Cancer is the second leading disease causing human ***-clinical in vivo studies are essential for translating in vitro laboratory research results into the ***,including the mouse and rat,have been widely used for pre...
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Cancer is the second leading disease causing human ***-clinical in vivo studies are essential for translating in vitro laboratory research results into the ***,including the mouse and rat,have been widely used for pre-clinical studies due to their small size,clear genetic backgrounds,rapid propagation,and mature transgenic ***,because rodents are evolutionarily distinct from humans,many pre-clinical research results using rodent models cannot be reproduced in the ***-human primates（NHPs） may be better animal models than rodents for human cancer research because NHPs and humans share greater similarity in regards to their genetic evolution,immune system,physiology and *** article reviews the latest progress of cancer research in NHPs by focusing on the carcinogenesis of different NHPs induced by chemical and biological ***,future research directions for the use of NHPs in cancer research are discussed.
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