检索结果-内蒙古大学图书馆

BioDSNN: a dual-stream neural network with hybrid biological knowledge integration for multi-gene perturbation response prediction

引用

BRIEFINGS IN BIOINFORMATICS 2024年第1期26卷 bbae617页

作者： Tan, Yuejun Xie, Linhai Yang, Hong Zhang, Qingyuan Luo, Jinyuan Zhang, Yanchun Guangzhou Univ Cyberspace Inst Adv Technol Guangzhou 510000 Peoples R China Zhejiang Normal Univ Sch Comp Sci & Technol Jinhua 321000 Peoples R China Natl Ctr Prot Sci Beijing State Key Lab Prote Beijing 100000 Peoples R China Int Acad Phronesis Med Guangzhou 510000 Peoples R China

Studying the outcomes of genetic perturbation based on single-cell RNA-seq data is crucial for understanding genetic regulation of cells. However, the high cost of cellular experiments and single-cell sequencing restrict us from measuring the full combination space of genetic perturbations and cell types. Consequently, a bunch of computational models have been proposed to predict unseen combinations based on existing data. Among them, generative models, e.g. variational autoencoder and diffusion models, have the superiority in capturing the perturbed data distribution, but lack a biologically understandable foundation for generalization. On the other side of the spectrum, Gene Regulation Networks or gene pathway knowledge have been exploited for more reasonable generalization enhancement. Unfortunately, they do not reach a balanced processing of the two data modalities, leading to a degraded fitting ability. Hence, we propose a dual-stream architecture. Before the information from two modalities are merged, the sequencing data are learned with a generative model while three types of knowledge data are comprehensively processed with graph networks and a masked transformer, enforcing a deep understanding of single-modality data, respectively. The benchmark results show an approximate 20% reduction in terms of mean squared error, proving the effectiveness of the model.

关键词： genetic perturbation predict biological knowledge masked attention variational autoencoder

来源：评论

学校读者我要写书评

暂无评论

Active Patterns Perceived for Stochastic Video Prediction 22

Active Patterns Perceived for Stochastic Video Prediction

引用

30th ACM International Conference on Multimedia (MM)

作者： Xu, Yechao Sun, Zhengxing Li, Qian Sun, Yunhan Luo, Shoutong Nanjing Univ State Key Lab Novel Software Technol Nanjing Jiangsu Peoples R China Natl Univ Def Technol Coll Meteorol & Oceanog Changsha Hunan Peoples R China

ISBN: (纸本)9781450392037

Predicting future scenes based on historical frames is challenging, especially when it comes to the complex uncertainty in nature. We observe that there is a divergence between spatial-temporal variations of active patterns and non-active patterns in a video, where these patterns constitute visual content and the former ones implicate more violent movement. This divergence enables active patterns the higher potential to act with more severe future uncertainty. Meanwhile, the existence of non-active patterns provides an opportunity for machines to examine some underlying rules with a mutual constraint between non-active patterns and active patterns. In order to solve this divergence, we provide a method called active patterns-perceived stochastic video prediction (ASVP) which allows active patterns to be perceived by neural networks during training. Our method starts with separating active patterns along with non-active ones from a video. Then, both scene-based prediction and active pattern-perceived prediction are conducted to respectively capture the variations within the whole scene and active patterns. Specially for active pattern-perceived prediction, a conditional generative adversarial network (CGAN) is exploited to model active patterns as conditions, with a variational autoencoder (VAE) for predicting the complex dynamics of active patterns. Additionally, a mutual constraint is designed to improve the learning procedure for the network to better understand underlying interacting rules among these patterns. Extensive experiments are conducted on both KTH human action and BAIR action-free robot pushing datasets with comparison to state-of-the-art works. Experimental results demonstrate the competitive performance of the proposed method as we expected. The released code and models are at https://***/tolearnmuch/ASVP.

关键词： Video prediction Stochastic video prediction Conditional generative adversarial network variational autoencoder Active pattern mining

来源：评论

学校读者我要写书评

暂无评论

Rate Controllable Learned Image Compression Based on RFL Model

Rate Controllable Learned Image Compression Based on RFL Mod...

