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检索条件"主题词=lectin microarray"
107 条 记 录,以下是1-10 订阅
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lectin microarray based glycan profiling of exosomes for dynamic monitoring of colorectal cancer progression
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ANALYTICA CHIMICA ACTA 2024年 1316卷 342819页
作者: Sun, Xudong Chen, Bowen Shan, Yongjie Jian, Minghong Wang, Zhenxin Chinese Acad Sci Changchun Inst Appl Chem State Key Lab Electroanalyt Chem Changchun 130022 Peoples R China Univ Sci & Technol China Sch Appl Chem & Engn Hefei 230026 Peoples R China First Hosp Jilin Univ Gen Surg Ctr Dept Thyroid Surg Changchun 130021 Peoples R China Chinese Acad Sci Changchun Inst Appl Chem Natl Analyt Res Ctr Electrochem & Spect Changchun 130022 Peoples R China Chinese Acad Sci Changchun Inst Appl Chem 5625 Ren Min St Changchun 130022 Peoples R China
Background: Exosomes, as emerging biomarkers in liquid biopsies in recent years, offer profound insights into cancer diagnostics due to their unique molecular signatures. The glycosylation profiles of exosomes have em... 详细信息
来源: 评论
Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2025年 第5期417卷 973-988页
作者: Nagai-Okatani, Chiaki Tomioka, Azusa Tominaga, Daisuke Sakaue, Hiroaki Kuno, Atsushi Kaji, Hiroyuki Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Mol & Cellular Glycoprote Res Grp Tsukuba Ibaraki 3058565 Japan Nagoya Univ Inst Glycocore Res iGCORE Furo Cho Nagoya Aichi 4648601 Japan
To understand the biological and pathological functions of protein glycosylation, the glycan heterogeneities for each glycosite in a single glycoprotein need to be elucidated depending on the type and status of cells.... 详细信息
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Glycomic profiling of parathyroid neoplasms via lectin microarray analysis
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ENDOCRINE 2025年 第3期87卷 1224-1234页
作者: Zheng, Qingyuan Cui, Ming Xiao, Jinheng Yang, Sen Chen, Tianqi Shi, Yanan Hu, Ya Liao, Quan Chinese Acad Med Sci & Peking Union Med Coll Peking Union Med Coll Hosp Dept Gen Surg State Key Lab Complex Severe & Rare Dis Beijing Peoples R China Chinese Acad Med Sci & Peking Union Med Coll Peking Union Med Coll Hosp Inst Clin Med Biomed EngnFac Natl Infrastruct Translat Med Beijing Peoples R China
PurposeParathyroid carcinoma (PC) is a rare malignancy with a poor prognosis. Diagnosis of PC is often difficult in clinical practice and efficient diagnostic markers are still needed for differential diagnosis. Aberr... 详细信息
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Combinatorial Approach with Mass Spectrometry and lectin microarray Dissected Site-Specific Glycostem and Glycoleaf Features of the Virion-Derived Spike Protein of Ancestral and γ Variant SARS-CoV-2 Strains
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JOURNAL OF PROTEOME RESEARCH 2024年 第4期23卷 1408-1419页
作者: Hiono, Takahiro Sakaue, Hiroaki Tomioka, Azusa Kaji, Hiroyuki Sasaki, Michihito Orba, Yasuko Sawa, Hirofumi Kuno, Atsushi Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Mol & Cellular Glycoprote Res Grp Tsukuba Ibaraki 3058565 Japan Hokkaido Univ One Hlth Res Ctr Sapporo Hokkaido 0600818 Japan Hokkaido Univ Fac Vet Med Dept Dis Control Lab Microbiol Sapporo Hokkaido 0600818 Japan Hokkaido Univ Int Inst Zoonosis Control Int Collaborat Unit Sapporo Hokkaido 0010020 Japan Hokkaido Univ Inst Vaccine Res & Dev HU IVReD Sapporo Hokkaido 0010021 Japan Hokkaido Univ Int Inst Zoonosis Control Div Mol Pathobiol Sapporo Hokkaido 0010020 Japan
The coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted public health globally. As the glycosylation of viral envelope glycoproteins is strongl... 详细信息
来源: 评论
Changes in serum immunoglobulin G glycosylation patterns for antiphospholipid syndrome patients with lectin microarray
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SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2024年 第6期99卷 e13366-e13366页
作者: Wang, Yifei Li, Siting Meng, Jingjing Yu, Rui Wang, Qian Tian, Xinping Li, Mengtao Zeng, Xiaofeng Zhao, Jiulang Hu, Chaojun Chinese Acad Med Sci & Peking Union Med Coll Dept Rheumatol & Clin Immunol Beijing Peoples R China Minist Sci & Technol Natl Clin Res Ctr Dermatol & Immunol Dis NCRC DID Beijing Peoples R China Minist Educ Key Lab Rheumatol & Clin Immunol Beijing Peoples R China Zhengzhou Univ Affiliated Hosp 5 Dept Clin Lab Zhengzhou Peoples R China Minist Educ Key Lab Rheumatol & Clin Immunol 1 Shuaifuyuan Beijing 100730 Peoples R China
