The nervous system is a complex network with many types of neurons and numerous synaptic *** present knowledge on how neurons recognize specific targets and form such an intricate network is still *** Down syndrome ce...
详细信息
The nervous system is a complex network with many types of neurons and numerous synaptic *** present knowledge on how neurons recognize specific targets and form such an intricate network is still *** Down syndrome cell adhesion molecule （DSCAM） belongs to the immunoglobulin superfamily and contributes to defects in the central nervous system in Down syndrome *** plays important roles in neural development,including dendritic patterning and self-avoidance,axon guidance and branching,axon target recognition and synaptic ***,the functional mechanisms and the underlying signaling pathways are still largely *** the functions of DSCAM in neural development were *** research for better understanding DSCAM function and the relevance of DSCAM to human diseases was also discussed.
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