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检索条件"主题词=microarray Data"
770 条 记 录,以下是531-540 订阅
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A Copula-Based Algorithm for Discovering Patterns of Dependent Observations
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JOURNAL OF CLASSIFICATION 2012年 第1期29卷 50-75页
作者: Di Lascio, F. Marta L. Giannerini, Simone Univ Bologna Dipartimento Sci Stat I-40126 Bologna Italy
The main aim of this work is the study of clustering dependent data by means of copula functions. Copulas are popular multivariate tools whose importance within clustering methods has not been investigated yet in deta... 详细信息
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To how many simultaneous hypothesis tests can normal, student's t or bootstrap calibration be applied?
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JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION 2007年 第480期102卷 1282-1288页
作者: Fan, Jianqing Hall, Peter Yao, Qiwei Princeton Univ Dept Operat Res & Financial Engn Princeton NJ 08544 USA Acad Math & Syst Sci Ctr Stat Res Beijing Peoples R China Univ Melbourne Dept Math Stat Melbourne Vic 3010 Australia
In the analysis of microarray data, and in some other contemporary statistical problems, it is not uncommon to apply hypothesis tests in a highly simultaneous way. The number, N say, of tests used can be much larger t... 详细信息
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Transcriptional cross talk between the forkhead transcription factor forkhead box O1A and the progesterone receptor coordinates cell cycle regulation and differentiation in human endometrial stromal cells
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MOLECULAR ENDOCRINOLOGY 2007年 第10期21卷 2334-2349页
作者: Takano, Masashi Lu, Zhenxiao Goto, Tomoko Fusi, Luca Higham, Jenny Francis, Julia Withey, Anna Hardt, Jennifer Cloke, Brianna Stavropoulou, Alexandra V. Ishihara, Osamu Lam, Eric W. -F. Unterman, Terry G. Brosens, Jan J. Kim, J. Julie Northwestern Univ Dept Obstet & Gynecol Div Reprod Biol Res Chicago IL 60611 USA Univ Illinois Coll Med Dept Physiol & Biophys Chicago IL 60612 USA Univ Illinois Coll Med Dept Med Chicago IL 60612 USA Vet Affairs Chicago Healthcare Syst Chicago IL 60612 USA Hammersmith Hosp Imperial Coll London Inst Reprod & Dev Biol London W12 0HS England Hammersmith Hosp Imperial Coll London Canc Res UK Labs London W12 0HS England Hammersmith Hosp Imperial Coll London Sect Canc Cell Biol London W12 0HS England Hammersmith Hosp Imperial Coll London Dept Oncol London W12 0HS England St Marys Hosp Univ London Imperial Coll Sci Technol & Med Dept Obstet & Gynaecol London W2 1PG England Saitama Med Sch Dept Obstet & Gynecol Moroyama Saitama 3500495 Japan
Differentiation of human endometrial stromal cells ( HESCs) into decidual cells is associated with induction of the forkhead transcription factor forkhead box O1A ( FOXO1). We performed a genomic screen to identify de... 详细信息
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Electronically subtracting expression patterns from a mixed cell population
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BIOINFORMATICS 2007年 第24期23卷 3328-3334页
作者: Gosink, Mark M. Petrie, Howard T. Tsinoremas, Nicholas F. Scripps Florida Jupiter FL 33458 USA Univ Miami Miller Sch Med Ctr Computat Sci Miami FL 33136 USA
Motivation: Biological samples frequently contain multiple cell-types that each can play a crucial role in the development and/or regulation of adjacent cells or tissues. The search for biomarkers, or expression patte... 详细信息
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Merging two gene-expression studies via cross-platform normalization
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BIOINFORMATICS 2008年 第9期24卷 1154-1160页
作者: Shabalin, Andrey A. Tjelmeland, Hakon Fan, Cheng Perou, Charles M. Nobel, Andrew B. Univ N Carolina Dept Stat & Operat Res Chapel Hill NC 27599 USA Norwegian Univ Sci & Technol Dept Math Sci N-7034 Trondheim Norway Univ N Carolina Lineberger Comprehens Canc Ctr Chapel Hill NC 27599 USA Univ N Carolina Dept Pathol & Lab Med Chapel Hill NC 27599 USA Univ N Carolina Dept Genet Chapel Hill NC 27599 USA
