目的:对住院缺血性脑卒中病例进行回顾性分析,探索深静脉血栓形成的高危因素,为缺血性脑卒中患者深静脉血栓的防治提供依据。方法:采用回顾性分析方法,从南方医科大学深圳医院电子病历系统随机选取2018年1月至2022年3月入住神经内科的缺血性脑卒中病例,共纳入完整样本298例。以发生深静脉血栓为结局指标,采用单因素和多因素二元Logistic回归分析形成深静脉血栓的独立危险因素。结果:298例缺血性脑卒中病人中有36例住院期间确诊为下肢深静脉血栓形成。单因素分析结果显示入院时NIHSS分值、出院时NIHSS分值、入院时ADL评分、出院时ADL评分、入院时吞咽功能评估分值、入院时MRS分值、出院时MRS分值、半胱氨酸、APTT、D二聚体、左上肢肌力、左下肢肌力、右上肢肌力、右下肢肌力共16项是缺血性脑卒中患者深静脉血栓形成的风险因素,差异有统计学意义(P Objective: A retrospective study was conducted to investigate the high-risk factors of the formation of deep venous thrombosis in patients with ischemic stroke so as to provide the basis for the prevention and treatment of deep vein thrombosis in patients with ischemic stroke. Methods: A total of 298 cases of ischemic stroke admitted to the Department of Neurology in Shenzhen Hospital of Southern Medical University from January 2018 to March 2022 were randomly selected by retrospective analysis. Patients’ information was collected from the information platform. With the occurrence of DVT as the outcome index, univariate and multivariate Logistic regression were used to analyze independent risk factors of DVT. Results: Among 298 patients with ischemic stroke, 36 were diagnosed with deep vein thrombosis in the lower limbs during their hospital stay. The results of univariate analysis showed NIHSS score at admission, NIHSS score at discharge, ADL score at admission, ADL score at discharge, swallowing function evaluation score at admission, and VTE (Caprini) after admission score, MRS score at admission, MRS score at discharge, cysteine result, left upper limb muscle strength, left lower limb muscle strength, right upper limb muscle strength and right lower limb muscle strength were the risk factors of deep venous thrombosis in patients with ischemic stroke, and the differences were statistically significant (P < 0.05);Multivariate Logistic analysis showed that NIHISS score at admission (OR = 1.033, P = 0.000), swallowing function assessment score at admission (OR = 3.988, P = 0.000), MRS score at
目的应用起立-行走计时测试(Timed Up and Go Test,TUGT)探究社区老年人群运动功能与情绪、认知、睡眠方面的相关性。方法横断面研究,2021年12月至2023年8月在中国北京市、天津市、浙江省、广东省、海南省随机招募60~90岁共739名受试者...
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目的应用起立-行走计时测试(Timed Up and Go Test,TUGT)探究社区老年人群运动功能与情绪、认知、睡眠方面的相关性。方法横断面研究,2021年12月至2023年8月在中国北京市、天津市、浙江省、广东省、海南省随机招募60~90岁共739名受试者,根据TUGT时间(t),将受试者分为运动正常组、运动轻度异常组和运动明显异常组。收集基本信息,并应用TUGT评估运动功能,中国修订的简易智力状态检查量表(Mini-mental State Examination,MMSE)评估认知功能,患者健康问卷抑郁量表(Patient health questionnaire-9,PHQ-9)评估抑郁程度,Epworth嗜睡量表(Epworth Sleepiness Scale,ESS)评估过度日间嗜睡程度。分析受试者运动功能与认知、情绪及睡眠的相关性。结果收缩压、心率、PHQ-9、MMSE、ESS得分是TUGT时间的影响因素。TUGT时间与PHQ-9及ESS得分呈正相关,与收缩压、心率、MMSE得分呈负相关,与MMSE子成分中定向力、即刻记忆力及语言能力呈负相关,差异均具有统计学意义(均P<0.05)。logistic回归分析显示:PHQ-9得分升高(运动轻度异常组OR=1.099,95%CI:1.045~1.155,P<0.001;运动明显异常组OR=1.150,95%CI:1.066~1.242,P<0.001)、MMSE得分降低(运动轻度异常组OR=0.939,95%CI:0.886~0.995,P<0.033;运动明显异常组OR=0.793,95%CI:0.729~0.862,P<0.001)、ESS得分升高(运动轻度异常组OR=1.139,95%CI:1.094~1.186,P<0.001;运动明显异常组OR=1.203,95%CI:1.132~1.279,P<0.001)与运动功能下降独立相关。结论抑郁状态、认知障碍及过度日间嗜睡与社区老年人群运动功能下降具有相关性,TUGT可用于社区老年人群的运动功能下降的早期筛查。
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