检索结果-内蒙古大学图书馆

Surface-Engineered Nanomaterials for Optical array based sensing

CHEMPLUSCHEM 2024年第5期89卷 e202300610页

作者： Behera, Pradipta De, Mrinmoy Indian Inst Sci Dept Organ Chem Bangalore 560012 India

array based sensing governed by optical methods provides fast and economic way for detection of wide variety of analytes where the ideality of detection processes depends on the sensor element's versatile mode of interaction with multiple analytes in an unbiased manner. This can be achieved by either the receptor unit having multiple recognition moiety, or their surface property should possess tuning ability upon fabrication called surface engineering. Nanomaterials have a high surface to volume ratio, making them viable candidates for molecule recognition through surface adsorption phenomena, which makes it ideal to meet the above requirements. Most crucially, by engineering a nanomaterial's surface, one may produce cross-reactive responses for a variety of analytes while focusing solely on a single nanomaterial. Depending on the nature of receptor elements, in the last decade the array-based sensing has been considering as multimodal detection platform which operates through various pathway including single channel, multichannel, binding and indicator displacement assay, sequential ON-OFF sensing, enzyme amplified and nanozyme based sensing etc. In this review we will deliver the working principle for array-based sensing by using various nanomaterials like nanoparticles, nanosheets, nanodots and self-assembled nanomaterials and their surface functionality for suitable molecular recognition. Nanomaterials can be fabricated as receptors for various analytes upon surface functionalization. This property makes them ideal candidate for hypothesis free sensing applications. Different surface engineered nanomaterials and their implementation in the sensor array for recognition of wide range of analytes are summarized in this ***

关键词： array-based sensing colorimetric sensors fluorescence sensors nanomaterials surface modification

来源：评论

学校读者我要写书评

暂无评论

Machine Learning-Assisted array-based Biomolecular sensing Using Surface-Functionalized Carbon Dots

引用

ACS SENSORS 2019年第10期4卷 2730-2737页

作者： Pandit, Subhendu Banerjee, Tuseeta Srivastava, Indrajit Nie, Shuming Pan, Dipanjan Univ Illinois Dept Chem Urbana IL 61801 USA Univ Illinois Dept Bioengn Urbana IL 61801 USA Univ Illinois Dept Mat Sci & Engn Urbana IL 61801 USA Wolfram Res Inc Champaign IL 61801 USA Mills Breast Canc Res Inst Biomed Res Ctr Urbana IL 61801 USA Carle Fdn Hosp Urbana IL 61801 USA Univ Maryland Dept Radiol 670 Baltimore St Baltimore MD 21201 USA Univ Maryland Baltimore Cty Dept Chem Biochem & Environm Engn Hlth Sci Facil 3 670 Baltimore St Baltimore MD 21201 USA

Fluorescent array-based sensing is an emerging differential sensing platform for sensitive detection of analytes in a complex environment without involving a conventional "lock and key" type-specific interaction. These sensing techniques mainly rely on different optical pattern generation from a sensor array and their pattern recognition to differentiate analytes. Currently emerging, compelling pattern-recognition method, Machine Learning (ML), enables a machine to "learn" a pattern by training without having the recognition method explicitly programmed into it. Thus, ML has an enormous potential to analyze these sensing data better than widely used statistical pattern-recognition methods. Here, an array-based sensor using easy-to-synthesize carbon dots with varied surface functionality is reported, which can differentiate between eight different proteins at 100 nM concentration. The utility of using machine learning algorithms in pattern recognition of fluorescence signals from the array has also been demonstrated. In analyzing the array-based sensing data, Machine Learning algorithms like "Gradient-Boosted Trees" have achieved a 100% prediction efficiency compared to inferior-performing classical statistical method "Linear Discriminant Analysis".

关键词： array-based sensing machine learning chemical nose carbon dots surface chemistry

来源：评论

学校读者我要写书评

暂无评论

array-based sensing using nanoparticles: an alternative approach for cancer diagnostics

引用

NANOMEDICINE 2014年第10期9卷 1487-1498页

作者： Le, Ngoc D. B. Yazdani, Mahdieh Rotello, Vincent M. Univ Massachusetts Dept Chem Amherst MA 01003 USA

array-based sensing using nanoparticles (NPs) provides an attractive alternative to specific biomarker-focused strategies for cancer diagnosis. The physical and chemical properties of NPs provide both the recognition and transduction capabilities required for biosensing. array-based sensors utilize a combined response from the interactions between sensors and analytes to generate a distinct pattern (fingerprint) for each analyte. These interactions can be the result of either the combination of multiple specific biomarker recognition (specific binding) or multiple selective binding responses, known as chemical nose sensing. The versatility of the latter array-based sensing using NPs can facilitate the development of new personalized diagnostic methodologies in cancer diagnostics, a necessary evolution in the current healthcare system to better provide personalized treatments. This review will describe the basic principle of array-based sensors, along with providing examples of both invasive and noninvasive samples used in cancer diagnosis.

