The aspartate receptor (Tar) in ***, a crucial component in the bacterial sensory systems that mediate chemotaxis, has been intensively studied for years[1].However the kinetics of Tar-ligand binding in vivo is still ...
The aspartate receptor (Tar) in ***, a crucial component in the bacterial sensory systems that mediate chemotaxis, has been intensively studied for years[1].However the kinetics of Tar-ligand binding in vivo is still not clear due to lack of labeling.
Intrinsically disordered proteins (IDPs) show little ordered structures under physiological *** 10% of proteins in various genomes have been predicted to be fully *** occur more often in disease related genes and may ...
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Intrinsically disordered proteins (IDPs) show little ordered structures under physiological *** 10% of proteins in various genomes have been predicted to be fully *** occur more often in disease related genes and may be used as potential drug design targets.
D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis[1], and can be allosterically inhibited by serine[2].
D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis[1], and can be allosterically inhibited by serine[2].
Background: The Tumor necrosis factor (TNF) is an established therapeutic target for rheumatoid arthritis and other autoimmune *** 5 TNF antagonists available on market now are all protein therapeutics.A major problem...
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Background: The Tumor necrosis factor (TNF) is an established therapeutic target for rheumatoid arthritis and other autoimmune *** 5 TNF antagonists available on market now are all protein therapeutics.A major problem limiting development of protein therapeutics is their sensitivity to proteases and delivery challenges.D-Peptides are highly resistant to natural proteases because of the stereospecificity.
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