Background: Cancer biomarker plays an important role in detecting cancer as well as the mechanism of cancer occurrence and *** the development of transcriptomics research, especially the widely used high-throughput mi...
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Background: Cancer biomarker plays an important role in detecting cancer as well as the mechanism of cancer occurrence and *** the development of transcriptomics research, especially the widely used high-throughput microarray chip and RNA sequencing technology, researchers have obtained a large number of tumor related data and information on he transcriptional *** such a mass of data and information, how to identify clinical biomarkers systematically and efficiently has become one of advanced research projects of cancer biomarker research.
In many informational fields,such as biological,environmental,medical,etc.,lots of sets of data are created every day.A flexible system biology tool enables to analysis the biology metabolize network in question with ...
In many informational fields,such as biological,environmental,medical,etc.,lots of sets of data are created every day.A flexible system biology tool enables to analysis the biology metabolize network in question with efficiency and *** work gave a hybrid system based on the deep clustering algorithm,computing the co-regulated genes,also called regulons or co-regulation *** experiment results,based on the hypergeometric distribution function scores,showed that the model-based deep clustering (MBDC),was more efficient and accurate than other network functions as ISA,BIMAX,XMOTIFS,QUBIC and *** further study showed that MBDC was not only available in cancer analysis,but also in some bacteria study such as Eschedchia coli.
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