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An Ontology-Based Method to Link database integration and Data Mining within a Biomedical Distributed KDD

12th Conference on Artificial Intelligence in Medicine (AIME 2009)

作者： Perez-Rey, David Maojo, Victor Univ Politecn Madrid Dept Artificial Intelligence Fac Informat E-28660 Madrid Spain

ISBN: (纸本)9783642029752

Over the last years, collaborative research has been continuously growing in many scientific areas such as biomedicine. However, traditional Knowledge Discovery in databases (KDD) processes generally adopt centralized approaches that do not fully address many research needs in these distributed environments. This paper presents a method to improve traditional centralized KDD by adopting an ontology-based distributed model. Ontologies are used within this model: (i) is Virtual Schemas (VS) to solve structural heterogeneities in databases and (ii) as frameworks to guide automatic transformations when data is retrieved by users-Preprocessing Ontologies (PO). Both types of ontologies aim to facilitate data gathering and preprocessing while maintaining data source decentralization. This ontology-based approach allows to link database integration and data mining, improving final results, reusability and interoperability. The results obtained present improvements in outcome performance and new capabilities compared to traditional KDD processes.

关键词： database integration Distributed KDD Ontologies Preprocessing Data Mining

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Ontology mapping for a new database integration model using an ontology-driven mediated warehousing approach

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Research Journal of Applied Sciences, Engineering and Technology 2014年第13期7卷 2747-2755页

作者： Ahmed, Ali Hashim, Hafizullah Amin Alsamt, Faisal Salim, Naomie Ibrahim, Khalid Ahmed Almahy, Ibrahim Soft Computing Research Group Faculty of Computing Universiti Teknologi Malaysia 81310 Skudai Malaysia Faculty of Engineering Karary University 12304 Khartoum Sudan

Ontology mapping is a technique that has become very useful for matching semantics between ontologies or schemas that were designed independently of each other. The main goal of the ontology mapping is to enable interoperability between applications in distributed information systems based on heterogeneous ontologies. To achieve this goal it is necessary to formally define mapping rules between local data sources and ontologies and the notion of a mapping between ontologies. In this study, the authors proposed a new mapping approach, so that the ontologies have to be linked to actual information sources in order to support the integration process. In this approach, first, for each incorporated information source, a local ontology is generated to describe its semantics as well as the resulting mappings between the source and the local ontology, then the local ontologies are mapped to a global ontology using the mapping rule. © Maxwell Scientific Organization, 2014.

关键词： Data warehousing database integration Global ontology Local ontology Ontology mapping

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A Novel Approach for Multi-Source Heterogeneous database integration

A Novel Approach for Multi-Source Heterogeneous Database Int...

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IEEE International Conference on Machine Intelligence Research and Advancement (ICMIRA)

作者： Shelake, Vijay Maruti Bhojane, Varunakshi Sachin Yadavrao Tasgaonkar Coll Engn & Management Dept Informat Technol Bombay Maharashtra India Pillai Inst Informat Technol Dept Comp Engn Bombay Maharashtra India

ISBN: (纸本)9780769550138

Currently, there are different database management systems (DBMS) available and the integration between different database systems is required. There are tools and techniques available for schema matching, but most of them require manual intervention. However, in this paper, a new algorithm named as Multi-Source Heterogeneous database integration (MSHDI) is proposed which effectively performs 1:1 and M:1 database integration and determines semantic matches automatically. This paper introduces a novel experimentation with existing heterogeneous database systems such as Oracle, Microsoft SQL Server and Microsoft Excel for schema matching and data integration. In comparison with existing algorithms, this approach achieves full automation and better results on any real-world databases of same domain.

关键词： Heterogeneous database database integration Schema Matching

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Dart database Grid: A dynamic, adaptive, RDF-mediated, Transparent approach to database integration for semantic web

Dart Database Grid: A dynamic, adaptive, RDF-mediated, Trans...

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7th Asia-Pacific Web Conference

作者： Wu, ZH Chen, HJ Mao, YX Zheng, GZ Zhejiang Univ Coll Comp Sci Hangzhou 310027 Peoples R China

ISBN: (纸本)354025207X

This paper demonstrated the Dart database Grid system developed by Grid Research Center of Zhejiang University. Dart database Grid is built upon several Semantic Web standards and the Globus grid toolkits. It is mainly intended to provide a Dynamic, Adaptive, RDF-mediated and Transparent (DART) approach to database integration for semantic web. This work has been applied to integrate data resources from the application domain of Traditional Chinese Medicine.

关键词： semantic web Grid computing database integration ontology

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Heterogeneous database integration Middleware Based on Web Services

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Physics Procedia 2012年 24卷 877-882页

作者： Xianmin Wei Computer and Communication Engineering School Weifang UniversityWeifang China

With the company further accelerating the process of information, the heterogeneity problem of each business system database is more and more salient. How to effectively use these historical data, integration of legacy systems, become a hot spot of integration field. In this paper, how to effectively address heterogeneity of data distribution, to achieve customer access, while maintaining the autonomy of the local system for the objectives of heterogeneous database integration middleware based on Web Services *** show that middleware solution has certain feasibility and practicality.

关键词： Web Services XML middleware database integration

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A database integration Method for Small and Medium Information System

A Database Integration Method for Small and Medium Informati...

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2010 Second International Conference on E-Learning, E-Business, Enterprise Information Systems, and E-Government (EEEE 2010)

作者： Bing Wang Zhejiang GongShang University, 310018, Hangzhou, Zhejiang, China

The paper presents a database integration method named MysqlInside which mainly for small and medium information system, describes its composition and structure, introduces some key attributes and functions of its components, and gives the core code in Java language for example. With the performance advantages of Mysql itself, MysqlInside is easy to use and has fully competent for small and medium information system’s database application requirements.

