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检索条件"主题词=predictive algorithm"
104 条 记 录,以下是51-60 订阅
排序:
Classifying Variants of CDKN2A Using Computational and Laboratory Studies
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HUMAN MUTATION 2011年 第8期32卷 900-911页
作者: Miller, Peter J. Duraisamy, Sekhar Newell, Joan A. Chan, Philip A. Tie, Mark M. Rogers, Amy E. Ankuda, Claire K. von Walstrom, Genevieve M. Bond, Jeffrey P. Greenblatt, Marc S. Univ Vermont Coll Med Hematol Oncol Unit Dept Med Burlington VT 05405 USA Univ Vermont Coll Med Vermont Canc Ctr Burlington VT 05405 USA
Variants in the CDKN2A tumor suppressor are associated with Familial Melanoma (FM), although for many variants the linkage is weak. The effects of missense variants on protein function and pathogenicity are often uncl... 详细信息
来源: 评论
A non-invasive algorithm accurately predicts advanced fibrosis in hepatitis C:: A comparison using histology with internal-external validation
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JOURNAL OF HEPATOLOGY 2008年 第4期49卷 564-571页
作者: Paggi, Silvia Colli, Agostino Fraquelli, Mirella Vigano, Mauro Del Poggio, Paolo Facciotto, Corinna Colombo, Massimo Ronchi, Guido Conte, Dario Univ Milan Div Gastroenterol 2 Fdn IRCCS Policlin Milan Italy A Manzoni Hosp Dept Internal Med Lecce Italy Univ Milan Div Gastroenterol 1 Fdn IRCCS Policlin AM & A Migliaracca Ctr Liver Dis Milan Italy Treviglio Hosp Hepatol Unit Treviglio Italy
Background/Aims: Biochemical tests and ultrasonography (US) are useful in the non-invasive assessment of liver fibrosis in patients with chronic hepatitis C (CH-C);however histology remains the reference standard. Thi... 详细信息
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LIMITED PROTEOLYSIS OF NATIVE PROTEINS - THE INTERACTION BETWEEN AVIDIN AND PROTEINASE-K
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PROTEIN SCIENCE 1995年 第7期4卷 1337-1345页
作者: ELLISON, D HINTON, J HUBBARD, SJ BEYNON, RJ UNIV MANCHESTER INST SCI & TECHNOLDEPT BIOCHEM & APPL MOLEC BIOLMANCHESTER M60 1QDLANCSENGLAND ZENECA BIOPROD BILLINGHAM TS23 1LBCLEVELANDENGLAND EUROPEAN MOLEC BIOL LAB D-69012 HEIDELBERGGERMANY
Avidin is a tetramer of 16-kDa subunits that have a high affinity for biotin. Proteolysis of native apoavidin by proteinase K results in a limited attack at the loop between beta-strands 3 and 4, involving amino acids... 详细信息
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Predicting first-trimester outcome of embryos with cardiac activity in women with recurrent spontaneous abortion
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JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 2020年 第6期48卷 300060520911829-300060520911829页
作者: Li, Huixian Qin, Shuang Xiao, Fanfan Li, Yuhong Gao, Yunhe Zhang, Jiexin Xiao, Qing Sun Yat Sen Univ Affiliated Hosp 8 3025 ShenNan Rd Shenzhen 518033 Guangdong Peoples R China Guangzhou Med Univ Inst Pediat Guangzhou Women & Childrens Med Ctr Guangzhou Guangdong Peoples R China Guangzhou Med Univ Guangzhou Women & Childrens Med Ctr Dept Reprod & Immunol Gynecol Guangzhou Guangdong Peoples R China Guangzhou Med Univ Dept Gynecol Outpatient Guangzhou Women & Childrens Med Ctr Guangzhou Guangdong Peoples R China
Objective This study was performed to evaluate the capability of routine clinical indicators to predict the early outcome of embryos with cardiac activity in women with recurrent spontaneous abortion (RSA). Methods A ... 详细信息
来源: 评论
Systematic review identifies the design and methodological conduct of studies on machine learning-based prediction models
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JOURNAL OF CLINICAL EPIDEMIOLOGY 2023年 154卷 8-22页
作者: Navarro, Constanza L. Andaur Damen, Johanna A. A. van Smeden, Maarten Takada, Toshihiko Nijman, Steven W. J. Dhiman, Paula Ma, Jie Collins, Gary S. Bajpai, Ram Riley, Richard D. Moons, Karel G. M. Hooft, Lotty Univ Utrecht Univ Med Ctr Utrecht Julius Ctr Hlth Sci & Primary Care Utrecht Netherlands Univ Utrecht Univ Med Ctr Utrecht Cochrane Netherlands Utrecht Netherlands Univ Oxford Ctr Stat Med Nuffield Dept Orthopaed Rheumatol & Musculoskeleta Oxford England Oxford Univ Hosp NHS Fdn Trust NIHR Oxford Biomed Res Ctr Oxford England Keele Univ Ctr Prognosis Res Sch Med Keele England Julius Ctr Hlth Sci & Primary Care Univ Weg 100POB 8550 NL-3508 GA Utrecht Netherlands
Background and Objectives: We sought to summarize the study design, modelling strategies, and performance measures reported in studies on clinical prediction models developed using machine learning ***: We search PubM... 详细信息
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Bile Is a Selective Elevator for Mucosal Mechanics and Transport
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MOLECULAR PHARMACEUTICS 2023年 第12期20卷 6151-6161页