关键词： array-based sensing chemical nose sensing invasive noninvasive personalized diagnostics selective sensing

来源：评论

学校读者我要写书评

暂无评论

array-based sensing of Proteins and Bacteria By Using Multiple Luminescent Nanodots as Fluorescent Probes

引用

SMALL 2014年第18期10卷 3667-3671页

作者： Tao, Yu Ran, Xiang Ren, Jinsong Qu, Xiaogang Changchun Inst Appl Chem Biol Chem Lab State Key Lab Rare Earth Resource Utilizat Div Biol Inorgan Chem Changchun 130022 Peoples R China Chinese Acad Sci Grad Sch Changchun 130022 Peoples R China

Luminescent nanodots for protein sensing and discrimination of bacteria: Luminescent nanodots are applied as novel fluorescent probes in a sensing array. The sensing strategy uses graphene oxide (GO) for protein recognition, with displacement of fluorescent probes to generate the output. This sensing platform is a powerful tool to detect protein targets and discriminate bacteria.◆ (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

关键词： luminescent nanodots graphene oxide array-based sensing proteins bacteria

来源：评论

学校读者我要写书评

暂无评论

array-based "Chemical Nose" sensing in Diagnostics and Drug Discovery

引用

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2019年第16期58卷 5190-5200页

作者： Geng, Yingying Peveler, William J. Rotello, Vincent M. Univ Massachusetts Mol & Cellular Biol Program 710 N Pleast St Amherst MA 01003 USA Univ Massachusetts Dept Chem 710 N Pleast St Amherst MA 01003 USA Univ Glasgow Div Biomed Engn Sch Engn Glasgow G12 8LT Lanark Scotland Univ British Columbia Dept Chem 2036 Main Mall Vancouver BC V6T 1Z1 Canada

array-based sensor "chemical nose/tongue" platforms are inspired by the mammalian olfactory system. Multiple sensor elements in these devices selectively interact with target analytes;producing a distinct pattern of response and enabling analytes identification. This approach offers unique opportunities relative to "traditional" highly specific sensor elements such as antibodies. array-based sensors excel at distinguishing small changes in complex mixtures, and this capability is being leveraged for chemical biology studies and clinical pathology, enabled by a diverse toolkit of new molecular, bioconjugate and nanomaterial technologies. Innovation in the design and analysis of arrays provides a robust set of tools or advancing biomedical goals, including precision medicine.

关键词： array-based sensing biomedicine cancer cell detection diagnosis protein detection

来源：评论

学校读者我要写书评

暂无评论

Impulsive Magnetic Anomaly Detection At the 100-m Scale With an array of Induction Coil Magnetometers

IEEE SENSORS LETTERS

引用

IEEE SENSORS LETTERS 2025年第2期9卷

作者： Iivanainen, Joonas A. Read, Timothy S. Yang, Xianjin Junor, William Thrasher, Daniel A. Sandia Natl Labs Albuquerque NM 87123 USA Aalto Univ Sch Sci Dept Neurosci & Biomed Engn FI-00076 Aalto Finland Lawrence Livermore Natl Lab Livermore CA 94550 USA Los Alamos Natl Lab Los Alamos NM 87545 USA

We demonstrate magnetic anomaly detection (MAD) using an array of 24 commercial induction coil magnetometers with stand-off distances from a pulsed 99.8(3) kA & sdot;m (2) magnetic dipole source of 260-1200 m. The sparse array is used to estimate the magnetic dipole location, magnitude, and orientation. We demonstrate how independent component analysis (ICA) improves the accuracy and precision of the magnetometer array when estimating the dipole parameters. Using sensor responses recorded from individual source pulses, we estimate the dipole location to within 29 +/- 2 m, the magnitude to within 3 +/- 3 kA & sdot;m( 2) , and dipole orientation error to within 19 +/- 0.6(degrees) .

关键词： Magnetic sensors array-based sensing array-based sensing independent component analysis (ICA) independent component analysis (ICA) induction coil induction coil magnetic anomaly detection (MAD)

来源：评论

学校读者我要写书评

暂无评论

Time-resolved fluorescence sensor array for the discrimination of phosphate anions using transition metal dichalcogenide quantum dots and Tb(III)

引用

LUMINESCENCE 2023年第7期38卷 1339-1346页

作者： Behera, Pradipta Jaiswal, Komal De, Mrinmoy Indian Inst Sci Dept Organ Chem Bangalore Karnataka India Indian Inst Sci Dept Organ Chem Bangalore 560012 Karnataka India

Phosphate detection has garnered widespread attention due to its biological and environmental impact. Among several optical techniques, time-resolved fluorescence (TRF) provides a sensitive way for the discrimination of analytes in a complex mixture as it exhibits less interference from the background, therefore providing a high signal-to-noise ratio. The sensitization of rare earth metal (REM) ions by semiconducting quantum dots (QDs) can help the former overcome the drawback of low absorption coefficient, therefore allowing exploitation of the additional advantage of the REM, namely the long-excited state lifetime. Here, we have developed a TRF-based sensor array consisting of three QDs, i.e. MoS2, WS2 and MoSe2 as energy sensitizers for Tb3+ ions. Different QDs possess variable energy transfer abilities for Tb3+ ions. Therefore, they can be used to discriminate phosphates. It was also observed that CrO42- can competitively bind to Tb3+ and further enhance the efficiency of the sensor array so that it could discriminate six different phosphates at 200 mu M concentration in aqueous as well as serum medium with a detection limit of 10 mu M in aqueous medium. Therefore, the sensitivity of the TRF-based sensor array is rarely compromised in a complex mixture, which is advantageous over a fluorescence-based sensor array.

