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Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data

BMC MEDICAL RESEARCH METHODOLOGY 2009年第1期9卷 1-12页

作者： Wallace, Byron C. Schmid, Christopher H. Lau, Joseph Trikalinos, Thomas A. Tufts Med Ctr Inst Clin Res & Hlth Policy Studies Ctr Clin Evidence Synth Boston MA 02111 USA Tufts Univ Dept Comp Sci Medford MA 02155 USA Tufts Med Ctr Biostat Res Ctr Inst Clin Res & Hlth Policy Studies Boston MA 02111 USA

Background: Meta-analysis is increasingly used as a key source of evidence synthesis to inform clinical practice. The theory and statistical foundations of meta-analysis continually evolve, providing solutions to many new and challenging problems. In practice, most meta-analyses are performed in general statistical packages or dedicated meta-analysis programs. Results: Herein, we introduce Meta-Analyst, a novel, powerful, intuitive, and free meta-analysis program for the meta-analysis of a variety of problems. Meta-Analyst is implemented in C# atop of the Microsoft. NET framework, and features a graphical user interface. The software performs several meta-analysis and meta-regression models for binary and continuous outcomes, as well as analyses for diagnostic and prognostic test studies in the frequentist and Bayesian frameworks. Moreover, Meta-Analyst includes a flexible tool to edit and customize generated meta-analysis graphs (e.g., forest plots) and provides output in many formats (images, Adobe PDF, Microsoft Word-ready RTF). The software architecture employed allows for rapid changes to be made to either the Graphical User Interface (GUI) or to the analytic modules. We verified the numerical precision of Meta-Analyst by comparing its output with that from standard meta-analysis routines in Stata over a large database of 11,803 meta-analyses of binary outcome data, and 6,881 meta-analyses of continuous outcome data from the Cochrane Library of Systematic Reviews. Results from analyses of diagnostic and prognostic test studies have been verified in a limited number of meta-analyses versus MetaDisc and MetaTest. Bayesian statistical analyses use the OpenBUGS calculation engine (and are thus as accurate as the standalone OpenBUGS software). Conclusion: We have developed and validated a new program for conducting meta-analyses that combines the advantages of existing software for this task.

关键词： Forest Plot Graphical Output string variable Summary Effect Size Intuitive Graphical User Interface

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Tektronix :: 49Xx :: 070-2380-01 4907Oper Feb79

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2016年

Tektronix :: 49Xx :: 070-2380-01 4907Oper Feb79 by published by

关键词： 4907oper call command command descriptions device device address disc feb feb79 file file manager file status files flexible disc graphic system logical file manager rev storage structure string string variable syntax form tektronix

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Ge :: Marki Timesharing :: 802207A Time-Sharingservicebasiclanguageextensionsreferencemanual Feb1968

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2016年

Ge :: Marki Timesharing :: 802207A Time-Sharingservicebasiclanguageextensionsreferencemanual Feb1968 by published by

关键词： 802207a basic basic language data data file error message extensions feb1968 file file designator files hilbert matrix language extensions marki mat mat print mat read matrix print print statement program statement string variable timesharing time-sharingservicebasiclanguageextensionsreferencemanual

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Tektronix :: 404X :: 070-3917-01 4041 System Controller Programmers Reference Dec1985

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2016年

Tektronix :: 404X :: 070-3917-01 4041 System Controller Programmers Reference Dec1985 by published by

关键词： controller data dec1985 device error floating point front panel function input interface port logical unit numeric print program program segment programmers reference set driver statement statement syntax stream spec string string variable system console

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Apple :: Apple I :: Applei Basicman

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2016年

Apple :: Apple I :: Applei Basicman by published by

关键词： apple apple basic applei array basic basic instructions basic program basicman destination string enter basic err error message execution expr expr expr print program program execution string string variable variable variable letter variables

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Sri :: Arc :: Nls Programmers Guide Sep79

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2016年

Sri :: Arc :: Nls Programmers Guide Sep79 by published by

关键词： address analyzer character position content content analyzer current character guide lio procedure program programmers scan direction sep79 sequence generator statement string string variable text text pointer text pointers user user programs userguidest progr

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Sri :: Arc :: Nls Programmers Guide Dec75

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2016年

Sri :: Arc :: Nls Programmers Guide Dec75 by published by

关键词： analyzer analyzer programs arc character position command word content content analyzer dec dec75 guide guide arc nls procedure program programmers sequence generator statement string string variable text pointer text pointers user user programs

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Discover Your Vic-20 (1983)(Birkhauser)

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2016年

[Auto Generated] Preface 1 Using the VIC Keyboard 1 2 Introduction to BASIC Programming 7 3 Bookkeeping in BASIC 11 4 The Basics of Editing 15 5 Printing with Color 19 6 Color and the POKE Command 23 7 Loops in Loops in Loops... 29 8 Music 1 35 9 Number Theory 1 41 10 Music 2 47 11 Microsurgery 53 12 Game Making 59 13 Moving Color 65 14 Number Theory 2 67 15 Advanced Color 73 16 User Defined Characters 79 Discover Your VIC-20 A Beginner's Guide to 1 Using the VIC Keyboard Like all computers, you

关键词： (1983)(birkhauser) bug color cursor direct mode discover goto loop memory map poke poke command print print names program quote mode reverse field screen screen character space bar string variable vic keyboard vic-20

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Dec :: Pdp10 :: Tops10 :: Dec-10-Lalma-A-D Algol Programmers Reference Ver 3B Jul74

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2016年

[Auto Generated] CHAPTER 1 INTRODUCTION 1.1 General 1-1 1.2 D ECsystem-1 0 ALGOL 1-1 1.3 The ALGOL Compiler 1-2 1.3.1 Compiler Extensions 1-2 1 .3.2 Compil er Restrictions 1-3 1.4 The ALGOL Operating Environment 1-3 1.5 Terminology 1-3 CHAPTER 2 PROGRAM STRUCTURE 2.1 Basic Symbols 2-1 2.2 Compound Symbol s 2-2 2.3 Delimiter Words 2-2 2.4 Use of Spacing and Commentary 2-4 CHAPTER 3 IDENTIFIERS AND DECLARATIONS 3.1 Identifi ers 3-1 3.2 Scalar Declarations 3-2 CHAPTER 4 CONSTANTS 4.1 Numeric Consta

关键词： algol algol programs array boolean byte byte string byte strings conditional statements dec-10-lalma-a-d device formal parameter integer jul74 long real pdp10 procedure programmers real real constants real procedure reference string string variable string variables user

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The Last Word on the Ti-99/4A

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2016年

作者： linda m schreiber

The Last Word on the Ti-99/4A by Schreiber, Linda M; Schreiber, Allen R; published by Blue Ridge Summit, Pa. : Tab Books

关键词： basic (computer program language) call char call clear call key character character set clear screen command computer display enter key key listing program rem listing screen string array string variable tab books ti 99 4a (computer) ti-99 4a variable

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