背景与目的 正确的诊断对肺癌疑似患者是至关重要的。根据肿瘤组织摄取18 F FDG的能力远大于正常组织的原理,本研究探讨了双探头符合线路SPECT/CT在肺癌诊断中的临床应用价值。方法 对61例肺部肿块患者进行18F FDG SPECT/CT检查,对良...
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背景与目的 正确的诊断对肺癌疑似患者是至关重要的。根据肿瘤组织摄取18 F FDG的能力远大于正常组织的原理,本研究探讨了双探头符合线路SPECT/CT在肺癌诊断中的临床应用价值。方法 对61例肺部肿块患者进行18F FDG SPECT/CT检查,对良恶性肿块的摄取比值R进行比较,并与CT检查和病理检查结果进行比较。结果 以摄取比值R≥2 为标准,18 F FDG SPECT/CT对肺癌诊断的敏感性为82%,特异度为87%,准确率为84%。18 F FDG SPECT/CT对纵隔淋巴结转移的诊断与病理结果的符合率为81%,而CT诊断与病理结果的符合率为52%,二者有显著性差异(P<0.05)。结论 18 F FDG SPECT/CT对肺癌的诊断与鉴别诊断以及临床分期有重要的应用价值。
In the treatment of a peripheral nerve defect, the use of a tissue engineered artificial nerve may offer an alternative to a nerve autograft Three aspects of a tissue engineered artificial nerve were reviewed: Schwann...
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In the treatment of a peripheral nerve defect, the use of a tissue engineered artificial nerve may offer an alternative to a nerve autograft Three aspects of a tissue engineered artificial nerve were reviewed: Schwann cell culture, the construction of a three dimensional intrinsic framework for the seeding of Schwann cells, and the fabrication of a biodegradable and semipermeable nerve tube Schwann cell cultivation could be simplified using a serum free medium or in vivo degenerated nerve grafts To improve the attachment and alignment of Schwann cells on the three dimensional intrinsic framework, coating the biomaterials with extracellular matrices and application of a rotating culture system were accepted as promising techniques A few biodegradable and semipermeable nerve tubes made from polyglycolic acid, polylactic acid or collagen were available The dimensions and link of growth factors played a role during nerve regeneration? Until now, tissue engineered artificial nerves have been proved to be effective on supporting nerve regeneration However, the results were inferior to nerve autografts in the case of a long nerve defect The embryonic Schwann cell might be a source of cell due to their wide availability and poor antigenicity In addition, incorporation of growth factors into the intrinsic framework or nerve guides may promote the survival of transplanted Schwann cells and subsequently nerve regeneration The suitable biomaterials are yet to be investigated until an optimal result can be
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