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检索条件"主题词=Txnip"
545 条 记 录,以下是61-70 订阅
排序:
YAP/miR-524-5p axis negatively regulates txnip expression to promote chondrosarcoma cell growth
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2022年 590卷 20-26页
作者: Liu, Ri-Xu Tang, Wang Zheng, Bo-Yuan Yang, Yong Li, Zhen-Yan Gui, Tao Zhang, Huan-Tian Liu, Ning Zha, Zhen-Gang Li, Jing-Xiang Jinan Univ Affiliated Hosp 1 Ctr Joint Surg & Sports Med Guangzhou 510630 Peoples R China Jinan Univ Inst Orthoped Dis & Bone Guangzhou 510630 Peoples R China Jinan Univ Joint Dis Inst Guangdong Hong Kong Macao Greater Guangzhou 510630 Peoples R China Jinan Univ Dept Joint Surg Affiliated Shunde Hosp Foshan 528305 Peoples R China Southern Med Univ NanFang Hosp Guangzhou 510515 Peoples R China
Chondrosarcoma (CHS) is the second most common bone malignant tumor and currently has limited treatment options. We have recently demonstrated that thioredoxin interacting protein (txnip) plays a crucial role in the o... 详细信息
来源: 评论
Melatonin alleviates lead-induced intestinal epithelial cell pyroptosis in the common carps (Cyprinus carpio) via miR-17-5p/txnip axis
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FISH & SHELLFISH IMMUNOLOGY 2022年 131卷 127-136页
作者: Miao, Zhiying Miao, Zhiruo Teng, Xiaohua Xu, Shiwen Northeast Agr Univ Coll Life Sci Harbin 150030 Peoples R China Northeast Agr Univ Coll Anim Sci & Technol Harbin 150030 Peoples R China Northeast Agr Univ Coll Vet Med Harbin 150030 Peoples R China Northeast Agr Univ Coll Vet Med Key Lab Prov Educ Dept Heilongjiang Common Anim D Harbin 150030 Peoples R China
Lead (Pb) has been concerned as one of the most severe hazardous contaminants, because it can cause pyroptosis in multiple tissues of mammals and birds. Melatonin (Mel) has attracted much interest for its role in gove... 详细信息
来源: 评论
Salidroside Alleviates Chronic Constriction Injury-Induced Neuropathic Pain and Inhibits of txnip/NLRP3 Pathway
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NEUROCHEMICAL RESEARCH 2022年 第2期47卷 493-502页
作者: Hu, Tingting Sun, Qingyu Gou, Yu Zhang, Yurui Ding, Yumeng Ma, Yiran Liu, Jing Chen, Wen Lan, Ting Wang, Peipei Li, Qian Yang, Fei Capital Med Univ Dept Neurobiol Sch Basic Med Sci Adv Innovat Ctr Human Brain ProtectBeijing Key L 10 You An Men Wai Xi Tou Tiao Beijing 100069 Peoples R China Capital Med Univ Beijing Key Lab Neural Regenerat & Repair Adv Innovat Ctr Human Brain Protect Dept Biochem & Mol BiolSch Basic Med Sci Beijing Peoples R China Tianjin Univ Tianjin Hosp Dept Orthopaed Surg Tianjin Peoples R China
Neuropathic pain is one of the most common conditions requiring treatment worldwide. Salidroside (SAL), a phenylpropanoid glucoside extracted from Rhodiola, has been suggested to produce an analgesic effect in chronic... 详细信息
来源: 评论
Ceramide induces pyroptosis through txnip/NLRP3/GSDMD pathway in HUVECs
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BMC MOLECULAR AND CELL BIOLOGY 2022年 第1期23卷 54页
作者: Liu, Fangfang Zhang, Yangyang Shi, Yining Xiong, Kai Wang, Fugui Yang, Jin Anhui Med Univ Affiliated Hosp 2 Dept Resp & Crit Care Med Hefei 230601 Anhui Peoples R China Chest Hosp Anhui Prov Dept Resp & Crit Care Med Hefei Anhui Peoples R China Anhui Med Univ Affiliated Hosp 2 Dept Emergency Med Hefei Anhui Peoples R China Anhui Med Univ Affiliated Hosp 2 Inst Resp Dis Hefei 230601 Anhui Peoples R China
Background: Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeabili... 详细信息
来源: 评论
miR-223 Enhances the Neuroprotection of Estradiol Against Oxidative Stress Injury by Inhibiting the FOXO3/txnip Axis
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NEUROCHEMICAL RESEARCH 2022年 第7期47卷 1865-1877页
作者: Pan, Qiong Ma, Jiezhi Guo, Ke Cent South Univ Dept Obstet & Gynecol Xiangya Hosp 3 Changsha 410013 Peoples R China Cent South Univ Dept Neurol Xiangya Hosp 3 Changsha 410013 Peoples R China