关键词： antenna effect array-based sensing linear discriminant analysis (LDA) phosphate sensing quantum dots

来源：评论

学校读者我要写书评

暂无评论

Plasmonic metasurface arrays for cross-reactive sensing 24

Plasmonic metasurface arrays for cross-reactive sensing

引用

Conference on Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV

作者： Sperling, Justin R. Poursat, Baptiste Christie, Iain Savage, Laurie Cuthill, Calum Aekbote, Badri L. McGuire, Katie Karimullah, Affar S. Robbie, Jill Sloan, William T. Gauchotte-Lindsay, Caroline Peveler, William J. Clark, Alasdair W. Univ Glasgow James Watt Sch Engn Glasgow Lanark Scotland Univ Glasgow Sch Chem Glasgow Lanark Scotland Univ Glasgow Sch Law Glasgow Lanark Scotland

ISBN: (纸本)9781510669307;9781510669291

In this manuscript we present the steps required to fabricate, modify, and measure a plasmonic metasurface array for cross-reactive sensing applications. Multiple arrays of gold nanostructures were fabricated using a standard top-down electron-beam lithography process and then enclosed in a microfluidic chamber. Partial-selectivity was then achieved by using different thiol chemistries to modify each array. Finally, measurements of various samples were taken using a custom-built microscope setup.

关键词： plasmonics sensor nanophotonics fabrication array-based sensing cross-reactive sensing metasurface

来源：评论

学校读者我要写书评

暂无评论

A Polymer-based Multichannel Sensor for Rapid Cell-based Screening of Antibiotic Mechanisms and Resistance Development

引用

ACS APPLIED MATERIALS & INTERFACES 2022年第23期14卷 27515-27522页

作者： Roy, Sohini Basu Nabawy, Ahmed Chattopadhyay, Aritra Nath Geng, Yingying Makabenta, Jessa Marie Gupta, Akash Rotello, Vincent M. Univ Massachusetts Dept Chem Amherst MA 01003 USA

Antibiotic resistance presents a critical threat to public health, necessitating the rapid development of novel antibiotics and an appropriate choice of therapeutics to combat refractory bacterial infections. Here, we report a high-throughput polymer-based sensor platform that rapidly (30 min) profiles mechanisms of antibiotic activity. The sensor array features three fluorophore-conjugated polymers that can detect subtle antibiotic-induced phenotypic changes on bacterial surfaces, generating distinct mechanism-based fluorescence patterns. Notably, discrimination of different generations of antibiotic resistance was achieved with high efficiency. This sensor platform combines trainability, simplicity, and rapid screening into a readily translatable platform.

关键词： multidrug-resistant bacteria array-based sensing antibiotics generation of resistance high-throughput screening

来源：评论

学校读者我要写书评

暂无评论

Optical tastebuds for water quality testing 23

Optical tastebuds for water quality testing

引用

Conference on Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIII

作者： Sperling, Justin R. Savage, Laurie Wilson, Liam T. Cuthill, Calum McGuire, Katie Robbie, Jill Sloan, William Gauchotte-Lindsay, Caroline Peveler, William J. Clark, Alasdair W. Univ Glasgow James Watt Sch Engn Glasgow Lanark Scotland Univ Glasgow Sch Chem Glasgow Lanark Scotland Univ Glasgow Sch Law Glasgow Lanark Scotland

ISBN: (纸本)9781510658493;9781510658509

To achieve the UN Sustainable Development Goal of universal access to clean water and sanitation, we need to rethink centralized water systems with global net-zero carbon and sustainability in mind. One approach is to develop scalable off-grid systems that are reliable and easy to use and maintain. A major challenge for such systems is translating the standard laboratory-based monitoring of centralized systems to a more sustainable and scalable model for regularly and routinely monitoring system outputs, which consist of complex mixtures with varying concentrations of molecules and ions in water. Here, we demonstrate a preliminary sensor that, once fully developed, could allow for point-of-use measurements with a single output to monitor. Rather than developing multiple sensors to monitor the levels of each individual component in the water, our label-free, array-based design mimics the biological system of taste. The sensor is comprised of an array of nano-tastebuds made of tailored plasmonic metasurfaces. The combination of different signals from each nano-tastebud to the same sample yields a unique fingerprint for that sample. Through training, these fingerprints build an identification model. By integrating a fully developed sensor into decentralized water systems, we seek to provide non-expert end-users with an easy-to-read output capable of warning of imminent system failures.

关键词： plasmonics water environment sensor nanophotonics array-based sensing cross-reactive sensing metasurface

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：