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检索条件"主题词=computational sequence analysis"
4 条 记 录,以下是1-10 订阅
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Azole resistance: patterns of amino acid substitutions in Candida sterol 14α-demethylase
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ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY 2025年 第5期118卷 1-9页
作者: Rao, R. Shyama Prasad Pinto, Larina Shastry, Rajesh P. Dakal, Tikam Chand Suravajhala, Prashanth Sashindran, V. K. Ghate, Sudeep D. NITTE Deemed Univ Ctr Bioinformat Mangaluru 575018 India NITTE deemed Univ KS Hegde Med Acad KSHEMA Cent Res Lab Mangaluru 575018 India Yenepoya Deemed Univ Yenepoya Res Ctr Div Microbiol & Biotechnol Mangaluru 575018 India Mohanlal Sukhadia Univ Dept Biotechnol Udaipur 313001 Rajasthan India Amrita Vishwa Vidyapeetham Amrita Sch Biotechnol Clappana 690525 Kerala India Bioclues Org Hyderabad 501511 India NITTE Deemed Univ KS Hegde Med Acad KSHEMA Dept Gen Med Mangaluru 575018 India Univ Edinburgh Sch Biol Sci Edinburgh Scotland
The emergence of azole-resistant Candida infections is a major concern. A key mechanism is the gain of resistance through amino acid substitutions in the sterol 14 alpha-demethylase, the main target of azole drugs. Wh... 详细信息
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analysis of Eukaryotic lincRNA sequences Indicates Signatures of Hindered Translation Linked to Selection Pressure
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MOLECULAR BIOLOGY AND EVOLUTION 2022年 第2期39卷 msab356-msab356页
作者: Brummer, Anneke Dreos, Rene Marques, Ana Claudia Bergmann, Sven Univ Lausanne Dept Computat Biol DBC Lausanne Switzerland Swiss Inst Bioinformat SIB Lausanne Switzerland Univ Lausanne Ctr Integrat Genom CIG Lausanne Switzerland Univ Cape Town Dept Integrat Biomed Sci Cape Town South Africa
Long intergenic noncoding RNAs (lincRNAs) represent a large fraction of transcribed loci in eukaryotic genomes. Although classified as noncoding, most lincRNAs contain open reading frames (ORFs), and it remains unclea... 详细信息
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Structure-function analysis of the ADAM family of disintegrin-like and metalloproteinase-containing proteins (review)
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JOURNAL OF PROTEIN CHEMISTRY 1999年 第4期18卷 447-465页
作者: Stone, AL Kroeger, M Sang, QXA Florida State Univ Dept Chem Tallahassee FL 32306 USA Florida State Univ Inst Mol Biophys Tallahassee FL 32306 USA
The ADAMs belong to a disintegrin-like and metalloproteinase-containing protein family that are zinc-dependent metalloproteinases. These proteins share all or some of the following domain structure: a signal peptide, ... 详细信息
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NEW-PROTEIN FUNCTIONS IN YEAST CHROMOSOME-VIII
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PROTEIN SCIENCE 1995年 第11期4卷 2424-2428页
作者: OUZOUNIS, C BORK, P CASARI, G SANDER, C EUROPEAN MOLEC BIOL LAB D-69012 HEIDELBERGGERMANY
The analysis of the 269 open reading frames of yeast chromosome VIII by computational methods has yielded 24 new significant sequence similarities to proteins of known function. The resulting predicted functions inclu... 详细信息
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