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder characterized by complex pathogenesis, of which oxidative stress has long been regarded as a major mechanism. Previously, the protective effec... 详细信息
来源: 评论
Antidiabetic effects of quercetin and liraglutide combination through modulation of txnip/IRS-1/PI3K pathway
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CELL BIOCHEMISTRY AND FUNCTION 2022年 第1期40卷 90-102页
作者: Eraky, Salma M. Ramadan, Nehal M. El-Magd, Nada F. Abo Mansoura Univ Fac Pharm Dept Biochem Mansoura 35516 Egypt Mansoura Univ Fac Med Clin Pharmacol Dept Mansoura Egypt
The study was designed to assess the possible augmented antidiabetic effects of combining quercetin and liraglutide in a type 1 diabetes model, with emphasis on the contribution of hepatic thioredoxin interacting prot... 详细信息
来源: 评论
Exosomal miR-17-5p from adipose-derived mesenchymal stem cells inhibits abdominal aortic aneurysm by suppressing txnip-NLRP3 inflammasome
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STEM CELL RESEARCH & THERAPY 2022年 第1期13卷 349页
作者: Hu, Jiateng Jiang, Yihong Wu, Xiaoyu Wu, Zhaoyu Qin, Jinbao Zhao, Zhen Li, Bo Xu, Zhijue Lu, Xinwu Wang, Xin Liu, Xiaobing Shanghai Jiao Tong Univ Shanghai Peoples Hosp 9 Dept Vasc Surg Sch Med Shanghai Peoples R China Shanghai Jiao Tong Univ Vasc Ctr Shanghai Peoples R China
Background Preclinical studies have suggested that adipose-derived mesenchymal stem cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm expansion through paracrine factors. Yet, the m... 详细信息
来源: 评论
ITCH facilitates proteasomal degradation of txnip in hypoxia- induced lung cancer cells
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THORACIC CANCER 2022年 第15期13卷 2235-2247页
作者: Sun, Qian Wang, Bi-Bo Wei, Wei Huang, Gui-Chun Liu, Lei-Lei Chen, Wei-Wei Wang, Jing Zhao, Xiao-Yue Lu, Lu Fang, Rong Zhu, Chun-Yan Chu, Xiao-Yuan Jinling Hosp Dept Med Oncol 305 Zhongshan East Rd Nanjing 210000 Peoples R China Jinling Hosp Dept Cardiothorac Surg Nanjing Peoples R China Nanjing Univ Jinling Hosp Med Sch Dept Med Oncol Nanjing Peoples R China Jinling Hosp Dept Pathol Nanjing Peoples R China
Background Lung cancer (LC) is one of the most common cancers and a leading cause of cancer-related deaths worldwide. In many pathological conditions, particularly in the tumor microenvironment, cells and tissues freq... 详细信息
来源: 评论
Acupuncture at ST36 Alleviates the Behavioral Disorder of Autistic Rats by Inhibiting txnip-Mediated Activation of NLRP3
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 2022年 第2期81卷 127-134页
作者: Zhao, Pengju Fu, Hongguang Cheng, Hui Zheng, Ruijuan Yuan, Dan Yang, Jianquan Li, Sheng Li, Enyao Li, Liguo Zhengzhou Univ Dept Children Rehabil Key Lab Rehabil Med Henan Affiliated Hosp 5 3 Rehabil St Zhengzhou 450052 Peoples R China Zhengzhou Hlth Vocat Coll Inst Hlth Engn Zhengzhou Peoples R China Sichuan Univ Coll Life Sci Chengdu Peoples R China
Autism is a common neurodevelopmental disorder that severely affects patients' quality of life. We aimed to investigate whether acupuncture at Zusanli (ST36) could alleviate the behavior disorder of autistic rats ... 详细信息
来源: 评论
txnip promotes autophagic apoptosis in diabetic cardiomyopathy by upregulating FoxO1 and its acetylation
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CELLULAR SIGNALLING 2024年 124卷 111469页
作者: Zhang, Yaoting Li, Bing Fu, Yu Cai, He Zheng, Yang First Hosp Jilin Univ Dept Cardiovasc Dis Changchun 130021 Peoples R China
Autophagy dysfunction and apoptosis exacerbate the risk of heart failure in patients with diabetic cardiomyopathy (DCM). However, the interactions between autophagy and apoptosis in DCM and their underlying mechanisms... 详细信息
来源: 评论