本研究采用前瞻性、随机、对照的临床研究方法,对92例CKD 3~4期诊断为脾肾气虚、湿浊瘀阻证的患者进行观察。随机分为“西医一体化治疗基础方案”对照组和“西医一体化治疗基础疗法结合热敏灸疗法”治疗组,每组46例患者,治疗周期为12周。对照组患者予以西医一体化治疗方案,治疗组患者在对照组治疗方案的基础上予以双侧膈俞穴、脾俞穴、三焦俞穴、肾俞穴和命门穴热敏灸治疗。治疗前后记录两组患者一般情况及热敏灸气感维持时间,并检测患者Scr、Cysc、eGFR、BUN、UA、IL-6、TNF-α、NLR等指标,评价两组临床疗效和中医证候疗效。A prospective, randomized, controlled clinical study was conducted to observe 92 patients diagnosed with spleen kidney qi deficiency, dampness turbidity and blood stasis syndrome in CKD 3~4 stage. They were randomly divided into a control group of “Western medicine integrated treatment basic plan” and a treatment group of “Western medicine integrated treatment basic therapy combined with thermal moxibustion therapy”, with 46 patients in each group and a treatment period of 12 weeks. The control group patients were treated with a Western medicine integrated treatment plan, while the treatment group patients were treated with bilateral thermal moxibustion on the basis of the control group treatment plan at the points of Geshu, Piyu, Sanjiao Yu, Shenshu, and Mingmen. Before and after treatment, the general condition of two groups of patients and the duration of thermal moxibustion gas sensation were recorded, and measure indicators such as Scr, Cysc, eGFR, BUN, UA, IL-6, TNF-α, and NLR were detected to evaluate the clinical efficacy and traditional Chinese medicine syndrome efficacy of the two groups.
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