引用

IEEE International Conference on Visual Communications and Image Processing (VCIP)

作者： Zhang, Saiping Wang, Luge Mao, Xionghui Yang, Fuzheng Wan, Shuai Xidian Univ Sch Telecommun Engn Xian Peoples R China Northwestern Polytech Univ Sch Elect & Informat Xian Peoples R China

ISBN: (纸本)9781665475921

In this paper, we propose a rate controllable image compression framework, Rate Controllable variational autoencoder (RC-VAE), based on the Rate-Feature-Level (RFL) model established through our exploration on the correlation among target rates, image features and quantization levels. Considering that, when meeting the same target rate, different images should be quantized in different levels, we focus on jointly utilizing the target rate and the extracted features of the image to predict the corresponding quantization level and propose the RFL model. Combining the proposed RFL model with a Hyperprior Continuously Variable Rate (HCVR) image compression network, we further propose the RC-VAE. By controlling information loss in quantization process, the RC-VAE can work at the target rate. Experimental results have demonstrated that one single RC-VAE model can adapt to multiple target rates with higher rate control accuracy and better R-D performance compared with the stateof-the-art rate controllable image compression networks.

关键词： Deep image compression rate control variational autoencoder rate-distortion

来源：评论

学校读者我要写书评

暂无评论

Multi-Agent Reinforcement Learning with Clustering and Experience Sharing

引用

Procedia Computer Science 2024年 246卷 1329-1337页

作者： Kaname Inokuchi Toshiharu Sugawara Department of Computer Science and Communications Engineering Waseda University Japan

We propose a training method for a heterogeneous multi-agent system to improve the learning efficiency in sparse-reward environments. Although extensive research on multi-agent deep reinforcement learning are conducted actively, these studies often assume that all agents are homogeneous to share/utilize learning parameters in their networks. Unfortunately, this is not always the case in real-world applications where heterogeneous autonomous agents, i.e., those with different capabilities and perspectives, must properly cooperate and coordinate with each other. In our learning method, which is an extension of the shared experience actor-critic (SEAC) for a heterogeneous agent environment, agents are classified depending on their features (such as trajectories of the observations, actions and received rewards) using variational autoencoder, and share their experience among agents within each cluster to train their individual agents for improving the learning efficiency in a sparse-reward environment. Our experimental evaluation shows that the proposed method is capable of more efficient cooperative/coordinated behaviors than the baselines while remaining the advantages of SEAC.

关键词： Multi-agent deep reinforcement learning Experience Sharing variational autoencoder heterogeneous multi-agent systems Sparse-reward environment

来源：评论

学校读者我要写书评

暂无评论

Disentangling Rotational Dynamics and Ordering Transitions in a System of Self-Organizing Protein Nanorods via Rotationally Invariant Latent Representations

引用

ACS NANO 2021年第4期15卷 6471-6480页

作者： Kalinin, Sergei, V Zhang, Shuai Valleti, Mani Pyles, Harley Baker, David De Yoreo, James J. Ziatdinov, Maxim Univ Washington Mat Sci & Engn Seattle WA 98195 USA Pacific Northwest Natl Lab Phys Sci Div Richland WA 99354 USA Univ Tennessee Bredesen Ctr Interdisciplinary Res Knoxville TN 37996 USA Univ Washington Dept Biochem Seattle WA 98195 USA Univ Washington Inst Prot Design Seattle WA 98195 USA Univ Washington Inst Prot Design Dept Biochem Seattle WA 98195 USA Univ Washington Howard Hughes Med Inst Seattle WA 98195 USA Oak Ridge Natl Lab Ctr Nanophase Mat Sci Oak Ridge TN 37831 USA Oak Ridge Natl Lab Computat Sci & Engn Div Oak Ridge TN 37831 USA

The dynamics of complex ordering systems with active rotational degrees of freedom exemplified by protein self-assembly is explored using a machine learning workflow that combines deep learning-based semantic segmentation and rotationally invariant variational autoencoder-based analysis of orientation and shape evolution. The latter allows for disentanglement of the particle orientation from other degrees of freedom and compensates for lateral shifts. The disentangled representations in the latent space encode the rich spectrum of local transitions that can now be visualized and explored via continuous variables. The time dependence of ensemble averages allows insight into the time dynamics of the system and, in particular, illustrates the presence of the potential ordering transition. Finally, analysis of the latent variables along the single-particle trajectory allows tracing these parameters on a single-particle level. The proposed approach is expected to be universally applicable for the description of the imaging data in optical, scanning probe, and electron microscopy seeking to understand the dynamics of complex systems where rotations are a significant part of the process.

