咨询与建议

限定检索结果

文献类型

  • 594 篇 期刊文献
  • 170 篇 会议
  • 6 篇 学位论文

馆藏范围

  • 770 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 548 篇 工学
    • 385 篇 计算机科学与技术...
    • 134 篇 生物工程
    • 111 篇 电气工程
    • 59 篇 生物医学工程(可授...
    • 39 篇 控制科学与工程
    • 23 篇 软件工程
    • 21 篇 信息与通信工程
    • 10 篇 材料科学与工程(可...
    • 10 篇 化学工程与技术
    • 9 篇 仪器科学与技术
    • 5 篇 环境科学与工程(可...
    • 4 篇 电子科学与技术(可...
    • 3 篇 机械工程
    • 3 篇 冶金工程
  • 433 篇 理学
    • 333 篇 生物学
    • 133 篇 统计学(可授理学、...
    • 60 篇 数学
    • 25 篇 化学
    • 19 篇 系统科学
    • 8 篇 物理学
    • 5 篇 生态学
  • 156 篇 医学
    • 73 篇 基础医学(可授医学...
    • 41 篇 临床医学
    • 18 篇 药学(可授医学、理...
    • 12 篇 公共卫生与预防医...
  • 117 篇 农学
    • 28 篇 作物学
  • 52 篇 管理学
    • 41 篇 管理科学与工程(可...
    • 9 篇 公共管理
  • 30 篇 经济学
    • 30 篇 应用经济学
  • 3 篇 文学
    • 3 篇 新闻传播学
  • 2 篇 教育学
  • 1 篇 艺术学

主题

  • 770 篇 microarray data
  • 103 篇 feature selectio...
  • 60 篇 classification
  • 58 篇 gene selection
  • 48 篇 gene expression
  • 34 篇 bioinformatics
  • 31 篇 clustering
  • 30 篇 cancer classific...
  • 23 篇 machine learning
  • 20 篇 genetic algorith...
  • 17 篇 support vector m...
  • 17 篇 data mining
  • 17 篇 biclustering
  • 16 篇 feature extracti...
  • 16 篇 false discovery ...
  • 15 篇 cancer
  • 15 篇 gene ontology
  • 13 篇 differentially e...
  • 13 篇 breast cancer
  • 13 篇 genetic algorith...

机构

  • 7 篇 jadavpur univ de...
  • 6 篇 univ rochester d...
  • 5 篇 indian stat inst...
  • 5 篇 hefei univ techn...
  • 4 篇 nehu it dept shi...
  • 4 篇 gimt ece dept kr...
  • 4 篇 chuzhou univ sch...
  • 4 篇 univ calcutta cs...
  • 3 篇 royal thai air f...
  • 3 篇 osaka prefecture...
  • 3 篇 res ctr comp sci...
  • 3 篇 osaka prefecture...
  • 3 篇 georgia inst tec...
  • 3 篇 mohamed boudiaf ...
  • 3 篇 mit dept elect e...
  • 3 篇 xiamen univ dept...
  • 3 篇 univ calcutta de...
  • 3 篇 northeastern uni...
  • 3 篇 northeastern uni...
  • 3 篇 univ teknol mala...

作者

  • 11 篇 deris safaai
  • 9 篇 yoshioka michifu...
  • 9 篇 omatu sigeru
  • 9 篇 mohamad mohd sab...
  • 8 篇 saha goutam
  • 7 篇 wang aiguo
  • 7 篇 sarkar ram
  • 6 篇 an ning
  • 6 篇 yakovlev andrei
  • 6 篇 li wei
  • 6 篇 mandal sudip
  • 5 篇 xie weidong
  • 5 篇 dash rasmita
  • 5 篇 klebanov lev
  • 5 篇 pal rajat kumar
  • 5 篇 boongoen tossapo...
  • 4 篇 moorthy kohbalan
  • 4 篇 liu kun-hong
  • 4 篇 hong qingqi
  • 4 篇 chen guilin

