本文根据1958年1月至1983年12月1175例资料完整的胃癌切除病例，按新分期法进行分析研究。结果：Ⅰ a 、Ⅰ b 、Ⅱ、Ⅲ a 、Ⅲ b 及Ⅳ期的5年生存率分别为100%、84%、65%、43%、25%及13%；同期内各亚组间的生存率亦十分接近，说明新分...
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本文根据1958年1月至1983年12月1175例资料完整的胃癌切除病例，按新分期法进行分析研究。结果：Ⅰ a 、Ⅰ b 、Ⅱ、Ⅲ a 、Ⅲ b 及Ⅳ期的5年生存率分别为100%、84%、65%、43%、25%及13%；同期内各亚组间的生存率亦十分接近，说明新分期法能准确反映分期与预后理应具备的一致性。相关系数r=-0.990，回归系数b=-0.1345，差异均有非常显著性（P<0.0005），进一步证实了上述结论。
ObjectiveTo investigate BCL 6 gene mutations in Chinese populations with B cell non Hodgkin's lymphoma Methods Polymerase chain reaction (PCR), denaturing gradient gel electrophoresis (DGGE) and direct D...
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ObjectiveTo investigate BCL 6 gene mutations in Chinese populations with B cell non Hodgkin's lymphoma Methods Polymerase chain reaction (PCR), denaturing gradient gel electrophoresis (DGGE) and direct DNA sequencing were used to identify mutations in the 5' noncoding region of the BCL 6 gene in a total of 40 cases of diffuse large cell lymphoma (DLCL) and follicular lymphoma (FL) Results Nine cases were found to have base substitutions The incidence of BCL 6 gene mutation and the frequency of single base changes were approximately 25 7% and (0 56-1 10)×10 2 /bp, respectively Conclusions The 5' regulatory region of the BCL 6 gene undergoes frequent somatic hypermutation during lymphomagenesis and the identification of BCL 6 gene hypermutations provides a molecular marker for confirmatory diagnosis of B NHL
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