Although the activation of Ras pathway is frequently observed in human hepatocellular carcinoma(HCC),the in vivo role of Ras activation in HCC initiation and progression is *** test the consequence of Kras activation ...
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Although the activation of Ras pathway is frequently observed in human hepatocellular carcinoma(HCC),the in vivo role of Ras activation in HCC initiation and progression is *** test the consequence of Kras activation in hepatocyte,we generated a hepatocyte-specific Kras612D transgenic mouse strain and observed spontaneous development of HCC in these ***,HBV X protein(HBx)expression significantly promotes the formation and malignant
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