Objective To analyze the characteristics of hepatic metastasis of pure immature ovarian teratoma and explore its proper diagnosis and *** Eighteen cases of hepatic metastasis of pure immature ovarian teratoma were inc...
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Objective To analyze the characteristics of hepatic metastasis of pure immature ovarian teratoma and explore its proper diagnosis and *** Eighteen cases of hepatic metastasis of pure immature ovarian teratoma were included in this study. The clinical stage, operation, chemotherapy and histopathology of primary and secondary tumors as well as the data from long term follow-ups were analyzed retrospectively,Results All of the hepatic metastatic tumors were located on the surface of the liver. 61.1％ (11/18) of them were clinical stage Ⅲ and 44.4％ (8/18) were grade 1 at first operation. The hepatic metastatic rate was 16.7％ (3/18) in the standard adjuvant chemotherapy group but increased markedly to 31.2％ (15/48) in the irregular chemotherapy group. Auxiliary diagnostic methods could not indicate the correct results. The surgical resection rate of hepatic metastasis of pure immature ovarian teratoma was 94.4％ (17/18). There were less complications in the group with tumor diameter less than 15 cm. The follow-up time ranged from 3 to 205 months with a mean of 20.9 months. The 3-year-survival rate was 77.8％ (14/ 18), and mortality rate was 22.2％. The 5- and 10-year-survival rate was 55.6％ (10/18) and 38.9％ (7/18), respectively. The rate of loss in follow-up was 22.2％ (4/18) and 38.9％ (7/18), respectively, and one patient has survived for more than 17 *** The hepatic metastatic rate of pure immature ovarian teratoma could be decreased using standard adjuvant chemotherapy. Suitable surgical treatment could reduce complications and improve the prognosis for patients.
目的观察两种不同的正电子发射型计算机断层扫描(PET)显像对常规检查无法明确的肝脏占位的诊断价值。方法在489例临床诊断为肝脏占位的患者中,收集经各种常规检查无法定性,且有条件行两次 PET 检查的患者15例。所有患者均在手术前接受^(...
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目的观察两种不同的正电子发射型计算机断层扫描(PET)显像对常规检查无法明确的肝脏占位的诊断价值。方法在489例临床诊断为肝脏占位的患者中,收集经各种常规检查无法定性,且有条件行两次 PET 检查的患者15例。所有患者均在手术前接受^(11)C-乙酸盐-PET 和^(18)F-去氧葡萄糖(FDG)-PET 检查。结果病理证实恶性病变13例,良性病变2例。在13例恶性病变中,^(11)C-乙酸盐 PET 提示恶性10例,良性3例;^(18)F-FDG-PET 提示恶性9例,良性4例;在2例良性病变中,^(11)C-乙酸盐 PET 提示恶性和良性各1例;^(18)F-FDG-PET 提示恶性和良性也各1例。对于高中分化肝细胞肝癌,^(11)C-乙酸盐 PET 所显示的敏感性(100%)高于^(18)F-FDG-PET 的敏感性(20%);对于低中分化的肝细胞肝癌,^(18)F-FDG 的敏感性高。结论在常规检查不能明确肝占位性质时,有条件的情况下应用两种 PET 示踪剂能提高相关的诊断率,两种示踪剂联合应用还可提示肿瘤的分化程度,对于手术方式的选择有一定的指导意义。
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