肩部钙化性肌腱炎(RCCT)是由于钙化物质在关节周围的肌腱中沉积,刺激肌腱并导致其柔韧性下降及炎症反复发作的非创伤性肩部疾病。其确切的发病机制目前尚未完全明确。RCCT在中医学中属于“痹症”等范畴,中医对肩痹疼痛的研究历史悠久。目前,针对肩袖钙化性肌腱炎的治疗方法尚未形成统一的标准,中西医治疗各有其优势。鉴于本病具有自限性特点,保守治疗和微创治疗成为首选方案,对于那些经过保守治疗无效的RCCT患者,最终可能需要采取手术治疗。本文旨在探讨肩袖钙化性肌腱炎的中西医诊疗策略。Rotator cuff calcific tendonitis (RCCT) is a non-traumatic shoulder disease caused by the deposition of calcified substances in the tendons around the joint, which stimulates the tendons and leads to a decrease in flexibility and recurrent inflammation. The exact pathogenesis is currently not fully understood. RCCT belongs to the category of “bi syndrome” in traditional Chinese medicine, and the research history of shoulder bi pain in traditional Chinese medicine is long. At present, there is no unified standard for the treatment of calcified tendinitis of the rotator cuff, and both traditional Chinese and Western medicine have their own advantages in treatment. Given the self-limiting nature of this disease, conservative and minimally invasive treatments have become the preferred options. For RCCT patients who have failed conservative treatment, surgical intervention may ultimately be necessary. This article aims to explore the diagnosis and treatment strategies of calcified tendinitis of the rotator cuff using both traditional Chinese and Western medicine.
背景:干细胞具有促进神经再生、修复受损神经、抑制炎症反应和神经细胞凋亡的作用,为阿尔茨海默病治疗提供了一种全新的途径。目的:对2004-2023年国际发表的干细胞治疗阿尔茨海默病的文献进行文献计量学分析,揭示干细胞治疗阿尔茨海默病的研究热点和趋势。方法:以Web of Science核心合集数据库为来源,利用Excel、VOSviewer、Citespace软件对2004-01-01/2023-10-31发表的与干细胞和阿尔茨海默病相关的文献进行年发文量、国家、机构、期刊/共被引期刊、作者和关键词等的可视化分析。结果与结论:共纳入核心文献3521篇,年发文量逐年攀升;美国是发文最多的国家,哈佛医学院是最高产的机构,Maiese kenneth是发文量最多的作者,《International Journal of Molecular Sciences》在该领域发文量最多,《PLoS One》发表的文献被引次数最多;目前干细胞治疗阿尔茨海默病领域以病理生理机制和动物实验研究为侧重点,“神经发生”“氧化应激”“细胞外囊泡”“间充质干细胞”是该领域研究的趋势热点。干细胞治疗阿尔茨海默病具有广阔的前景,未来应加强机构和作者间的交流合作,深入探索干细胞治疗阿尔茨海默病的主要机制,解决临床可能遇到的免疫排斥、有效性及安全性等问题,进一步挖掘干细胞在阿尔茨海默病治疗中的潜力。
绝经前后全身皮肤发黄发黑在中医学中极为罕见,属“绝经前后诸证”范畴,中医药治疗具有标本同治的优势,文章总结了导师彭强丽主任医师治疗该病的临证经验,彭师认为该病多以绝经前后肾气衰退,肾水未能滋养肝木,肝失条达,气机郁滞化火,而致使脾胃失于健运为主要病因病机,临证需补肾、疏肝、健脾三脏同调,故治以丹栀逍遥散加减,并配以心理疏导,取得显著疗效。The yellow and black skin of the whole body before and after menopause is extremely rare in traditional Chinese medicine, which belongs to the category of “symptoms before and after menopause”. The treatment of traditional Chinese medicine has the advantage of the same treatment of specimens. The article summarized the clinical experience of the chief physician of the mentor Peng Qiangli in the treatment of this disease, Peng said that the disease is mostly caused by the kidney qi decline before and after menopause, the kidney “water” fails to nourish the liver “wood”, the liver function impairs, and the qi stagnation becomes “fire”. The spleen and stomach loss in health transport as the main cause of disease, clinical need to tonifying the kidney, soothing the liver, spleen three viscera homology, so the treatment to Danzhi Xiaoyao powder plus or less, and with psychological guidance, achieved significant effect.
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