关键词： self-assembly latent space models deep learning variational autoencoder representation learning

来源：评论

学校读者我要写书评

暂无评论

Unsupervised Deep Anomaly Detection in Chest Radiographs

引用

JOURNAL OF DIGITAL IMAGING 2021年第2期34卷 418-427页

作者： Nakao, Takahiro Hanaoka, Shouhei Nomura, Yukihiro Murata, Masaki Takenaga, Tomomi Miki, Soichiro Watadani, Takeyuki Yoshikawa, Takeharu Hayashi, Naoto Abe, Osamu Univ Tokyo Hosp Dept Computat Diagnost Radiol & Prevent Med Bunkyo Ku 7-3-1 Hongo Tokyo Japan Univ Tokyo Hosp Dept Radiol Bunkyo Ku 7-3-1 Hongo Tokyo Japan Japan Univ Econ Dept Management 3-11-25 Gojo Dazaifu Fukuoka Japan Univ Tokyo Grad Sch Med Div Radiol & Biomed Engn Bunkyo Ku 7-3-1 Hongo Tokyo Japan

The purposes of this study are to propose an unsupervised anomaly detection method based on a deep neural network (DNN) model, which requires only normal images for training, and to evaluate its performance with a large chest radiograph dataset. We used the auto-encoding generative adversarial network (alpha-GAN) framework, which is a combination of a GAN and a variational autoencoder, as a DNN model. A total of 29,684 frontal chest radiographs from the Radiological Society of North America Pneumonia Detection Challenge dataset were used for this study (16,880 male and 12,804 female patients;average age, 47.0 years). All these images were labeled as "Normal," "No Opacity/Not Normal," or "Opacity" by board-certified radiologists. About 70% (6,853/9,790) of the Normal images were randomly sampled as the training dataset, and the rest were randomly split into the validation and test datasets in a ratio of 1:2 (7,610 and 15,221). Our anomaly detection system could correctly visualize various lesions including a lung mass, cardiomegaly, pleural effusion, bilateral hilar lymphadenopathy, and even dextrocardia. Our system detected the abnormal images with an area under the receiver operating characteristic curve (AUROC) of 0.752. The AUROCs for the abnormal labels Opacity and No Opacity/Not Normal were 0.838 and 0.704, respectively. Our DNN-based unsupervised anomaly detection method could successfully detect various diseases or anomalies in chest radiographs by training with only the normal images.

关键词： Chest radiograph variational autoencoder Generative adversarial network Deep learning Unsupervised learning Anomaly detection

来源：评论

学校读者我要写书评

暂无评论

The application of artificial intelligence-assisted technology in cultural and creative product design

引用

SCIENTIFIC REPORTS 2024年第1期14卷 1-18页

作者： Liang, Jing Jiangxi Inst Fash Technol Sch Fash Media Nanchang 330000 Peoples R China

This study proposes a novel artificial intelligence (AI)-assisted design model that combines variational autoencoders (VAE) with reinforcement learning (RL) to enhance innovation and efficiency in cultural and creative product design. By introducing AI-driven decision support, the model streamlines the design workflow and significantly improves design quality. The study establishes a comprehensive framework and applies the model to four distinct design tasks, with extensive experiments validating its performance. Key factors, including creativity, cultural adaptability, and practical application, are evaluated through structured surveys and expert feedback. The results reveal that the VAE + RL model surpasses alternative approaches across multiple criteria. Highlights include a user satisfaction rate of 95%, a Structural Similarity Index (SSIM) score of 0.92, model accuracy of 93%, and a loss reduction to 0.07. These findings confirm the model's superiority in generating high-quality designs and achieving high user satisfaction. Additionally, the model exhibits strong generalization capabilities and operational efficiency, offering valuable insights and data support for future advancements in cultural product design technology.

