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检索条件"主题词=microarray expression"
20 条 记 录,以下是11-20 订阅
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Human microRNA target identification by RRSM
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JOURNAL OF THEORETICAL BIOLOGY 2011年 第1期286卷 79-84页
作者: Hsieh, Wan J. Wang, Hsiuying Natl Chiao Tung Univ Inst Stat Hsinchu Taiwan
MicroRNAs (miRNAs) are small endogenously expressed non-coding RNAs that regulate target messenger RNAs in various biological processes. In recent years, there have been many studies concentrated on the discovery of n... 详细信息
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Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data
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GENES AND IMMUNITY 2005年 第4期6卷 319-331页
作者: Abbas, AR Baldwin, D Ma, Y Ouyang, W Gurney, A Martin, F Fong, S Campagne, MV Godowski, P Williams, PM Chan, AC Clark, HF Genentech Inc Dept Bioinformat San Francisco CA 94080 USA Genentech Inc Dept Immunol San Francisco CA 94080 USA Genentech Inc Dept Mol Biol San Francisco CA 94080 USA
Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. We have compiled a compendium of microarray expression data for virtually all human genes from six key i... 详细信息
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Gene signatures reflect the marked heterogeneity of tissue-resident macrophages
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IMMUNOLOGY AND CELL BIOLOGY 2008年 第3期86卷 246-254页
作者: Gorgani, Nick N. Ma, Yan Clark, Hilary F. Genentech Inc Dept Bioinformat San Francisco CA 94080 USA Genentech Inc Dept Immunol San Francisco CA 94080 USA
Tissue-resident macrophages play an important role in defense against pathogens and perform key functions in organ homeostasis, innate and adaptive immunity. Tissue macrophages originate from blood monocytes that infi... 详细信息
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A protein interaction network associated with asthma
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JOURNAL OF THEORETICAL BIOLOGY 2008年 第4期252卷 722-731页
作者: Hwang, Sohyun Son, Seung-Woo Kim, Sang Cheol Kim, Young Joo Jeong, Hawoong Lee, Doheon Korea Adv Inst Sci & Technol Dept Bio & Brain Engn Taejon South Korea Korea Adv Inst Sci & Technol Inst BioCentury Dept Phys Taejon South Korea KRIBB Korean BioInformat Ctr Taejon South Korea Yonsei Univ Dept Appl Stat Seoul 120749 South Korea
Identifying candidate genes related to complex diseases or traits and mapping their relationships require a system-level analysis at a cellular scale. The objective of the present study is to systematically analyze th... 详细信息
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Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors
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CANCER TREATMENT REVIEWS 2008年 第3期34卷 206-222页
作者: Duenas-Gonzalez, Alfonso Candelaria, Myrna Perez-Plascencia, Carlos Perez-Cardenas, Enrique de la Cruz-Hernandez, Erick Herrera, Luis A. Univ Nacl Autonoma Mexico Inst Invest Biomed Unidad Invest Biomed Canc INCan Mexico City 04510 DF Mexico Inst Nacl Cancerol Div Invest Clin Mexico City DF Mexico
Among many anticancer drugs collectively named "targeted or molecular therapies" epigenetic drugs are clearly promising. Differently from other agents targeting a single gene product, epigenetic drugs have c... 详细信息
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Modeling nonlinearity in dilution design microarray data
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BIOINFORMATICS 2007年 第11期23卷 1339-1347页
作者: Zheng, Xiuwen Huang, Hung-Chung Li, Wenyuan Liu, Peng Li, Quan-Zhen Liu, Ying Univ Texas Dept Math Sci Richardson TX 75083 USA Univ Texas Dept Comp Sci Richardson TX 75083 USA Univ Texas Dept Mol & Cell Biol Richardson TX 75083 USA Iowa State Univ Dept Stat Ames IA 50011 USA Univ Texas Med Ctr Microarray Core Facil Dallas TX 75390 USA
Motivation: Dilution design (Mixed tissue RNA) has been utilized by some researchers to evaluate and assess the performance of multiple microarray platforms. Current microarray data analysis approaches assume that the... 详细信息
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Kernel hierarchical gene clustering from microarray expression data
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BIOINFORMATICS 2003年 第16期19卷 2097-2104页
作者: Qin, J Lewis, DP Noble, WS Columbia Univ Columbia Genome Ctr New York NY 10032 USA Columbia Univ Dept Comp Sci New York NY 10027 USA Univ Washington Dept Genome Sci Seattle WA 98195 USA
Motivation: Unsupervised analysis of microarray gene expression data attempts to find biologically significant patterns within a given collection of expression measurements. For example, hierarchical clustering can be... 详细信息
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Utilizing logical relationships in genomic data to decipher cellular processes
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FEBS JOURNAL 2005年 第20期272卷 5110-5118页
作者: Bowers, PM O'Connor, BD Cokus, SJ Sprinzak, E Yeates, TO Eisenberg, D Univ Calif Los Angeles Howard Hughes Med Inst Los Angeles CA 90095 USA Univ Calif Los Angeles Inst Genom & Proteom Los Angeles CA 90095 USA Univ Calif Los Angeles Dept Chem & Biochem Los Angeles CA 90095 USA Univ Calif Los Angeles Dept Math Los Angeles CA 90095 USA
The wealth of available genomic data has spawned a corresponding interest in computational methods that can impart biological meaning and context to these experiments. Traditional computational methods have drawn rela... 详细信息
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Analysis of microarray expression data
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Genome Biology 2000年 第1期1卷 1-4页
作者: Paul Kellam
Detailed descriptions of the design and information content of EBI's database ArrayExpress, which is currently under development but aims to be a public repository of gene expression data, are the main feature of ... 详细信息
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Autocrine loops
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Genome Biology 2001年 第1期2.0卷 1-2页
作者: Weitzman, Jonathan B.
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