作者：
郑仁垟朱月香陈经广北京分子科学国家实验室
分子动态与稳态结构国家重点实验室北京大学化学与分子工程学院北京 100871 Department of Chemical Engineering
Center for Catalytic Science and Technology(CCST)University of DelawareNewarkDE19716(USA) 北京分子科学国家实验室分子动态与稳态结构国家重点实验室北京大学化学与分子工程学院北京 100871 Department of Chemical EngineeringCenter for Catalytic Science and Technology(CCST)University of DelawareNewarkDE19716(USA)
L-Tyr-EMPO,a new EMPO analogue bearing an L-tyrosine methyl ether group,was first synthesized by *** radicals,including O-·2,·OH,·OR,and ·R,have been efficiently detected and characterized via *** ...
详细信息
L-Tyr-EMPO,a new EMPO analogue bearing an L-tyrosine methyl ether group,was first synthesized by *** radicals,including O-·2,·OH,·OR,and ·R,have been efficiently detected and characterized via *** half-life of the L-Tyr-EMPO superoxide adduct was estimated to be ca.6.5 *** importantly,the present study demonstrated a new synthetic strategy for covalent conjugation between cyclic-nitrone and amino group in peptides or proteins,by which the site-specifically spin trapping can be performed via antibody linked nitrone in the near ***,with the help of the covalent link,the targeting for the areas of interest in which the monitored radical species was sitespecially generated.
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