关键词： Artificial intelligence Cultural and creative product design variational autoencoder Reinforcement learning Design optimization

来源：评论

学校读者我要写书评

暂无评论

Data-driven fault detection for chemical processes using autoencoder with data augmentation

引用

KOREAN JOURNAL OF CHEMICAL ENGINEERING 2021年第12期38卷 2406-2422页

作者： Lee, Hodong Kim, Changsoo Jeong, Dong Hwi Lee, Jong Min Seoul Natl Univ Sch Chem & Biol Engn Inst Chem Proc 1 Gwanak Ro Seoul 08826 South Korea Korea Inst Sci & Technol Clean Energy Res Ctr Seoul 02792 South Korea Univ Ulsan Sch Chem Engn 93 Daehak Ro Ulsan 44610 South Korea

Process monitoring plays an essential role in safe and profitable operations. Various data-driven fault detection models have been suggested, but they cannot perform properly when the training data are insufficient or the information to construct the manifold is confined to a specific region. In this study, a process monitoring framework integrated with data augmentation is proposed to supplement rare but informative samples for the boundary regions of the normal state. To generate data for augmentation, a variational autoencoder was employed to exploit its advantage of stable convergence. For the construction of the process monitoring system, an autoencoder that can extract useful features in an unsupervised manner was used. To illustrate the efficacy of the proposed method, a case study for the Tennessee Eastman process was applied. The results show that the proposed method can improve the monitoring performance compared to the autoencoder without data augmentation in terms of fault detection accuracy and delay, particularly within the feature space.

关键词： Process Monitoring Fault Detection and Isolation (FDI) autoencoder variational autoencoder Data Augmentation

来源：评论

学校读者我要写书评

暂无评论

Energy Theft Detection Model Based on VAE-GAN for Imbalanced Dataset

引用

ENERGIES 2023年第3期16卷 1109-1109页

作者： Sun, Youngghyu Lee, Jiyoung Kim, Soohyun Seon, Joonho Lee, Seongwoo Kyeong, Chanuk Kim, Jinyoung Kwangwoon Univ Dept Elect Convergence Engn Seoul 01897 South Korea

Energy theft causes a lot of economic losses every year. In the practical environment of energy theft detection, it is required to solve imbalanced data problem where normal user data are significantly larger than energy theft data. In this paper, a variational autoencoder-generative adversarial network (VAE-GAN)-based energy theft-detection model is proposed to overcome the imbalanced data problem. In the proposed model, the VAE-GAN generates synthetic energy theft data with the features of real energy theft data for augmenting the energy theft dataset. The obtained balanced dataset is applied to train a detector which is designed as one-dimensional convolutional neural network. The proposed model is simulated on the practical dataset for comparing with various generative models to evaluate their performance. From simulation results, it is confirmed that the proposed model outperforms the other existing models. Additionally, it is shown that the proposed model is also very useful in the environments of extreme data imbalance for a wide variety of applications by analyzing the performance of detector according to the balance rate.

关键词： energy theft imbalanced dataset data augmentation variational autoencoder generative adversarial network

来源：评论

学校读者我要写书评

暂无评论

Latent Out: an unsupervised deep anomaly detection approach exploiting latent space distribution

引用

MACHINE LEARNING 2023年第11期112卷 4323-4349页

作者： Angiulli, Fabrizio Fassetti, Fabio Ferragina, Luca Univ Calabria DIMES I-87036 Arcavacata Di Rende Italy

Anomaly detection methods exploiting autoencoders (AE) have shown good performances. Unfortunately, deep non-linear architectures are able to perform high dimensionality reduction while keeping reconstruction error low, thus worsening outlier detecting performances of AEs. To alleviate the above problem, recently some authors have proposed to exploit variational autoencoders (VAE) and bidirectional Generative Adversarial Networks (GAN), which arise as a variant of standard AEs designed for generative purposes, both enforcing the organization of the latent space guaranteeing continuity. However, these architectures share with standard AEs the problem that they generalize so well that they can also well reconstruct anomalies. In this work we argue that the approach of selecting the worst reconstructed examples as anomalies is too simplistic if a continuous latent space autoencoder-based architecture is employed. We show that outliers tend to lie in the sparsest regions of the combined latent/error space and propose the VAEOut and LatentOut unsupervised anomaly detection algorithms, identifying outliers by performing density estimation in this augmented feature space. The proposed approach shows sensible improvements in terms of detection performances over the standard approach based on the reconstruction error.

关键词： Anomaly detection variational autoencoder Nearest neighbor density estimation

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：