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检索条件"主题词=Txnip"
545 条 记 录,以下是31-40 订阅
排序:
LncRNA-SNHG3 promotes neuroinflammation post-intracerebral hemorrhage by regulating the miR-106b-5p/txnip axis
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MOLECULAR & CELLULAR TOXICOLOGY 2024年 第4期20卷 883-894页
作者: Zhou, Fenggang Wu, Fei Wang, Xinran Yu, Shihua Tian, Wenqi Lv, Ou Harbin Med Univ Dept Neurosurg Affiliated Hosp 2 246 Xuefu Rd Harbin 150086 Heilongjiang Peoples R China Harbin Med Univ Dept Neurol Affiliated Hosp 2 246 Xuefu Rd Harbin 150086 Heilongjiang Peoples R China
BackgroundIntracerebral hemorrhage (ICH) stands as the most fatal stroke subtype, lacking any specific therapeutic approach yielding benefits for functional *** aimed to explore the involvement of long non-coding RNA ... 详细信息
来源: 评论
Thioredoxin-interacting protein (txnip) inhibition promotes retinal ganglion cell survival and facilitates M1-like microglial transformation via the PI3K/Akt pathway in glaucoma
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MOLECULAR MEDICINE 2024年 第1期30卷 1-21页
作者: Chen, Junjue Zhong, Huimin Shen, Bingqiao Yu, Huan Zhang, Yang Han, Ruiqi Huang, Ping Huang, Shouyue Zhong, Yisheng Shanghai Jiao Tong Univ Ruijin Hosp Affiliated Dept Ophthalmol Med Sch 197 Ruijin Er Rd Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Shanghai Gen Hosp Shanghai Peoples Hosp 1 Dept OphthalmolSch Med Shanghai Peoples R China Shanghai Jiao Tong Univ Shanghai Key Lab Bone & Joint Dis Shanghai Inst Traumatol & Orthopaed Ruijin HospAffiliated Med Sch 197 Ruijin Er Rd Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Ruijin Hosp Affiliated Dept Ophthalmol Zhoushan BranchMed Sch Zhoushan Peoples R China
BackgroundGlaucoma is a group of heterogeneous neurodegenerative diseases with abnormal energy metabolism and imbalanced neuroinflammation in the retina. Thioredoxin-interacting protein (txnip) is involved in glucose ... 详细信息
来源: 评论
Targeting txnip in endothelial progenitors mitigates IL-8-induced neutrophil recruitment under metabolic stress
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STEM CELL RESEARCH & THERAPY 2024年 第1期15卷 225页
作者: Jolibois, Julia Domingues, Alison El Hamaoui, Divina Awaida, Raphael Berger-de-Gaillardo, Mathilde Guerin, Daniel Smadja, David M. Marquet-DeRouge, Perrine Margaill, Isabelle Rossi, Elisa Nivet-Antoine, Valerie Univ Paris Cite INSERM Innovat Therapeut Hemostase F-75006 Paris France Hop Necker Enfants Malad AP HP Lab Biochim Gen F-75015 Paris France Hop Europeen Georges Pompidou AP HP Lab Hematol F-75015 Paris France
BackgroundThis study explores the potential role of Thioredoxin-interacting protein (txnip) silencing in endothelial colony-forming cells (ECFCs) within the scope of age-related comorbidities and impaired vascular rep... 详细信息
来源: 评论
METTL3 Modulates txnip Expression to Affect the Activation of NLRP3 Inflammasome in Hepatic Cells Under Oxygen-Glucose Deprivation/Reperfusion Injury
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INFLAMMATION 2024年 第3期47卷 1028-1040页
作者: Zhang, Yong Lv, Jianrui Bai, Jian Zhang, Xue Wu, Gang Lei, Xiaoming Li, Wei Zhang, Zhenni Xi An Jiao Tong Univ Dept Gastroenterol Affiliated Hosp 2 157 Xiwu Rd Xian 710004 Shaanxi Peoples R China Capital Med Univ Xuanwu Hosp Dept Gen Surg Beijing Peoples R China Capital Med Univ Beijing Friendship Hosp Dept Gen Practice Beijing Peoples R China
Hepatic ischemia-reperfusion (I/R) injury is still a major risk factor and unsolved problem in hepatic surgery. Methyltransferase-like 3 (METTL3), an important m(6)A-modified methylase, regulates inflammation and cell... 详细信息
来源: 评论
Knockdown of txnip alleviates gestational diabetes mellitus by activating autophagy to regulate cell proliferation and apoptosis in high glucose-treated trophoblasts
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REPRODUCTIVE BIOLOGY 2024年 第1期24卷 100841-100841页
