目的:通过文献计量学方法和可视化分析工具CiteSpace,探究近10年中医药干预脓毒血症的研究现状和发展趋势。方法:以中国知网(CNKI)数据库为数据源,检索2004年至2024年间关于中医药干预脓毒血症的研究文献,利用CiteSpace软件对文献的年发文量、作者、机构、关键词等进行分析。结果:共纳入文献198篇,发文量总体呈上升趋势;主要研究机构地域上集中于广州、黑龙江、江西等地,广州中医药大学发文量最高,机构之间形成了若干合作网络,主要为高等院校及其附属医院合作为主;关键词聚类结果显示研究热点集中在中医药治疗脓毒血症及相关疾病(如急性肾损伤、肺损伤)的机制研究,以及中西医结合、活血化瘀等治疗方法的应用。结论:中医药干预脓毒血症的研究取得了显著进展,但在研究深度和广度上仍有待提高,未来研究应加强对中医药作用机制的探索,交叉学科的结合将成为热点研究趋势。Objective Through bibliometric methods and visual analysis tool CiteSpace, this paper explores the research status and development trend of traditional Chinese medicine intervention in sepsis in the past 10 years. Methods CNKI database was used as the data source to search the research literature on the intervention of traditional Chinese medicine in sepsis from 2004 to 2024. CiteSpace software was used to analyze the annual number of articles, authors, institutions and keywords. Results A total of 198 articles were included, and the number of articles was on the rise. The main research institutions are geographically concentrated in Guangzhou, Heilongjiang, Jiangxi and other places. Guangzhou University of Traditional Chinese Medicine has the highest number of papers, and several cooperation networks have been formed between institutions, mainly for the cooperation of colleges and universities and their affiliated hospitals;the results of keyword clustering showed that the research hotspots focused on the mechanism of traditional Chinese medicine in the treatment of sepsis and related diseases (such as acute kidney injury and lung injury), as well as the application of integrated traditional Chinese and Western medicine, promoting blood circulation and removing blood stasis and other treatment methods. Conclusion The research on the intervention of sepsis by traditional Chinese medicine has made significant progress, but the depth and breadth of research still need to be improved. In the future research, the exploration of the mechanism of action of traditional Chinese medicine should be s
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