目的系统评价针刺治疗功能性肠病(FBD)的神经影像学研究,探讨针刺治疗FBD的中枢机制。方法系统检索中国知网、万方、Web of Science、Embase、PubMed 5个数据库,筛选纳入基于神经影像技术的针刺治疗FBD临床研究,分析总结研究设计,整理...
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目的系统评价针刺治疗功能性肠病(FBD)的神经影像学研究,探讨针刺治疗FBD的中枢机制。方法系统检索中国知网、万方、Web of Science、Embase、PubMed 5个数据库,筛选纳入基于神经影像技术的针刺治疗FBD临床研究,分析总结研究设计,整理针刺干预对FBD患者脑功能活动模式的影响。结果共筛选304篇,纳入9篇文献,这些研究从即时影响和长期效应两个方面探讨了针刺治疗FBD的中枢机制,发现单次针刺显著影响了FBD患者扣带回、丘脑等区域功能活动,疗程针刺治疗显著调节了FBD患者前扣带回、脑岛、海马等区域的功能活动及连接模式。结论针刺可能通过调节FBD患者前扣带回、脑岛、丘脑等区域的功能活动及连接模式实现治疗作用。
Background:Reinforcing-reducing manipulations are a crucial part of acupuncture *** reinforcing manipulation with heat sensation(RMHS) and the reducing manipulation by inducing cool sensation(RMCS) are two representat...
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Background:Reinforcing-reducing manipulations are a crucial part of acupuncture *** reinforcing manipulation with heat sensation(RMHS) and the reducing manipulation by inducing cool sensation(RMCS) are two representative methods of reinforcing-reducing *** trial aims to investigate the characteristic of cerebral responses to these two typical acupuncture ***:A total of 35 healthy participants will be included and receive acupuncture stimulation with RMHS and RMCS in a random *** psychology,cognition,and body constitution of participants will be measured by the Self-rating Anxiety Scale(SAS),the Self-rating Depression Scale(SDS),the mindful attention awareness scale(MAAS),the Constitution in Chinese Medicine Questionnaire(CCMQ),and the needle sensation will be evaluated after each acupuncture stimulation *** cerebral activity changes elicited by RMHS and RMCS will be detected by functional near-infrared spectroscopy(fNIRS)and analyzed with the general linear model-based activation and the channel-to-channel functional ***:This trial will investigate the cerebral response induced by RMHS and RMCS by real-time fNIRS,so as to map the characteristics of the central responses’ patterns to these two manipulations and preliminarily explore the mechanism of traditional acupuncture manipulations.
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