Antiphospholipid syndrome is a rare autoimmune disease characterized by persistent antiphospholipid antibodies. Immunoglobulin G plays a vital role in disease progression, with its structure and function affected by g... 详细信息
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A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
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MABS 2024年 第1期16卷 2304268页
作者: Luo, Shen Zhang, Baolin Ctr Drug Evaluat & Res FDA Off Pharmaceut Qual Silver Spring MD USA FDA Ctr Drug Evaluat & Res Off Pharmaceut Qual Silver Spring MD 20993 USA
Glycosylation plays a crucial role in determining the quality and efficacy of therapeutic antibodies. This necessitates a thorough analysis and monitoring process to ensure consistent product quality during manufactur... 详细信息
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LM-GlycomeAtlas Ver. 2.0: An Integrated Visualization for lectin microarray-based Mouse Tissue Glycome Mapping Data with lectin Histochemistry
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JOURNAL OF PROTEOME RESEARCH 2021年 第4期20卷 2069-2075页
作者: Nagai-Okatani, Chiaki Zou, Xia Fujita, Noriaki Sogabe, Isami Arakawa, Kouiti Nagai, Misugi Angata, Kiyohiko Zhang, Yan Aoki-Kinoshita, Kiyoko F. Kuno, Atsushi Shanghai Jiao Tong Univ Shanghai Ctr Syst Biomed Minist Educ Key Lab Syst Biomed Shanghai 200240 Peoples R China Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Mol & Cellular Glycoprote Res Grp Tsukuba Ibaraki 3058565 Japan Soka Univ Glycan & Life Sci Integrat Ctr GaLSIC Fac Sci & Engn Hachioji Tokyo 1928577 Japan
Laser microdissection-assisted lectin microarray has been used to obtain quantitative and qualitative information on glycans on proteins expressed in microscopic regions of formalin-fixed paraffin-embedded tissue sect... 详细信息
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Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study
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BMC CANCER 2020年 第1期20卷 192-192页
作者: Takayama, Hiroomi Ohta, Masayuki Iwashita, Yukio Uchida, Hiroki Shitomi, Yuki Yada, Kazuhiro Inomata, Masafumi Oita Univ Fac Med Dept Gastroenterol & Pediat Surg 1-1 IdaigaokaHasama Machi Oita 8795593 Japan Oita Univ Global Oita Med Adv Res Ctr Hlth Oita Japan
BackgroundAltered glycosylation associated with hepatocellular carcinoma (HCC) is well documented. However, few reports have investigated the association between dedifferentiation and glycosylation. Therefore, the aim... 详细信息
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High-precision multiclass cell classification by supervised machine learning on lectin microarray data
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REGENERATIVE THERAPY 2020年 15卷 195-201页
作者: Shibata, Mayu Okamura, Kohji Yura, Kei Umezawa, Akihiro Natl Ctr Child Hlth & Dev Dept Reprod Biol Tokyo 1578535 Japan Ochanomizu Univ Grad Sch Humanities & Sci Tokyo 1128610 Japan Natl Ctr Child Hlth & Dev Dept Syst BioMed Tokyo 1578535 Japan Waseda Univ Sch Adv Sci & Engn Tokyo 1620041 Japan
Introduction: Establishment of a cell classification platform for evaluation and selection of human pluripotent stem cells (hPSCs) is of great importance to assure the efficacy and safety of cell-based therapy. In our... 详细信息
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Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
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AGING CELL 2020年 第8期19卷 e13190-e13190页
作者: Oinam, Lalhaba Changarathil, Gopakumar Raja, Erna Ngo, Yen Xuan Tateno, Hiroaki Sada, Aiko Yanagisawa, Hiromi Univ Tsukuba Life Sci Ctr Survival Dynam Tsukuba Adv Res Alliance TARA Tsukuba Ibaraki Japan Univ Tsukuba Sch Integrat & Global Majors PhD Program Human Biol Tsukuba Ibaraki Japan Univ Tsukuba Grad Sch Comprehens Human Sci Tsukuba Ibaraki Japan Kumamoto Univ Int Res Ctr Med Sci IRCMS Kumamoto Japan Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Tsukuba Cent 61-1-1 Higashi Tsukuba Ibaraki 3058566 Japan Univ Tsukuba Fac Med Tsukuba Ibaraki Japan
Aging in the epidermis is marked by a gradual decline in barrier function, impaired wound healing, hair loss, and an increased risk of cancer. This could be due to age-related changes in the properties of epidermal st... 详细信息
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