语言

  • 737 篇 英文
  • 32 篇 其他
  • 1 篇 中文
检索条件"主题词=microarray Data"
770 条 记 录,以下是511-520 订阅
排序:
Hierarchical tree snipping: clustering guided by prior knowledge
收藏 引用
BIOINFORMATICS 2007年 第24期23卷 3335-3342页
作者: Dotan-Cohen, Dikla Melkman, Avraham A. Kasif, Simon Ben Gurion Univ Negev Dept Comp Sci IL-84105 Beer Sheva Israel Childrens Hosp Dept Biomed Engn Boston MA 02115 USA Childrens Hosp Ctr Adv Genom Technol Boston MA 02115 USA Childrens Hosp Bioinformat Program Boston MA 02115 USA Childrens Hosp Harvard MIT Program Hlth Sci & Technol Boston MA 02115 USA
Motivation: Hierarchical clustering is widely used to cluster genes into groups based on their expression similarity. This method first constructs a tree. Next this tree is partitioned into subtrees by cutting all edg... 详细信息
来源: 评论
A new hybrid method for gene selection
收藏 引用
PATTERN ANALYSIS AND APPLICATIONS 2011年 第1期14卷 1-8页
作者: Cai, Ruichu Hao, Zhifeng Yang, Xiaowei Huang, Han Guangdong Univ Technol Fac Comp Sci Guangzhou 510006 Guangdong Peoples R China S China Univ Technol Coll Math Sci Guangzhou 510640 Peoples R China S China Univ Technol Sch Software Engn Guangzhou 510006 Guangdong Peoples R China City Univ Hong Kong Coll Business Dept Management Sci Hong Kong Hong Kong Peoples R China
Gene selection is a significant preprocessing of the discriminant analysis of microarray data. The classical gene selection methods can be classified into three categories: the filters, the wrappers and the embedded m... 详细信息
来源: 评论
Identify the signature genes for diagnose of uveal melanoma by weight gene co-expression network analysis
收藏 引用
International Journal of Ophthalmology(English edition) 2015年 第2期8卷 269-274页
作者: Kai Shi Zhi-Tong Bing Gui-Qun Cao Ling Guo Ya-Na Cao Hai-Ou Jiang Mei-Xia Zhang Department of Ophthalmology West China HospitalSichuan University Molecular Medicine Research Center West China HospitalSichuan University Institute of Modern Physics Chinese Academy of Sciences College of Electrical Engineering Northwest University for Nationalities
AIM: To identify and understand the relationship between co-expression pattern and clinic traits in uveal melanoma, weighted gene co-expression network analysis(WGCNA) is applied to investigate the gene expression lev... 详细信息
来源: 评论
An effective measure corresponding to biological significance
收藏 引用
NETWORK MODELING AND ANALYSIS IN HEALTH INFORMATICS AND BIOINFORMATICS 2014年 第1期3卷 1-15页
作者: Goyal, Ankita Ahmed, Hasin A. Bhattacharyya, Dhruba K. Tezpur Univ Dept CSE Tezpur 784028 Assam India
Shifting and scaling correlations are correspondent of biological significance in gene expression data analysis. Recent works have mentioned about the significance of negative correlation as well. In this paper, we di... 详细信息
来源: 评论
Significance analysis of functional categories in gene expression studies: a structured permutation approach
收藏 引用
BIOINFORMATICS 2005年 第9期21卷 1943-1949页
作者: Barry, WT Nobel, AB Wright, FA Univ N Carolina Dept Biostat Chapel Hill NC 27599 USA Univ N Carolina Dept Stat Chapel Hill NC 27599 USA
Motivation: In high-throughput genomic and proteomic experiments, investigators monitor expression across a set of experimental conditions. To gain an understanding of broader biological phenomena, researchers have un... 详细信息
来源: 评论
Mixture model on the variance for the differential analysis of gene expression data
收藏 引用
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS 2005年 第1期54卷 31-50页
作者: Delmar, P Robin, S Tronik-Le Roux, D Daudin, JJ Lab Fournier SA F-21121 Daix France Ecole Cent Paris Chatenay Malabry France INRA Paris France Commisariat Energie Atom Evry France
In microarray experiments, accurate estimation of the gene variance is a key step in the identification of differentially expressed genes. Variance models go from the too stringent homoscedastic assumption to the over... 详细信息
来源: 评论
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
收藏 引用
MOLECULAR CELL 2004年 第4期16卷 521-535页
作者: Hayakawa, J Mittal, S Wang, Y Korkmaz, KS Adamson, E English, C Omichi, M McClelland, M Mercola, D Sidney Kimmel Canc Ctr San Diego CA 92121 USA Burnham Inst La Jolla CA 92037 USA Univ Calif San Diego Rebecca & John Moores Canc Ctr La Jolla CA 92093 USA Osaka Univ Sch Med Dept Obstet & Gynecol Suita Osaka 5650871 Japan
The NH2-terminal Jun kinases (JNKs) function in diverse roles through phosphorylation and activation of AP-1 components including ATF2 and c-Jun. However, the genes that mediate these processes are poorly understood. ... 详细信息
来源: 评论
A review of feature selection techniques in bioinformatics
收藏 引用
BIOINFORMATICS 2007年 第19期23卷 2507-2517页
作者: Saeys, Yvan Inza, Inaki Larranaga, Pedro VIB Dept Plant Syst Biol B-9052 Ghent Belgium Univ Ghent Dept Mol Genet Bioinformat & Evolutionary Genom Grp B-9052 Ghent Belgium Univ Basque Country Fac Comp Sci Dept Comp Sci & Artificial Intelligence San Sebastian Spain
Feature selection techniques have become an apparent need in many bioinformatics applications. In addition to the large pool of techniques that have already been developed in the machine learning and data mining field... 详细信息
来源: 评论
Identification of unique key genes and miRNAs in latent tuberculosis infection by network analysis
收藏 引用
MOLECULAR IMMUNOLOGY 2019年 112卷 103-114页
作者: Lin, Yan Zhang, Yuwei Yu, Huiyuan Tian, Ruonan Wang, Guoqing Li, Fan Jilin Univ Coll Basic Med Chinese Minist Educ Dept PathogenobiolKey Lab Zoonosis 126 Xinmin St Changchun 130021 Jilin Peoples R China Jilin Univ Minist Educ Key Lab Bion Engn Changchun 130021 Jilin Peoples R China Jilin Univ Engn Res Ctr Med Biomat Jilin Prov Changchun 130021 Jilin Peoples R China Jilin Univ Key Lab Biomed Mat Jilin Prov Changchun 130021 Jilin Peoples R China Jilin Univ Sch Publ Hlth Changchun 130021 Jilin Peoples R China State Key Lab Pathogenesis Prevent & Treatment Hi Urumqi Xinjiang Peoples R China
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (***). New cases are now mainly caused by the progression of latent tuberculosis infection (LTBI). Thus, methods to diagnose and t... 详细信息
来源: 评论
Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines
收藏 引用
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH 2015年 第1期10卷 1-9页
作者: Yang, Xiao-rong Xiong, Yan Duan, Hong Gong, Ren-rong Sichuan Univ West China Hosp Dept Operat Room Chengdu 610041 Sichuan Peoples R China Sichuan Univ West China Hosp Dept Orthoped Chengdu 610041 Sichuan Peoples R China
Background: This study aimed to better understand the mechanisms underlying methotrexate (MTX)-resistance in osteosarcoma. Methods: The raw transcription microarray data GSE16089 collected from three MTX-sensitive ost... 详细信息
来源: 评论