Background: The Tumor necrosis factor (TNF) is an established therapeutic target for rheumatoid arthritis and other autoimmune *** 5 TNF antagonists available on market now are all protein therapeutics.A major problem...
详细信息
Background: The Tumor necrosis factor (TNF) is an established therapeutic target for rheumatoid arthritis and other autoimmune *** 5 TNF antagonists available on market now are all protein therapeutics.A major problem limiting development of protein therapeutics is their sensitivity to proteases and delivery challenges.D-Peptides are highly resistant to natural proteases because of the stereospecificity.
H/ACA ribonucleoprotein particles (RNPs)(Figure 1(a)), the most complicated RNA pseudouridylases, use H/ACA guide RNA for substrate capture and four proteins (Cbf5, Nop10, Gar1 and L7Ae) for *** work [1] in our lab ha...
详细信息
H/ACA ribonucleoprotein particles (RNPs)(Figure 1(a)), the most complicated RNA pseudouridylases, use H/ACA guide RNA for substrate capture and four proteins (Cbf5, Nop10, Gar1 and L7Ae) for *** work [1] in our lab has shown that Gar1 accelerates the product release.
暂无评论