Purpose Blood pressure is an important vital signs of the *** disease caused by the abnormal regulation of blood pressure especially hypertension,its incidence rate is very *** kinds of abnormal blood pressure always ...
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Purpose Blood pressure is an important vital signs of the *** disease caused by the abnormal regulation of blood pressure especially hypertension,its incidence rate is very *** kinds of abnormal blood pressure always occurred during the *** of blood pressure during sleep is still *** evidence has shown that hippocampus has an important role in the regulation of blood pressure during *** some contradiction is always *** purpose of this project that would like to further explore the specific regulatory mechanisms of the hippocampal network in the state of *** about 30 urethane-anesthetized rats was adopted as a simple sleep model in this *** network electrical activity and femoral artery blood pressure with EKG are all recorded *** all the data will be analyzed offline to explore the cellular mechanism of cardiovascular regulation in sleep ***:1)Cyclic alternation pattern of hippocampal fieldpotential has been *** pattern mainly contains two kinds of oscillation inclueds theta oscillation and slow oscillation(n=24,24/30=80%).This characteristic is very similar to the electroencephalogram in *** pressure and heart rate are also cyclically changed in a narrow band at the same *** femoral artery blood pressure in the theta phase was lower than in the slow oscillation phase,the value is about 13.64±3.31mm *** the heart rate in the theta phase was higher than in the slow oscillation phase,the value is about 5.14±0.9 bpm.2)Two kinds of theta related cells in the hippocampal network has been ***-on cell unit discharge was increased when theta oscillation occurred,(n=15).At the same time,the heart rate was also *** the slow oscillation and spindle occurred,the unit discharge and heart rate were also *** wave length is proportional to interspike interval of theta-on cell unit discharge(r=0.902,p<0.05).And theta-on
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