关键词： database integration small and medium information system Mysql Java

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Heterogeneous database integration Middleware Based on Web Services

Heterogeneous Database Integration Middleware Based on Web S...

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2010 The 3rd International Conference on Power Electronics and Intelligent Transportation System (PEITS 2010)

作者： Xianmin Wei Computer and Communication Engineering School Weifang University Weifang,China

With the company further accelerating the process of information,the heterogeneity problem of each business system database is more and more *** to effectively use these historical data,integration of legacy systems,become a hot spot of integration *** this paper,how to effectively address heterogeneity of data distribution,to achieve customer access,while maintaining the autonomy of the local system for the objectives of heterogeneous database integration middleware based on Web Services *** show that middleware solution has certain feasibility and practicality.

关键词： Web Services XML middleware database integration

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A database integration Method for Small and Medium Information System

A Database Integration Method for Small and Medium Informati...

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The 2011 International Conference on Computing,Information and Control(ICCIC 2011)

作者： Bing Wang Zhejiang Gong Shang University

The paper presents a database integration method named Mysql Inside which mainly for small and medium information system, describes its composition and structure, introduces some key attributes and functions of its components, and gives the core code in Java language for example. With the performance advantages of Mysql itself, Mysql Inside is easy to use and has fully competent for small and medium information system's database application requirements.

关键词： database integration small and medium information system Mysql Java

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Digital Microscopy for Boosting database integration and Analysis in TMA Studies

Digital Microscopy for Boosting Database Integration and Ana...

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作者： Tibor Krenacs Levente Ficsor Sebestyen Viktor Varga Vivien Angeli Bela Molnar

The enormous amount of clinical, pathological, and staining data to be linked, analyzed, and correlated in a tissue microarray (TMA) project makes digital slides ideal to be integrated into TMA database systems. With the help of a computer and dedicated software tools, digital slides offer dynamic access to microscopic information at any magnification with easy navigation, annotation, measurement, and archiving features. Advanced slide scanners work both in transmitted light and fluorescent modes to support biomarker testing with immunohistochemistry, immunofluorescence or fluorescence in situ hybridization (FISH). Currently, computer-driven integrated systems are available for creating TMAs, digitalizing TMA slides, linking sample and staining data, and analyzing their results. Digital signals permit image segmentation along color, intensity, and size for automated object quantification where digital slides offer superior imaging features and batch processing. In this chapter, the workflow and the advantages of digital TMA projects are demonstrated through the project-based MIRAX system developed by 3DHISTECH and supported by Zeiss. The enhanced features of digital slides compared with those of still images can boost integration and intelligence in TMA database management systems, offering essential support for high-throughput biomarker testing, for example, in tumor progression/prognosis, drug discovery, and target therapy research. less

关键词： Microscopy Microarray Image Analysis Immunohistochemistry Immunofluorescence FISH Statistical Calculation Immunostaining In Situ Hybridization Image segmentation Correlation analysis database integration Validated scoring

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VaProS: a database-integration approach for protein/genome information retrieval

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Journal of Structural and Functional Genomics 2016年第4期17卷 69-81页

作者： Gojobori, Takashi Ikeo, Kazuho Katayama, Yukie Kawabata, Takeshi Kinjo, Akira R. Kinoshita, Kengo Kwon, Yeondae Migita, Ohsuke Mizutani, Hisashi Muraoka, Masafumi Nagata, Koji Omori, Satoshi Sugawara, Hideaki Yamada, Daichi Yura, Kei Computational Bioscience Research Center Biological and Environmental Sciences and Engineering King Abdullah University of Science and Technology Thuwal 23955-6900 Saudi Arabia National Institute of Genetics Shizuoka Mishima 411-8540 Japan Graduate School of Agricultural and Life Sciences University of Tokyo Bunkyo Tokyo 113-8657 Japan Institute for Protein Research Osaka University Suita Osaka 565-0871 Japan Graduate School of Information Sciences Tohoku University Miyagi Sendai 980-8597 Japan Tohoku Medical Megabank Organization Tohoku University Miyagi Sendai 980-8573 Japan Department of Maternal-Fetal Biology National Research Institute for Child Health and Development Setagaya Tokyo 157-8535 Japan Department of Pediatrics St. Marianna University School of Medicine Miyamae Kawasaki 216-8511 Japan Center for Informational Biology Ochanomizu University 2-1-1 Otsuka Bunkyo Tokyo 112-8610 Japan

Life science research now heavily relies on all sorts of databases for genome sequences, transcription, protein three-dimensional (3D) structures, protein–protein interactions, phenotypes and so forth. The knowledge accumulated by all the omics research is so vast that a computer-aided search of data is now a prerequisite for starting a new study. In addition, a combinatory search throughout these databases has a chance to extract new ideas and new hypotheses that can be examined by wet-lab experiments. By virtually integrating the related databases on the Internet, we have built a new web application that facilitates life science researchers for retrieving experts’ knowledge stored in the databases and for building a new hypothesis of the research target. This web application, named VaProS, puts stress on the interconnection between the functional information of genome sequences and protein 3D structures, such as structural effect of the gene mutation. In this manuscript, we present the notion of VaProS, the databases and tools that can be accessed without any knowledge of database locations and data formats, and the power of search exemplified in quest of the molecular mechanisms of lysosomal storage disease. VaProS can be freely accessed at http://***/vapros/. © 2016, The Author(s).

关键词： Big data analysis database integration Lysosomal storage disease Protein 3D structure

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