校读者我要写书评

暂无评论

Synthetic Networks: Oscillators and Toggle Switches for

Synthetic Networks: Oscillators and Toggle Switches for

引用

作者： Nicolas Perry Alexander J. Ninfa

Bacterial synthetic gene networks are constructed by manipulating the regulation of genes inside a cell, with the purpose of eliciting novel regulatory behaviors. The methods for manipulating genes and gene regulation in E. coli are well established, making it the preferred host for basic studies of synthetic networks. We focus our work on constructing two kinds of synthetic gene networks: toggle switches (bistable systems) and oscillators. Toggle switches are capable of exhibiting two stable steady states of gene expression (OFF and ON) without stable intermediate states; the steady state reached by the system depends on the previous history of the system. Biological oscillators exhibit regular cycles in gene expression around an unstable steady state. Studying these two kinds of synthetic networks helps advance our understanding of natural bistable systems and oscillators, such as the circadian oscillators controlling gene expression in many types of cells, and the genetic systems controlling the cell cycle and differentiation in metazoans. less

关键词： Restriction Enzyme Digestion Electroporation Colony PCR Microbial Culture PCR Gel Electrophoresis Transillumination Bacterial Transformation DNA Ligation programming language Escherichia coli Recombinant DNA Genetic circuit Genetic oscillator Genetic switch Genetic bistability Continuous culture automation

来源：评论

学校读者我要写书评

暂无评论

Analyzing Epigenome Data in Context of Genome Evolution and Human Diseases

Analyzing Epigenome Data in Context of Genome Evolution and ...

引用

作者： Lars Feuerbach Konstantin Halachev Yassen Assenov Fabian Müller Christoph Bock Thomas Lengauer

This chapter describes bioinformatic tools for analyzing epigenome differences between species and in diseased versus normal cells. We illustrate the interplay of several Web-based tools in a case study of CpG island evolution between human and mouse. Starting from a list of orthologous genes, we use the Galaxy Web service to obtain gene coordinates for both species. These data are further analyzed in EpiGRAPH, a Web-based tool that identifies statistically significant epigenetic differences between genome region sets. Finally, we outline how the use of the statistical programming language R enables deeper insights into the epigenetics of human diseases, which are difficult to obtain without writing custom scripts. In summary, our tutorial describes how Web-based tools provide an easy entry into epigenome data analysis while also highlighting the benefits of learning a scripting language in order to unlock the vast potential of public epigenome datasets. less

关键词： Genomics programming language Data analysis Homo sapiens Epigenomics DNA methylation Galaxy CpG islands Computational epigenetics EpiGRAPH

来源：评论

学校读者我要写书评

暂无评论

High-Throughput Phenotyping of Plant Populations Using a Personal Digital Assistant

High-Throughput Phenotyping of Plant Populations Using a Per...

引用

作者： Raju Naik Vankudavath Reddaiah Bodanapu Yellamaraju Sreelakshmi Rameshwar Sharma

During many biological experiments voluminous data is acquired, which can be best collected with portable data acquisition devices and later analyzed with a personal computer (PC). Public domain software catering to data acquisition and analysis is currently limited. The necessity of phenotyping large plant populations led to the development of the application “PHENOME” to manage the data. PHENOME allows acquisition of phenotypic data using a personal digital assistant (PDA) with a built-in barcode scanner. The acquired data can be exported to a customized database on a PC for further analysis and cataloging. PHENOME can be used for a variety of applications, for example high-throughput phenotyping of a mutagenized or mapping population, or phenotyping of several individuals in one or more ecological niches. less

关键词： Functional Genomics programming language High-throughput phenotyping Computable phenotypic database Computer-aided data acquisition Personal digital assistant

来源：评论

学校读者我要写书评

暂无评论

Single Marker Family-Based Association Analysis Not Conditional on Parental Information

Single Marker Family-Based Association Analysis Not Conditio...

引用

作者： Junghyun Namkung

Family-based association analysis unconditional on parental genotypes models the effects of observed genotypes. This approach has been shown to have greater power than conditional methods. In this chapter, I review two popular association analysis methods accounting for familial correlations: the marginal model using generalized estimating equations (GEE) and the mixed model with a polygenic random component. The marginal approach does not explicitly model familial correlations but uses the information to improve the efficiency of parameter estimates. This model, using GEE, is useful when the correlation structure is not of interest; the correlations are treated as nuisance parameters. In the mixed model, familial correlations are modeled as random effects, e.g., the polygenic inheritance model accounts for correlations originating from shared genomic components within a family. These unconditional methods provide a flexible modeling framework for general pedigree data to accommodate traits with various distributions and many types of covariate effects. The analysis procedures are demonstrated using the ASSOC program in the S.A.G.E. package and the R package gee, including how to prepare input data, conduct the analysis, and interpret the output. ASSOC allows models to include random components of additional familial correlations that may be not sufficiently explained by a polygenic effect and addresses nonnormality of response variables by transformation methods. With its ease of use, ASSOC provides a useful tool for association analysis of large pedigree data. less

关键词： Statistical Calculation programming language Heritability S.A.G.E. Family-based association test Unconditional method Observed genotype Polygenic inheritance Linear mixed model Marginal model Generalized estimating equations Generalized linear mixed model Variance components ASSOC R package gee Working correlation

来源：评论

学校读者我要写书评

暂无评论

Physiologically Based Pharmacokinetic/Toxicokinetic Modeling

Physiologically Based Pharmacokinetic/Toxicokinetic Modeling

引用

作者： Jerry L. Campbell Rebecca A. Clewell P. Robinan Gentry Melvin E. Andersen Harvey J. Clewell

Physiologically based pharmacokinetic (PBPK) models differ from conventional compartmental pharmacokinetic models in that they are based to a large extent on the actual physiology of the organism. The application of pharmacokinetics to toxicology or risk assessment requires that the toxic effects in a particular tissue are related in some way to the concentration time course of an active form of the substance in that tissue. The motivation for applying pharmacokinetics is the expectation that the observed effects of a chemical will be more simply and directly related to a measure of target tissue exposure than to a measure of administered dose. The goal of this work is to provide the reader with an understanding of PBPK modeling and its utility as well as the procedures used in the development and implementation of a model to chemical safety assessment using the styrene PBPK model as an example. less

关键词： Tube Feeding Monte Carlo Simulations MATLAB Statistical Calculation programming language Styrene Pharmacokinetics PBPK

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共114页 << < 76 77 78 79 80 81 82 83 84 85 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：