中医香疗体系作为中医药体系的重要组成部分之一,在防治疾病,养生保健方面发挥着独特作用,而香薰作为中医香疗开展的重要手段之一,以其绿色天然,简便易携等优势,在当代为各阶段人群较广泛的接受。本文将在基于肯·威尔伯的整合心理学的视角下,对现代中医香疗在心理调节上的相关文献资料进行梳理总结,探讨中医香疗在当代对于情绪心理的调节作用及其机制,探索整合视域下中医香疗的“香–情–境”三维情境增强体系搭建,以期能为现代心理亚健康问题的解决提供新的思路,找到中医香疗继承发展的新方向,进一步推动中医香疗在现代生活与医疗中的应用。As one of the important parts of Chinese medicine system, Chinese medicine aromatherapy system plays a unique role in disease prevention and health care, and aromatherapy, as one of the important means of Chinese medicine aromatherapy, is widely accepted by people of all stages of life in contemporary times due to its advantages of green and natural, simple and easy to carry, and so on. In this paper, based on Ken Wilber’s perspective of integrative psychology, we will summarise the relevant literature on the psychological regulation of modern TCM aromatherapy, discuss the role of TCM aromatherapy in the regulation of emotional psychology and its mechanism in contemporary times, and explore the three-dimensional mood enhancement system of aroma-emotion-situation of TCM aromatherapy under the perspective of integration. The three-dimensional context enhancement system of Chinese medicine aromatherapy under the integrated perspective is constructed in order to provide new ideas for the solution of modern mental sub-health problems, to find a new direction for the inheritance and development of Chinese medicine aromatherapy, and to further promote the application of Chinese medicine aromatherapy in modern life and medical treatment.
目的:挖掘中医外用药治疗糖尿病足溃疡的用药规律,分析相关的药物靶点及疾病通路,探索核心组方的潜在作用机制。方法:对中国知网、万方、维普、中国生物医学文献、Pubmed等数据库中有关中药外用治疗糖尿病足溃疡的临床文献进行检索,通过IBM SPSS Modeler 18.0及IBM SPSS Statistics 26.0软件进行关联规则及聚类分析。利用TCMSP、SymMap、DisGenet、Genecards、TTD、OMIM、DrugBank等数据库及Cytoscape、DAVID软件进行网络药理学分析。结果:共筛选出164篇文献,148首外用处方,高频药物前6位依次为黄柏、当归、冰片、血竭、白芷和紫草。中药药性以寒、温为主,药味以辛、苦、甘味为主,归经以肝、脾经为主。178味中药关联分析得到4组关联药物,高频药物聚类分析得到2类组合。核心药物组合治疗糖尿病足溃疡的主要成分为槲皮素、棕榈酸、山达海松酸等,核心靶点为ESR1、EGFR、IL6等;主要信号通路包括PI3K-Akt、AGE-RAGE、MAPK等。结论:活血化瘀、清热补虚是中医外用方药治疗糖尿病足溃疡的基本法则,用药多为活血化瘀类药物与清热药、补虚药配伍使用,同时通过使用冰片等天然经皮吸收促透剂、提高外用药物使用剂量来增加皮肤对药物的吸收;数据挖掘得到的药对组合可为糖尿病足溃疡的临床选方用药提供参考;现代生物学机制可能与减轻炎症反应、促进血管新生等相关。Objective: To explore the medication rule of external medicine in treating diabetes foot ulcers, analyze related drug targets and disease pathways, and explore the potential mechanism of core prescriptions. Methods: The clinical literature on the treatment of diabetes foot ulcers with external use of traditional Chinese medicine in the databases of CNKI, Wanfang, VIP, Chinese biomedical literature, Pubmed, etc. were searched, and the association rules and cluster analysis were carried out through IBM SPSS Modeler 18.0 and IBM SPSS Statistics 26.0 software. Perform network pharmacology analysis using databases such as TCMSP, SymMap, DisGenet, Genecards, TTD, OMIM, DrugBank, as well as Cytoscape and DAVID software. Result: A total of 164 articles and 148 topical prescriptions were screened, and the top 6 high-frequency drugs were Huangbai, Danggui, Borneol, Xuejie, Baizhi, and Zicao. The medicinal properties of traditional Chinese medicine are mainly cold and warm, and the medicinal flavors are mainly spicy, bitter, and sweet. The meridian tropism is mainly based on the liver and spleen meridians. Association analysis of 178 traditional Chinese medicines resulted in 4 groups of associated drugs, and high-frequency drug clustering analysis resulted in 2 combinations. The main components of the core drug combination for the treatment of diabetes foot ulcers are qu
目的:利用文献计量学方法对近10年铜死亡相关的国内外文献进行可视化分析,以便更好地了解铜死亡的研究进展,寻找潜在的研究方向。方法:以中国知网、万方、Web of Science核心数据库为数据来源,使用CiteSpace软件对2014年1月1日~2024年9...
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目的:利用文献计量学方法对近10年铜死亡相关的国内外文献进行可视化分析,以便更好地了解铜死亡的研究进展,寻找潜在的研究方向。方法:以中国知网、万方、Web of Science核心数据库为数据来源,使用CiteSpace软件对2014年1月1日~2024年9月30日有关铜死亡研究的相关文献进行发文量、国家、作者、机构和关键词的可视化分析。结果:铜死亡发文量近几年迅速增加,中国在发文数量上居首位,但中心性低于二、三名,即美国和印度;国内发文量前4的作者是王议贤、曹建平、焦旸、朱巍;机构间合作较少;热点话题主要集中在细胞凋亡、自噬、氧化应激等机制和相关疾病的探索上;神经退行性疾病和癌症是与铜死亡密切相关的疾病。结论:早期铜死亡发病机制的研究是铜死亡机制研究领域的热点,后期逐渐呈现出发病机制与临床疾病并行研究的趋势。
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