重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)治疗专家共识由中国医师协会神经调控专业委员会电休克与神经刺激学组专家团队编写。专家共识根据截至2017年11月发表的临床研究并基于循证医学标准,发布rTMS在临床...
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重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)治疗专家共识由中国医师协会神经调控专业委员会电休克与神经刺激学组专家团队编写。专家共识根据截至2017年11月发表的临床研究并基于循证医学标准,发布rTMS在临床中的治疗方案推荐,包括:抑郁症、疼痛、运动障碍、中风、癫痫、耳鸣、焦虑障碍、强迫症、精神分裂症、物质成瘾和睡眠障碍等疾病。专家共识介绍了临床上rTMS治疗的安全性和有效性,并规范了治疗流程和操作技术。旨在为从事rTMS治疗的临床工作人员制定培训和应用的专业标准,最大程度上提高治疗效果,促进该治疗技术未来的发展。
精神分裂症是临床常见的严重精神疾病之一,临床上很多患者对药物治疗疗效欠佳.重复经颅磁刺激(rePetitive transcranial magnetic stimulation,rTMS)技术以无创、无痛、安全被广泛应用精神、神经、康复领域,它通过时变磁场作用于大脑皮...
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精神分裂症是临床常见的严重精神疾病之一,临床上很多患者对药物治疗疗效欠佳.重复经颅磁刺激(rePetitive transcranial magnetic stimulation,rTMS)技术以无创、无痛、安全被广泛应用精神、神经、康复领域,它通过时变磁场作用于大脑皮层,产生感应电流影响脑内神经电生理活动.rTMS作为一项新型神经调控技术,在临床上已用于多种精神疾病的辅助治疗,并取得了一定成效.本文主要对重复经颅磁刺激技术在治疗精神分裂症中的相关参数、疗效和安全性进行阐述.
The present study aimed to explore the possible associations between the dorsolateral prefrontal cortex(DLPFC) metabolites and the cognitive function in first-episode schizophrenia(FES).This study included 58 patients...
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The present study aimed to explore the possible associations between the dorsolateral prefrontal cortex(DLPFC) metabolites and the cognitive function in first-episode schizophrenia(FES).This study included 58 patients with FES(29 males and 29 females;mean age,22.66 ± 7.64 years) recruited from the First Affiliated Hospital,College of Medicine,Zhejiang University,and 43 locally recruited healthy controls(16 males and 27 females;mean age,23.07 ± 7.49 years).The single-voxel proton magnetic resonance spectroscopy was used to measure the levels of N-acetylaspartate(NAA),complex of glutamate,glutamine,and y-aminobutyric acid(Glx),choline-containing compounds and myo-inositol in the *** ratios of metabolites to creatine(Cr) were *** cognitive function was assessed by Measurement and Treatment Research to Improve Cognition in Schizophrenia(MATRICS) Consensus Cognitive Battery(MCCB).Correlation analysis was used to assess the relationships between the DLPFC metabolites and the cognitive *** with the healthy controls,the patients with FES showed significantly reduced scores in each part of the MCCB,significantly reduced NAA/Cr,and significantly increased Glx/Cr in the left *** performance in verbal learning and visual learning was correlated to the reduced NAA/Cr ratio in the left *** findings suggest that a lower NAA/Cr ratio in the left DLPFC is associated with the cognitive deficits in patients with FES,and may be an early biochemical marker for the cognitive impairment in schizophrenia.
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