Adenovirus vectors have become a very popular tool for gene transfer into mammalian cells. Traditionally, the construction of first generation adenovirus vectors was a time - consuming process, requiring 2 to 3 months...
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Adenovirus vectors have become a very popular tool for gene transfer into mammalian cells. Traditionally, the construction of first generation adenovirus vectors was a time - consuming process, requiring 2 to 3 months of intensive labor. The AdEasy system simplifies the production of such viruses. The adenovirus E3 region encodes products that counteract host defense mechanisms, which are not essential for viral replication in vitro, and therefore the E3 region was deleted in
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