In many informational fields,such as biological,environmental,medical,etc.,lots of sets of data are created every day.A flexible system biology tool enables to analysis the biology metabolize network in question with ...
In many informational fields,such as biological,environmental,medical,etc.,lots of sets of data are created every day.A flexible system biology tool enables to analysis the biology metabolize network in question with efficiency and *** work gave a hybrid system based on the deep clustering algorithm,computing the co-regulated genes,also called regulons or co-regulation *** experiment results,based on the hypergeometric distribution function scores,showed that the model-based deep clustering (MBDC),was more efficient and accurate than other network functions as ISA,BIMAX,XMOTIFS,QUBIC and *** further study showed that MBDC was not only available in cancer analysis,but also in some bacteria study such as Eschedchia coli.
Introduction Reconstruction of biological pathways is often done through mapping well-characterized pathways of model organisms to a target genome,typically through orthologous gene mapping.A limitation of such pathwa...
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Introduction Reconstruction of biological pathways is often done through mapping well-characterized pathways of model organisms to a target genome,typically through orthologous gene mapping.A limitation of such pathway-mapping approaches is that the mapped pathway models are limited by the compositions of the template pathways,i.e.,some genes in a target pathway may not have corresponding genes in the template pathways,the so-called"missing gene"problem.
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