禽流感(Avian influenza,AI)和马立克氏病(Marek′s disease,MD)是严重危害全球养禽业发展的两个主要病毒性传染病。目前,疫苗免疫是防控这两种病毒性疾病有效手段之一。在众多病毒活载体疫苗中,火鸡疱疹病毒(Herpesvirus of turkey,HVT...
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禽流感(Avian influenza,AI)和马立克氏病(Marek′s disease,MD)是严重危害全球养禽业发展的两个主要病毒性传染病。目前,疫苗免疫是防控这两种病毒性疾病有效手段之一。在众多病毒活载体疫苗中,火鸡疱疹病毒(Herpesvirus of turkey,HVT)以其独特的优势备受青睐,而以HVT表达禽流感病毒保护性抗原是目前的研究热点之一。本文对以HVT作为疫苗载体的优势和构建载体疫苗的影响因素(外源基因、启动子、复制非必需区的选择等)进行多方面分析,并对目前AI-HVT重组疫苗的研究进展进行综述。
Pasteurella multocida,the causative agent of fowl cholera,is a serious threat to poutry *** this study,we isolated and identified 40 Pasteurella multocida strains in fowl cholera outbreaks in Jiangsu province,*** iden...
Pasteurella multocida,the causative agent of fowl cholera,is a serious threat to poutry *** this study,we isolated and identified 40 Pasteurella multocida strains in fowl cholera outbreaks in Jiangsu province,*** identified *** was further characterized using multi-locus sequence typing(MLST).All of the 40 *** strains studied are genetically identical and belong to the ST129 sequence type based on seven MLST *** study provides evidence of a circulating epidemic strain of *** in Jiangsu,China.
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