Methods: Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative in rescuing highly endangered species and can be used as a model for studying nuclear-cytoplasmic ***, iSCNT emb...
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Methods: Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative in rescuing highly endangered species and can be used as a model for studying nuclear-cytoplasmic ***, iSCNT embryos often fail to produce viable *** alterations of normal molecular mechanisms contributing to extremely poor development is for the most part unknown.
Background: It is well known that histone modifications can control gene expression, and the data of histone modifications have grown exponentially by the next-generation sequencing *** on these data, many theoretical...
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Background: It is well known that histone modifications can control gene expression, and the data of histone modifications have grown exponentially by the next-generation sequencing *** on these data, many theoretical works for epigenetics researches could be *** dealing with such big data is quite difficult and time-consuming, which really is a challenge for computational *** epigenetic modification is cell-type specific, so we chose one important cell type, the human embryonic stem (ES) cell, to study the relationship between histone modifications and gene expression levels.
Background: The abnormally methylated DNA can lead to carcinogenesis and some *** methylation, which mostly occurs at CpG sites, is one of epigenetic changes and plays a key role in regulatory gene expression.
Background: The abnormally methylated DNA can lead to carcinogenesis and some *** methylation, which mostly occurs at CpG sites, is one of epigenetic changes and plays a key role in regulatory gene expression.
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