Motivation: Gene-expression microarrays are currently being applied in a variety of biomedical applications. This article considers the problem of how to merge datasets arising from different gene-expression studies o... 详细信息
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Mining co-regulated gene profiles for the detection of functional associations in gene expression data
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BIOINFORMATICS 2007年 第15期23卷 1927-1935页
作者: Gyenesei, Attila Wagner, Ulrich Barkow-Oesterreicher, Simon Stolte, Etzard Schlapbach, Ralph Univ ETH Zurich Funct Genom Ctr Zurich CH-8057 Zurich Switzerland Unilever Res Labs Vlaardingen Knowledge & Data Anal NL-3130 AC Vlaardingen Netherlands GenoSyst Ltd Bioinformat Unit FIN-20520 Turku Finland
Motivation: Association pattern discovery (APD) methods have been successfully applied to gene expression data. They find groups of co-regulated genes in which the genes are either up- or down-regulated throughout the... 详细信息
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Semiparametric estimation of a two-component mixture model where one component is known
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SCANDINAVIAN JOURNAL OF STATISTICS 2006年 第4期33卷 733-752页
作者: Bordes, Laurent Delmas, Celine Vandekerkhove, Pierre Univ Marne Vallee LAMA F-77454 Champs Sur Marne 2 Marne La Vallee France Univ Technol Compiegne LMAC F-60206 Compiegne France
We consider a two-component mixture model where one component distribution is known while the mixing proportion and the other component distribution are unknown. These kinds of models were first introduced in biology ... 详细信息
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Cancer onset and progression: A genome-wide, nonlinear dynamical systems perspective on onconetworks
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JOURNAL OF THEORETICAL BIOLOGY 2007年 第2期246卷 234-244页
作者: Qu, K. Haidar, A. Abi Fan, J. Ensman, L. Tuncay, K. Jolly, M. Ortoleva, P. Indiana Univ Ctr Cell & Virus Theory Dept Chem Bloomington IN 47405 USA
It is hypothesized that the many human cell types corresponding to multiple states is supported by an underlying nonlinear dynamical system (NDS) of transcriptional regulatory network (TRN) processes. This hypothesis ... 详细信息
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Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process
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BIOINFORMATICS 2007年 第16期23卷 2096-2103页
作者: Elo, Laura L. Jaervenpaeae, Henna Oresic, Matej Lahesmaa, Riitta Aittokallio, Tero Univ Turku Dept Math FI-20014 Turku Finland Turku Ctr Biotechnol FI-20521 Turku Finland VTT Biotechnol FI-02044 Espoo Finland Inst Pasteur Syst Biol Unit F-75724 Paris France
Motivation: Coexpression networks have recently emerged as a novel holistic approach to microarray data analysis and interpretation. Choosing an appropriate cutoff threshold, above which a gene-gene interaction is con... 详细信息
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Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer
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EURASIP JOURNAL ON BIOINFORMATICS AND SYSTEMS BIOLOGY 2016年 第1期2016卷 6页
作者: Solvang, Hiroko K. Frigessi, Arnoldo Kaveh, Fateme Riis, Margit L. H. Luders, Torben Bukholm, Ida R. K. Kristensen, Vessela N. Andreassen, Bettina K. Inst Marine Res Dept Marine Mammals C Sundts Gate 64 N-5004 Bergen Norway Univ Oslo Inst Basic Med Sci Dept Biostat Oslo Norway Stat Innovat Sfi 2 Oslo Norway Oslo Univ Hosp Ulleval Med Genet Dept Oslo Norway Akershus Univ Hosp Dept Surg Lorenskog Norway Akershus Univ Hosp Inst Clin Med Dept Mol Biol & Lab Sci EpiGen Lorenskog Norway Univ Oslo Norwegian Ctr HPH Network Inst Clin Med Oslo Norway Oslo Univ Hosp Radiumhosp Inst Canc Res Dept Genet Oslo Norway Canc Registry Norway Inst Populat Based Res Oslo Norway
Tumor size, as indicated by the T-category, is known as a strong prognostic indicator for breast cancer. It is common practice to distinguish the T1 and T2 groups at a tumor size of 2.0 cm. We investigated the 2.0-cm ... 详细信息
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