Biochemical techniques have given to biology experimental tools for sequencing genome fragments. These fragments were of a short length/spl minus/often corresponding to a single gene/spl minus/until the development of...
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Biochemical techniques have given to biology experimental tools for sequencing genome fragments. These fragments were of a short length/spl minus/often corresponding to a single gene/spl minus/until the development of extremely fast sequencing methods. Now, large sequencing projects have been started, leading to the availability of huge continuous fragments (300 kBytes for yeast chromosome III). Besides the problem of storing and representing such an amount of data, there is also the fact that the internal organization of these large fragments is often completely unknown. Consecutively, in the near future, the data and knowledge bases dedicated to molecular biology will be most certainly associated with sequence analysis systems in a way to help study the unannotated fragments. We present an example of such association between two biological object-oriented knowledge bases/spl minus/ColiGene (for Escherichia coli) and MultiMap (for mammalian genomes)/spl minus/and two sets of methods that are able to communicate with them: Digit (Dynamics and Interactive Graphical Integrated Tools) and Misa (Modules for Integrated Sequence Analysis). Then we show how it is possible to formalize the methods under an object-oriented knowledge representation model for tasks.< >
Medical data consist of many kinds of data from different resources, such as natural language data, sound data from physical examinations, numerical data from laboratory examinations, time-series data from monitoring ...
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Medical data consist of many kinds of data from different resources, such as natural language data, sound data from physical examinations, numerical data from laboratory examinations, time-series data from monitoring systems, and medical images (e.g. X-ray, Computer Tomography, and Magnetic Resonance Image). Therefore it has been pointed out that medical databases should be implemented as multidatabases. However, there have been few systems which integrate these data into multidatabases. In this paper, we report a system called COBRA (Computer-Operated Birth-defect Recognition Aid), which supports diagnosis and information retrieval of congenital malformation diseases and which also integrates natural language data, sound data, numerical data, and medical images into multidatabases on syndrome of congenital malformation. The results show that object-oriented scheme makes it easy to implement and integrate these knowledge-databases in COBRA, which suggests that these clinical databases should be implemented as object-oriented databases.
Presents a methodology for managing information resources by permitting aggregations of mixed-media documents to be interactively defined, shared, and managed using relational database management technology in concert...
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Presents a methodology for managing information resources by permitting aggregations of mixed-media documents to be interactively defined, shared, and managed using relational database management technology in concert with an extended object-oriented data model. This hybrid approach, based on a polymorphic object model (POM), allows the definition and instantiation of new types of compound documents without requiring modifications to be made to the underlying database schema. Existing documents and results from database queries are dynamically organized into individually meaningful categories as objects using a predicate-based mechanism. Furthermore, the authors have developed a prototype document management system based on the POM. Analysis indicates that gains in flexibility are traded for slightly increased amounts of meta-data management overhead and document retrieval latencies when compared to conventional DBMS technology.< >
Integration of autonomous object-oriented systems requires the integration of object structure and object behaviour. Research in federated information systems has so far mainly addressed integration of object structur...
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Integration of autonomous object-oriented systems requires the integration of object structure and object behaviour. Research in federated information systems has so far mainly addressed integration of object structure. The integration of object behaviour carries with it the promise to finally move integration tools beyond the state of the art at which they have (roughyl) existed for the better part of a decade, and we are embarked on a project that examines this problem in terms of object life cycles. The topic is also increasing in actuality since it also applies to the integration of business processes, which is typically required when companies merge or enter into consumer-producer relationships, and results can be expected to naturally extend to the arena of web services. Ultimately, the goal will be to define consistency criteria for behaviour integration and apply them in integration tools that guide the definition of global behavioural views upon autonomous object-oriented systems.
Meeting memory features are poorly integrated into current group support systems (GSS). This paper discusses how to introduce meeting memory functionality into a GSS. The author first introduces the benefits of a good...
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Meeting memory features are poorly integrated into current group support systems (GSS). This paper discusses how to introduce meeting memory functionality into a GSS. The author first introduces the benefits of a good meeting and organizational memory to an organization. Then, challenges such as storing semantically rich output, building up the meeting memory during the meeting with a minimum of additional effort and integrating meeting memory into organizational memory, and privacy protection are discussed. Finally, using the group-objectobject-oriented model of a GSS, the author shows how meeting memory functionality can be implemented in a GSS.< >
XML (eXtended Markup Language) has been widely used as the universal format for publishing and exchanging data in World Wide Web, due to its capability to support flexible representations of data. For that, the import...
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ISBN:
(纸本)9781467356107
XML (eXtended Markup Language) has been widely used as the universal format for publishing and exchanging data in World Wide Web, due to its capability to support flexible representations of data. For that, the importance of transforming other data sources, such as objectoriented Data Base (OODB) and Relational Database to XML, has increased. The goal of this paper is to develop an efficient method to transform OODB to XML that can be used by wide range of endusers who don't have to be specialists. Although the paper presents no novel approach, but it is mainly concerned with developing rule based methodology to convert OODB schema to XML schema.
The objective of this paper is to present the first results concerning the mapping and implementation of the Fuzzy Semantic Model (FSM) as a Fuzzy object-Relational database Model (FuzzORM). This solution permits to t...
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ISBN:
(纸本)9781467374293
The objective of this paper is to present the first results concerning the mapping and implementation of the Fuzzy Semantic Model (FSM) as a Fuzzy object-Relational database Model (FuzzORM). This solution permits to take advantages of both relational and object-oriented databases. The object-relational database management system PostgreSQL has been used for the implementation of the FuzzORM.
We present on-going research concerning an objectoriented associative memory. It is a massively parallel architecture, fully programmable and configurable, composed of VLSI circuits. It is well adapted to genome data...
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We present on-going research concerning an objectoriented associative memory. It is a massively parallel architecture, fully programmable and configurable, composed of VLSI circuits. It is well adapted to genome data processing. DNA and proteins sequences alignment is a very important application in biology research. Standard sequences alignment usually entails software implementation with disastrous execution time (typically one year). A parallel implementation can solve such a problem. Rapid-2 will be able to execute and accelerate genome tasks. We programmed and simulated several variants of the Needleman and Wunsch algorithm (1970) with progressive complexity (gaps, Dayhoff mutation matrix). Execution time evaluations of all these methods are presented. We consider that Rapid-2 could improve software implementation of a factor 100.< >
This paper briefly describes the new results of the Cave Project. Cave Project is a research initiative aiming to make possible a user-transparent distribution of CAD resources over the World Wide Web. Early results o...
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ISBN:
(纸本)9780769508436
This paper briefly describes the new results of the Cave Project. Cave Project is a research initiative aiming to make possible a user-transparent distribution of CAD resources over the World Wide Web. Early results on developing a web based interface for integrated circuits design tools were presented in the late 1990s. By the year 2000, the research focus has been on evolving the tool-tool integration architecture to provide better design flow modeling using object-oriented design representation.
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