作者: Gu, Ying Cao, Minkai Chen, Yu Li, Jingyang Hu, Lingli Yang, Xiao-Jun Soochow Univ Affiliated Hosp 1 Dept Obstet & Gynecol Suzhou Peoples R China Jiangnan Univ Affiliated Womens Hosp Dept Obstet & Gynecol Wuxi Peoples R China Nanjing Med Univ Dept Obstet & Nanjing Nanjing Peoples R China Soochow Univ Affiliated Hosp 1 Dept Obstet & Gynecol Suzhou 215006 Jiangsu Peoples R China
Dysregulated thioredoxin-interacting protein (txnip) has been observed in women with gestational diabetes mellitus (GDM), but the specific role of txnip in GDM and the underlying mechanism remain unclear. HTR-8/ SVneo... 详细信息
来源: 评论
Increased level of txnip and nuclear translocation of TXN is associated with end stage renal disease and development of multiplex renal tumours
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BMC NEPHROLOGY 2024年 第1期25卷 1页
作者: Beothe, Tamas Docs, Janos Kovacs, Gyula Peterfi, Lehel Peterfy Sandor Hosp Dept Urol Budapest Hungary Univ Pecs Med Sch Dept Urol Munkacsy Mihaly u 2 H-7621 Pecs Hungary Ruprecht Karls Univ Heidelberg Med Fac Heidelberg Germany
BackgroundEnd-stage and acquired cystic renal disease (ESRD/ACRD) kidneys are characterized by inflammatory remodelling and multiplex renal cell carcinomas (RCC). Eosinophilic vacuolated tumour (EVT) occurs exclusivel... 详细信息
来源: 评论
Astragaloside IV attenuates podocyte apoptosis via regulating txnip/NLRP3/GSDMD signaling pathway in diabetic nephropathy
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DIABETOLOGY & METABOLIC SYNDROME 2024年 第1期16卷 1-16页
作者: Hu, Zhibo Zhou, Yu Gao, Cailing Liu, Junfen Pan, Congqing Guo, Jun Tianjin Med Univ Chu Hsien Mem Hosp 1 Tianjin Key Lab Metab Dis NHC Key Lab Hormones & Dev Tianjin 300134 Peoples R China Tianjin Med Univ Tianjin Inst Endocrinol Tianjin 300134 Peoples R China
ObjectivesAmong all the diabetes complications brought on by persistent inflammation is diabetic kidney disease (DKD). One essential method of the inflammatory response's programmed cell death is anthrax. One of t... 详细信息
来源: 评论
METTL3-mediated m6A modification of pri-miR-148a-3p affects prostate cancer progression by regulating txnip
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ENVIRONMENTAL TOXICOLOGY 2023年 第10期38卷 2377-2390页
作者: Li, Guoqiang Liu, Junwen Wang, Yinhuai Liu, Hanqi Fu, Jianhan Zhao, Yuanqiao Huang, Yanqing Cent South Univ Xiangya Hosp 2 Dept Urol Changsha Peoples R China Cent South Univ Xiangya Sch Med Dept Histol & Embryol 172 Tongzipo Rd Changsha 410000 Peoples R China
ObjectiveProstate cancer (PCa) severely affects men's health worldwide. The mechanism of methyltransferase-like 3 (METTL3) in affecting PCa development by regulating miR-148a-3p expression via N6-methyladenosine (... 详细信息
来源: 评论
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-txnip-NLRP3 Axis and Pyroptosis
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023年 第3期71卷 1499-1509页
作者: Tian, Yicheng Feng, Xinyuan Zhou, Zimo Qin, Sen Chen, Senxiang Zhao, Jihui Hou, Jianglin Liu, Da China Med Univ Dept Orthoped Shengjing Hosp Shenyang 110004 Liaoning Peoples R China
Osteoarthritis (OA) is a common joint disease, and studies have reported that the endoplasmic reticulum stress (ERS) in chondrocytes caused by the cartilage tissue damage could mediate the activation of Nod-like recep... 详细信息
来源: 评论
Epigallocatechin-3-Gallate Ameliorates Diabetic Kidney Disease by Inhibiting the txnip/NLRP3/IL-1β Signaling Pathway
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FOOD SCIENCE & NUTRITION 2024年 第12期12卷 10800-10815页
作者: Wang, Yinghui Wang, Qimeng Wang, Mingming Wang, Xueling Liu, Qingzhen Lv, Shasha Nie, Huibin Liu, Gang Shandong Univ Multidisciplinary Innovat Ctr Nephrol Dept Nephrol Hosp 2 Jinan Shandong Peoples R China Shandong Univ Nephrol Res Inst Jinan Shandong Peoples R China Chengdu Univ TCM Chengdu Peoples Hosp 1 Dept Nephrol Integrated TCM & Western Med Hosp Chengdu Sichuan Peoples R China Shandong Univ Key Lab Reprod Endocrinol Minist Educ Jinan Shandong Peoples R China
Recent research indicates that the activation of the NLRP3 inflammasome is crucial in the development of diabetic kidney disease (DKD). Epigallocatechin-3-gallate (EGCG), the predominant catechin in green tea, has bee... 详细信息
来源: 评论