心肌炎是各种原因(病毒感染、免疫系统激活、暴露于毒素或药物等)引起的心肌局限性或弥漫性炎症病变,可导致心脏收缩、舒张功能受损。本文报道1例慢性病程,急性发作,以来势汹汹的呼吸困难、不明原因的心源性休克等为临床表现的慢性活动性心肌炎病例。该病例提示按心脏病常规治疗后临床症状未缓解甚至继续加重时,完善相关检查后排除急性冠脉综合征、缺血性心肌病等,需考虑诊断心肌炎。Myocarditis, characterized by localized or widespread inflammation of the heart muscle, can stem from a variety of triggers such as viral infections, immune system reactions, or exposure to toxins and medications. This condition may result in compromised heart function, affecting both its ability to contract (systolic function) and relax (diastolic function). The case study presented here describes a chronic active myocarditis with a protracted course that manifested acutely, presenting with severe shortness of breath and unexplained cardiogenic shock. It underscores the importance of considering myocarditis as a potential diagnosis when conventional heart disease treatments fail to alleviate symptoms or when they worsen. In such instances, after conducting the necessary diagnostic tests, it is crucial to rule out acute coronary syndrome and ischemic cardiomyopathy before entertaining the possibility of myocarditis.
目的通过对基于国家健康和营养检查调查(NHANES)数据库在肝脏疾病领域相关研究进行文献计量学统计及可视化分析,分析近20年该领域的热点和挖掘趋势。方法基于Web of Science核心数据库合集(WoSCC)以及CiteSpace分析软件,对1998年12月至2...
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目的通过对基于国家健康和营养检查调查(NHANES)数据库在肝脏疾病领域相关研究进行文献计量学统计及可视化分析,分析近20年该领域的热点和挖掘趋势。方法基于Web of Science核心数据库合集(WoSCC)以及CiteSpace分析软件,对1998年12月至2022年12月发表文献进行计量学可视化分析,分析内容为发表文章的年度分布、被引情况、关键词的共现、聚类、时间线图和国家、机构、基金等。结果通过对313篇基于NHANES数据库的肝脏疾病领域文献进行可视化分析显示,该领域的发文量呈逐年递增,美国是发文量及中心性居首,伊诺瓦卫生系统为发文量最多的机构,美国卫生部人类服务部是资助该领域最多的基金资助机构,对关键词共现、聚类、时间线图分析提示非酒精性脂肪性肝病、代谢相关脂肪性肝病(MAFLD)、肝纤维化、代谢综合征方面为研究热门。结论代谢性肝病、病毒性肝炎和肝纤维化是肝病的主要研究热点。流行病学调查、危险因素评估和诊断方法是主要的分析方法。营养干预和肝病预防是未来的研究方向。机器学习在数据挖掘中具有广泛的适用性。
多形性透明变性血管扩张瘤(PHAT)是由Smith等人在1996年提出的一种罕见的低级别间叶源性肿瘤。WHO在2020年将其归类于分化未定的低度恶性肿瘤。组织学上PHAT的显着特征是存在扩张血管簇、条索状分布于扩张性血管之间的梭形和圆形瘤细胞及血管壁、血管周围及瘤细胞之间基质明显透明样变性。现报告我院1例大腿多形性透明变性血管扩张瘤患者,并分析此例患者的相关资料,汇总临床、影像及病理特点。病例男,56岁。发现左大腿内侧皮下肿物4年,近1年来自觉肿块较前明显增大。Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare low grade mesenchymal origin tumour proposed by Smith et al. in 1996. WHO classified it as a low grade malignant tumour with undifferentiated differentiation in 2020. Histologically the distinguishing features of PHAT are the presence of clusters of dilated blood vessels, strips of spindle shaped and rounded tumour cells distributed between dilated blood vessels and marked hyaline-like degeneration of the vascular wall, perivascular area and stroma between tumour cells. We report a case of pleomorphic hyaline degenerative angiodysplasia of the thigh in our hospital, and analyse the relevant data of this patient, summarizing the clinical, imaging and pathological features. The case was a 56-year-old man. A subcutaneous mass was found in the left inner thigh for 4 years, and in the past 1 year, the mass had increased significantly compared with the previous one.
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