作者: Hanio, Simon Mollmert, Stephanie Mockel, Conrad Choudhury, Susobhan Hopfel, Andreas I. Zorn, Theresa Endres, Sebastian Schlauersbach, Jonas Scheller, Lena Kessler, Christoph Scherf-Clavel, Oliver Bellstedt, Peter Schubert, Ulrich S. Poppler, Ann-Christin Heinze, Katrin G. Guck, Jochen Meinel, Lorenz Univ Wurzburg Inst Pharm & Food Chem D-97074 Wurzburg Germany Max Planck Inst Sci Light D-91058 Erlangen Germany Max Planck Zentrum Phys & Med D-91058 Erlangen Germany Univ Wurzburg Rudolf Virchow Ctr Integrat & Translat Bioimaging D-97080 Wurzburg Germany Univ Wurzburg Inst Organ Chem D-97074 Wurzburg Germany Univ Jena Inst Organ & Macromol Chem D-07743 Jena Germany Univ Zurich Inst Clin Chem CH-8091 Zurich Switzerland Friedrich Schiller Univ Jena Jena Ctr Soft Matter JCSM D-07743 Jena Germany Helmholtz Inst RNA Based Infect Res HIRI Wurzburg 97080 Germany
Mucus mechanically protects the intestinal epithelium and impacts the absorption of drugs, with a largely unknown role for bile. We explored the impacts of bile on mucosal biomechanics and drug transport within mucus.... 详细信息
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Chronic obstructive pulmonary disease and coronary disease: COPDCoRi, a simple and effective algorithm for predicting the risk of coronary artery disease in COPD patients
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RESPIRATORY MEDICINE 2015年 第8期109卷 1019-1025页
作者: Cazzola, Mario Calzetta, Luigino Matera, Maria Gabriella Muscoli, Saverio Rogliani, Paola Romeo, Francesco Univ Roma Tor Vergata Dept Syst Med Rome Italy Univ Naples 2 Dept Expt Med Naples Italy
Background: Chronic obstructive pulmonary disease (COPD) is often associated with cardiovascular artery disease (CAD), representing a potential and independent risk factor for cardiovascular morbidity. Therefore, the ... 详细信息
来源: 评论
Predicting worsening heart failure hospitalizations in patients with implantable cardioverter defibrillators: is it all about alerts? A pooled analysis of nine trials
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EUROPACE 2024年 第2期26卷 euae032页
作者: Botto, Giovanni Luca Sinagra, Gianfranco Bulava, Alan Gargaro, Alessio Timmel, Tobias Giacopelli, Daniele D'Onofrio, Antonio Guedon-Moreau, Laurence ASST Rhodense UO Electrophysiol Viale Carlo Forlanini 95 I-20024 Garbagnate Milanese MI Italy ASUGI Cattinara Hosp Cardiothoracovasc Dept Trieste Italy Univ Trieste Trieste Italy Univ South Bohemia Ceske Budejovice Ceske Budejovice Hosp Fac Hlth & Social Sci Ceske Budejovice Czech Republic Biotronik Italia SPA Clin Unit Cologno Monzese MI Italy Biotron SE & Co KG Ctr Clin Res Berlin Germany Monaldi Hosp Unita Operativa Elettrofisiol Studio & Terapia Ari Naples Italy Univ Lille Lille Univ Hosp Ctr CHU Lille Lille Hauts De France France
Aims To predict worsening heart failure hospitalizations (WHFHs) in patients with implantable defibrillators and remote monitoring, the HeartInsight algorithm (Biotronik, Berlin, Germany) calculates a heart failure (H... 详细信息
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Long-term effectiveness of the combined minute ventilation and patient activity sensors as predictor of heart failure events in patients treated with cardiac resynchronization therapy: Results of the Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT device Trial (CLEPSYDRA) study
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EUROPEAN JOURNAL OF HEART FAILURE 2014年 第6期16卷 663-670页
作者: Auricchio, Angelo Gold, Michael R. Brugada, Josep Noelker, G. Arunasalam, Siva Leclercq, Christophe Defaye, Pascal Calo, Leonardo Baumann, Oliver Leyva, Francisco Fdn Cardioctr Ticino Div Cardiol CH-6900 Lugano Switzerland Med Univ S Carolina Charleston SC USA Hosp Clin Barcelona Thorax Inst Barcelona Spain Herz & Diabet Zentrum Nordrhein Westfalen Bad Oeynhausen Germany Desert Valley Hosp Victorville CA USA Univ Hosp Dept Cardiol Rennes France Univ Hosp Dept Cardiol Grenoble France Policlin Casilino Div Cardiol Rome Italy Sorin CRM SAS Clamart France Univ Birmingham Ctr Cardiovasc Sci Birmingham W Midlands England
Aims Monitoring early signs of clinical deterioration could allow physicians to adjust medical treatment for patients at risk of acute heart failure decompensation. To date, several strategies using different surrogat... 详细信息
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PHARMACOKINETICS AND DOSAGE ADJUSTMENT OF ANTIBIOTICS DURING CONTINUOUS EXTRACORPOREAL LUNG ASSISTANCE AND HEMOFILTRATION
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ARTIFICIAL ORGANS 1992年 第5期16卷 457-460页
作者: KROH, UF HOLL, T FEUSSNER, KD UNIV MARBURG DEPT ANESTHESIOL & INTENS THERAPYW-3550 MARBURGGERMANY
Fifty-eight patients undergoing continuous volume-controlled hemofiltration (CVHF) and extracorporeal lung assistance (ECLA) received drug therapy determined by use of a new predictive algorithm in a validation study.... 详细信息
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